Visual field mean deviation and relevant factors in 928 Chinese retinitis pigmentosa patients

Ye, Hui; Xia, Xiaoping

doi:10.18240/ijo.2018.12.17

Cited by 3 publications

(1 citation statement)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The severity of RP is assessed depending on the outcome of the patient’s visual field examination. visual field MS 27 and visual field MD 28 are relatively valuable indicators to evaluate the pathological status of patients in RP study. Therefore, visual field MS and visual field MD were measured as the main results in this study.…”

Section: Discussionmentioning

confidence: 99%

Acupuncture for retinitis pigmentosa: study protocol for a randomised, sham-controlled trial

Huang

Wang

et al. 2021

BMJ Open

View full text Add to dashboard Cite

IntroductionPrimary retinitis pigmentosa (RP) is a common hereditary retinal disease in ophthalmology that has a considerable impact on quality of life, but there are few effective therapeutic strategies. This trial aims to determine the efficacy and safety of acupuncture versus sham acupuncture (SA) for RP.Methods and analysisThis is a study protocol for a randomised, participant-blind, sham-controlled trial. 64 eligible patients with RP will randomly be divided into acupuncture group and SA group. All groups will receive 48 sessions over 3 months. Participants will complete the trial by visiting the research centre in month 6/9 for a follow-up assessment. The primary outcome is visual field mean sensitivity and visual field mean deviation at month 3/6/9 compared with baseline. Secondary outcomes include the best-corrected visual acuity, central macular thickness, subfoveal choroidal thicknes, traditional Chinese medicine syndrome score and the scale of life quality for diseases with visual impairment at month 3/6/9 compared with baseline. Adverse events and safety indexes will be recorded throughout the study. SPSS V.25.0 statistical software was used for analysis, and measurement data were expressed as mean±SD.Ethics and disseminationEthics approval was obtained from the Ethics Committee of the Chinese Clinical Trial Registry (approval no: ChiECRCT20200460). The results of this study will be published in a peer-reviewed journal, and trial participants will be informed via email and/or phone calls.Trial registration numberChiCTR2000041090.

show abstract

Section: Discussionmentioning

confidence: 99%

Acupuncture for retinitis pigmentosa: study protocol for a randomised, sham-controlled trial

Huang

Wang

et al. 2021

BMJ Open

View full text Add to dashboard Cite

show abstract

Genetic, environmental and other risk factors for progression of retinitis pigmentosa

Huang

Liang

et al. 2022

Int J Ophthalmol

View full text Add to dashboard Cite

Retinitis pigmentosa (RP) is a commonly inherited disease of the retina, which is characterized by progressive loss of visual function due to specific genetic mutations. There are many risk factors that may have effect on the progression of RP, such as inheritance patterns, genotype, gender, age, smoking, physical activity, and other demographic and environmental factors. Baseline visual field conditions, changes of ellipsoid zone, photoreceptor layer thickness, and choroidal structure are reported to be the phenotype risk factors for RP progression. Moreover, aqueous flare and high-sensitivity C-reactive protein are probable inflammation biomarkers for assessing the progression of RP. Increased oxidative stress is considered to be one of the potential factors for the existence of RP. The risk factors can be combined to form a corresponding prediction model to predict disease progression. This review is to summarize the current literature that studies the genetic, environmental, phenotypic, demographic, inflammatory and other risk factors of RP progression and discuss the most reliable risk factors that could provide predictive models.

show abstract

Does Stem Cell Implantation Have an Effect on Severity of Retinitis Pigmentosa: Evaluation with a Classification System?

Öner¹,

Kahraman²

2021

OJOph

View full text Add to dashboard Cite

Visual field mean deviation and relevant factors in 928 Chinese retinitis pigmentosa patients

Cited by 3 publications

References 19 publications

Acupuncture for retinitis pigmentosa: study protocol for a randomised, sham-controlled trial

Acupuncture for retinitis pigmentosa: study protocol for a randomised, sham-controlled trial

Genetic, environmental and other risk factors for progression of retinitis pigmentosa

Does Stem Cell Implantation Have an Effect on Severity of Retinitis Pigmentosa: Evaluation with a Classification System?

Contact Info

Product

Resources

About