Visible-light-induced photocatalyst-free cascade cyclization of 3-(2-(ethynyl)phenyl)quinazolinones to sulfonated quinolino[2,1-b]quinazolinones

Abstract

A visible-light-induced K2S2O8-promoted cascade sulfonation/cyclization reaction to afford a series of sulfonated quinolino[2,1-b]quinazolinones has been developed under mild conditions.

Visible-light promoted radical cascade cyclization of 3-allyl-2-arylquinazolinones for the synthesis of phosphorylated dihydroisoquinolino[1,2-b]quinazolinones

“…12 Subsequently, such aryl alkynes were used as substrates to produce thiocyanate/trifluoromethylthio/sulfonyl-containing quinolino[2,1- b ]quinazolinones by other groups. 13 Very recently, the photocatalytic metal-free cyclization reactions of 3-(2-isocyanophenyl)quinazolin-4(3 H )-ones, a new kind of building unit, were developed to afford novel ether substituted tetracyclic quinoxalino[2,1- b ]quinazolinones by the group of Pan and Yu (Scheme 1d). 14…”