Visual Acuity and Fixation Characteristics in Age-Related Macular Degeneration

Cacho, Isabel; Dickinson, Christine; Reeves, Barnaby C; Harper, Robert A.

doi:10.1097/opx.0b013e318073c2f2

Cited by 18 publications

(15 citation statements)

References 18 publications

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“…For reading, a PRL left or right of the scotoma would mean that text letters on the attended line would disappear into the scotoma, so placement of the PRL above or below the scotoma would be advantageous. But 34-60% of patients adopt a PRL left of their scotoma (Guez et al 1993, Fletcher & Schuchard 1997, Cacho et al 2007. Some others have reported that the majority of patients with macular disease, especially those with Stargardt disease, had a PRL below their scotoma (White & Bedell 1990, Reinhard et al 2007, Greenstein et al 2008.…”

Section: Oculomotor and Perceptual Plasticitymentioning

confidence: 99%

Low Vision and Plasticity: Implications for Rehabilitation

Legge

Chung

2016

Annu. Rev. Vis. Sci.

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Low vision is any type of visual impairment that affects activities of daily living. In the context of low vision, we define plasticity as changes in brain or perceptual behavior that follow the onset of visual impairment and that are not directly due to the underlying pathology. An important goal of low-vision research is to determine how plasticity affects visual performance of everyday activities. In this review, we consider the levels of the visual system at which plasticity occurs, the impact of age and visual experience on plasticity, and whether plastic changes are spontaneous or require explicit training. We also discuss how plasticity may affect low-vision rehabilitation. Developments in retinal imaging, noninvasive brain imaging, and eye tracking have supplemented traditional clinical and psychophysical methods for assessing how the visual system adapts to visual impairment. Findings from contemporary research are providing tools to guide people with low vision in adopting appropriate rehabilitation strategies.

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Section: Oculomotor and Perceptual Plasticitymentioning

confidence: 99%

Low Vision and Plasticity: Implications for Rehabilitation

Legge

Chung

2016

Annu. Rev. Vis. Sci.

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“…Both groups showed the expected increase of crowding with increased eccentricity. Recently, Cacho and co‐worker 59 found that subjects with ARMD exhibited only a small crowding effect, which was not greater than that documented in subjects with normal vision. We can conclude that early ARM does not increase contour interaction and that the increased crowding that has been documented in ARMD 11,60 may be because an eccentric retinal location is used for fixation, at which there is more crowding than at the fovea 43,61,62 .…”

Section: Discussionmentioning

confidence: 84%

Functional deficits in early stage age‐related maculopathy

Qiu

Leat

2009

Clinical and Experimental Optometry

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Background: It is of interest to examine paracentral functional deficits in early agerelated maculopathy (ARM), as histopathological studies indicate that this is where the earliest changes occur. The purpose of this study is to detect the sensory functional deficits at chosen retinal areas around the fovea and at the fovea itself in patients with early age-related maculopathy and to determine the type of functional losses that are more pronounced in early ARM. Methods: Ten participants with early ARM and 10 age-matched controls took part. Crowded and uncrowded visual acuity and static and transient contrast sensitivity were measured in the same selected eye of each participant at eight predetermined retinal locations plus the fovea in patients with early ARM and controls. All measurements were made using computer-generated targets. Results: A significant difference between the controls and subjects with ARM was found in low spatial frequency static contrast sensitivity (p = 0.05) but not for transient contrast sensitivity (p = 0.586). Visual acuity (uncrowded VA and crowded VA) showed a borderline difference (p = 0.072 and p = 0.084, respectively). Compared to controls, there was no evidence of increased contour interaction effects in early ARM (p = 0.595). Conclusion:The subjects with very early ARM showed significant loss of low spatial frequency static contrast sensitivity before the loss of high contrast VA, indicating that static contrast sensitivity may be one of the earliest functional losses in early ARM and this loss was found to extend across the central 10 degrees of the retina.

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“…These normality values should be checked in the patients with doubt central vision diagnosis as age-related macular degeneration [58], multiple sclerosis neuropathy [59], diabetic retinopathy [37], intoxications [20] and for a more controlled study of the early foveal involvement in glaucoma patients [51].…”

Section: Discussionmentioning

confidence: 99%

Aging Effects in Psychophysical Foveal Light Detection Thresholds

Pulchinelli¹

2013

PBS

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Foveal light detection sensitivity was evaluated in 348 volunteers covering a large age range using an automated perimetry performed in the Humphrey Field Analyzer II. Foveal sensitivity was measured using the Humphrey's 4-2 bracketing strategy with a 30 dB initial stimulus intensity, at an inferior visual field location, a 0.431 (4mm 2 , viewed at 30 cm; Goldmann III) spot of white light is presented on a 10 cd/m2 white background. The sensitivity measurement was performed monocularly in both eyes randomly chosen. Our results showed a negative moderate correlation between age and the light sensitivity detection of OD (r= -0.5591; p< 0.001) and OS (r= -0.6021, p< 0.001). A moderate positive correlation was obtained between the light sensitivity of the two eyes (r= -0.5986; p< 0.001). We conclude reporting aging effect in the foveal sensitivity light detection suggesting functional decrease in perceptual function guide by developmental changes. Tolerance limits for normative purposes were measured.

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Visual Acuity and Fixation Characteristics in Age-Related Macular Degeneration

Abstract: Although the acuity measured under different stimulus conditions varies, the absolute differences are small. This suggests that these techniques would not be helpful in determining fixation characteristics, or predicting the outcome of rehabilitation in individual patients with AMD.

Cited by 18 publications

References 18 publications

Low Vision and Plasticity: Implications for Rehabilitation

Low Vision and Plasticity: Implications for Rehabilitation

Functional deficits in early stage age‐related maculopathy

Aging Effects in Psychophysical Foveal Light Detection Thresholds

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