Vision-Related Functional Burden of Diabetic Retinopathy Across Severity Levels in the United States

Willis, Jeffrey R.; Doan, Quan V.; Gleeson, Michelle; Hašková, Zdenka; Ramulu, Pradeep Y.; Morse, Lawrence S.; Cantrell, Ronald A.

doi:10.1001/jamaophthalmol.2017.2553

Cited by 114 publications

(68 citation statements)

References 27 publications

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“… 34 The history of comorbid age-related ocular diseases, including cataract, glaucoma, and retinopathy, was based on the questionnaire and/or retinal images in accordance with previous studies. 35 , 36 , 37 Walking disability was defined by self-report of difficult walking or need of special equipment for walking. Self-rated health status was dichotomized as poor to fair or good to excellent.…”

Section: Methodsmentioning

confidence: 99%

Association of Age-Related Macular Degeneration With Risk of All-Cause and Specific-Cause Mortality in the National Health and Nutrition Examination Survey, 2005 to 2008

et al. 2019

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Key Points Question What is the association of age-related macular degeneration with mortality outcomes among older adults? Findings In this cohort study of 5603 participants 40 years or older, only late age-related macular degeneration was associated with more than a doubling of all-cause mortality and more than 3-fold higher risk of mortality not due to cardiovascular disease and cancer. Meaning The association of late age-related macular degeneration and poor survival may shed light on mechanisms underlying the disease, indicating that late age-related macular degeneration may be a marker of frailty and aging or may be due to residual confounding factors indicative of aging.

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Section: Methodsmentioning

confidence: 99%

Association of Age-Related Macular Degeneration With Risk of All-Cause and Specific-Cause Mortality in the National Health and Nutrition Examination Survey, 2005 to 2008

et al. 2019

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“…(13) A recent study on about one thousand subjects with diabetes showed that 25.4% of the patients had mild and moderate non-proliferative diabetic retinopathy, and 2.3% had severe non-proliferative diabetic retinopathy or proliferative diabetic retinopathy. (14) Another investigation in the United States indicated that out of 2240 youths with type 1 diabetes mellitus and 1768 youths with type 2 diabetes mellitus, 20.1% and 7.2% developed diabetic retinopathy over a median follow-up time of 3.2 and 3.1 years, respectively, showing that youths with types 1 or 2 diabetes mellitus are at a considerable risk for diabetic retinopathy and should undergo regular screenings. (15)…”

Section: United Statesmentioning

confidence: 99%

Epidemiological Aspects of Diabetic Retinopathy- A Narrative Review

Rasoulinejad¹

2019

jemds

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“…Diabetic retinopathy is one of the main microvascular complications of diabetes mellitus and can threaten the sight and progress to blindness [17,18] . National and international studies that have been conducted to determine the prevalence of diabetic retinopathy have reported values that range from 15% in some studies to 36% in others [19][20][21][22][23].…”

Section: Discussionmentioning

confidence: 99%

The Impact of Expanding the Screening Interval for Diabetic Retinopathy in Primary Care Centers

Bardisi¹,

Magliah²,

Alatta³

2018

Health Prim Car

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Objectives: This study aimed to estimate the prevalence of diabetic retinopathy (DR) and its determinant risk factors in people with diabetes attending primary care centers and to determine the impact of expanding the screening interval on the incidence and progression of (DR). Methodology:This study was a cross-sectional chart review, that was conducted in three randomly selected primary care centers. A total of 250 diabetic patients had three consecutive annual screenings for DR from April 2014 to April 2017. At the initial visit, the ophthalmological findings were recorded. For three successive yearly screening , the screening results were assessed to estimate the changes that occurred in the prevalence, incidence, and progression of diabetic retinopathy in addition to the degree of association with the most predictable risk factors.Results:The initial prevalence of DR was 15.2%. Over the three-consecutive annual screening, the DR prevalence increased to 19.6%, 22.4%, and 25.6%, respectively. Most cases (72%) of DR were of the mild non-proliferative diabetic retinopathy (NPDR) type. The annual incidence of DR was 4.4%, 2.8%, and 3.2%. The progression of DR occurred in 2 (0.08%) cases at the second screening interval and in 6 (2.4%) cases at the third screening interval. These changes were strongly associated with age, the duration of diabetes, HBA1C levels, hypertension, and insulin therapy (P-value 0.005). However, changes in the incidence and progression of DR over the three intervals were statistically non-significant (P-value 0.086).Conclusion: DR, a serious microvascular complication of diabetes mellitus, is an asymptomatic disease with a slow onset and gradual progression. DR requires regular screening for early detection. The screening interval can be extended up to every three years in the very low-risk groups without threatening vision.

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Vision-Related Functional Burden of Diabetic Retinopathy Across Severity Levels in the United States

Abstract: IMPORTANCE Among adults with diabetes in the United States, severe forms of diabetic retinopathy (DR) are significantly associated with a greater vision-related functional burden.OBJECTIVE To assess the functional burden of DR across severity levels in the United States.

Cited by 114 publications

References 27 publications

Association of Age-Related Macular Degeneration With Risk of All-Cause and Specific-Cause Mortality in the National Health and Nutrition Examination Survey, 2005 to 2008

Association of Age-Related Macular Degeneration With Risk of All-Cause and Specific-Cause Mortality in the National Health and Nutrition Examination Survey, 2005 to 2008

Epidemiological Aspects of Diabetic Retinopathy- A Narrative Review

The Impact of Expanding the Screening Interval for Diabetic Retinopathy in Primary Care Centers

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