Visual Deprivation Myopia with Translucent and Black Goggles

Abstract

To study how different visual deprivation conditions influence the degree of myopia, chicks were reared under conditions of unilateral and bilateral visual deprivation with translucent and black goggles in environments of a 12-hour light/dark cycle and complete darkness. Two weeks after hatching, the refractive errors and axial lengths of the eyes were measured. The deprived eyes of the light/dark-reared chicks exhibited severe myopia both unilaterally and bilaterally as well as axial elongations. The dark-reared chicks exhibited slight myopia in the eyes with goggles and no significant axial elongation. The experiments suggest that different degrees of visual deprivation can also cause severe myopia, that myopia develops independently in each eye, and that a light/dark environment is required for severe myopia to develop.

Investigation of the association between all-trans-retinol dehydrogenase (RDH8) polymorphisms and high myopia in Chinese

“…Image defocus or blur on the retina can signal the eye to develop myopia in animals, whereas animals raised in a dark environment do not develop significant myopia (Hung et al, 1995;Norton and Siegwart, 1995;Yoshino et al, 1997). Therefore, myopia might be triggered at the level of photoreceptors or visual metabolism.…”

Heritability of Lenticular Myopia in English Springer Spaniels

“…While numerous experimental models of animal myopia have been reported (tree shrew, 2-8 chick, [9][10][11][12][13][14][15][16][17][18][19] guinea pig, [20][21][22][23][24] marmoset, [25][26][27][28][29][30] and primates 31 ), there is a dearth of reports of naturally-occurring myopia in animals. Recent reports of naturally-occurring myopia have been identified in dogs, 32,33 guinea pigs, 34 and a purpose-bred line of chickens with reduced vision.…”