Visits to the Emergency Room for Asthma Attacks and Short-Term Variations in Air Pollution

Boutin-Forzano, S.; Adel, N.; Gratecos, L; Jullian, H.; Garnier, J.-M.; Ramadour, M.; Lanteaume, A.; Hamon, Martin; Lafay, V.; Charpin, D.

doi:10.1159/000076673

Cited by 43 publications

(21 citation statements)

References 5 publications

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“…Although several studies have related pollen exposure to AR [18,19], few have employed objective assessments of exposure to pollen [18,19]. In addition, although epidemiologic studies have largely explored the respiratory effects of air pollution, these have primarily focused on the lower airways [20,21,22]. Associations between the prevalence of AR and NO 2 have been highlighted by few population studies [23,24].…”

Section: Discussionmentioning

confidence: 99%

Grass Pollen Counts, Air Pollution Levels and Allergic Rhinitis Severity

Annesi‐Maesano

Rouve

Desqueyroux

et al. 2012

Int Arch Allergy Immunol

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Background: Little is known about the relation between allergic rhinitis severity and airborne pollen in combination with air pollutants. Objective: To model the risk of suffering from severe seasonal allergic rhinitis (SAR) as a function of both pollen count and air pollution levels in a large nationwide sample of patients whose SAR was diagnosed by a physician and confirmed by skin prick test positivity or specific immunolglobulin E to common aeroallergens. Methods: The severity of SAR symptoms was estimated with the Symptomatic Global Score (SGS) among 36,397 patients suffering from an untreated and uncomplicated SAR between May and August 2004 in metropolitan France. Patients who had an SGS in the upper third quartile were classified as suffering from severe SAR. A multilevel model relating SAR severity, pollen and air pollution was used to take into account the hierarchical data structure. Results: 18.9% of the 17,567 urban patients retained for the analysis suffered from severe rhinitis. At the Lag0 (day of the visit), a rise of 60 grass pollen grains/m³ increased the risk of suffering from a severe SAR form by 8% in the multileveled model after adjusting for potential confounders and air pollution levels. Results were also confirmed in the subsample of individuals with documented sensitization to grass pollen. Conclusion: Grass pollen count aggravated SAR in terms of symptoms in our nationwide sample. These findings confirm the need for proper treatment and preventive measures in SAR patients sensitized to grass pollen.

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Section: Discussionmentioning

confidence: 99%

Grass Pollen Counts, Air Pollution Levels and Allergic Rhinitis Severity

Annesi‐Maesano

Rouve

Desqueyroux

et al. 2012

Int Arch Allergy Immunol

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“…However, as many aspects of weather affect air quality, the role of each aspect separately is not that clear [30, 31]. On the other hand, increased levels of pollutants, especially PM 10 , NO 2 , SO 2 and O 3 , have been repeatedly found to be associated with asthma attacks, and some air pollution-related episodes of asthma exacerbation are due to meteorological factors that favour the accumulation of air pollutants at ground level [15, 16,30,31,32,33]. …”

Section: Discussionmentioning

confidence: 99%

Association of Weather Conditions with Childhood Admissions for Wheezy Bronchitis or Asthma in Athens

Priftis

Παλιατσός²,

Panagiotopoulou-Gartagani³

et al. 2006

Respiration

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Background: The association between asthma morbidity and meteorological conditions is well documented, but it is not clear to what extent more specific meteorological variables are implicated. Objectives: This study was aiming to investigate whether there is any association between specific meteorological conditions and the seasonal variation and the rate of asthma admissions among children in Athens. Methods: Data were obtained retrospectively from hospital registries of the three main Children’s Hospitals in Athens during a 23-year period (1978–2000). The meteorological database consisted of mean monthly values of eight meteorological variables. The whole period studied was divided into three time periods: 1978–1987, 1988–1993 and 1994–2000. Results: A clear seasonal trend with a permanent pattern was detected. There were more monthly asthma admissions in winter-spring and autumn for younger children, as well as a lower peak in winter and autumn and a major one in May for older children, without significant differences in between the three time periods. The results of a multiple regression analysis revealed that relative humidity and atmospheric pressure were predictors of up to 56.7% (1988–1993) and 59.2% (1994–2000) monthly asthma admissions among younger children. No relation of the time trend in asthma admissions during the periods studied for any age group with any of the meteorological variables was detected. Conclusions: Our results indicate a constant seasonal variability in asthma admissions among children in Athens, whereas relative humidity and atmospheric pressure are the more implicated meteorological variables for younger asthmatic children.

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“…55 Indeed, air pollutants, particularly ozone, can induce or worsen asthma. 56,57 Thus, a high expression of C5aR in the epithelium could play a role in the inflammatory response elicited by environmental stimuli such as infectious agents, allergens, and pollutants.…”

Section: Discussionmentioning

confidence: 99%