Visual hallucinations of autobiographic memory and asomatognosia: a case of epilepsy due to brain cysticercosis

Orjuela-Rojas, Juan Manuel; Ramı́rez-Bermúdez, Jesús; Martínez‐Juárez, Iris E.; Kerik, Nora; Meneses, Iván Diaz; Pérez-Gay, Fernanda Juárez

doi:10.1080/13554794.2014.962548

Cited by 10 publications

(1 citation statement)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…32,33 While this is theoretically possible – and must indeed occur in a reduced percentage of cases – several pieces of evidence favor a causal relationship between NCC and recurrent nonprovoked seizures. Published evidence include abundant descriptions of cases with focal epilepsies related to the location of a single parasite in the brain parenchyma, 34–38 the higher prevalence of epilepsy in cysticercosis-endemic areas when compared with non-endemic regions, 39 and the occurrence of inflammatory changes surrounding parenchymal brain cysticerci immediately after a seizure in up to 50% cases. 40 In addition, while it has been suggested that some degenerating cysticerci may induce reactive seizures due to transient episodes of inflammation, calcified cysticerci – as those found in the present series – represent enduring epileptogenic lesions due to the gliosis that develops around dead parasites, as well as late exposure of residual antigenic material to the brain parenchyma.…”

Section: Discussionmentioning

confidence: 99%

On the relationship between calcified neurocysticercosis and epilepsy in an endemic village: A large‐scale, computed tomography–based population study in rural Ecuador

Brutto

Arroyo²,

Brutto

et al. 2017

Epilepsia

View full text Add to dashboard Cite

SUMMARY Objective Using a large-scale population-based study, we aimed to assess prevalence and patterns of presentation of neurocysticercosis (NCC) and its relationship with epilepsy in community-dwellers aged ≥20 years living in Atahualpa (rural Ecuador). Methods In a three-phase epidemiological study, individuals with suspected seizures were identified during a door-to-door survey and an interview (Phase I). Then, neurologists evaluated suspected cases and randomly selected negative persons to estimate epilepsy prevalence (Phase II). In Phase III, all participants were offered non-contrast CT for identifying NCC cases. The independent association between NCC (exposure) and epilepsy (outcome) was assessed by the use of multivariate logistic regression models adjusted for age, sex, level of education and alcohol intake. CT findings were subsequently compared to archived brain MRIs in a sizable subgroup of participants. Results Of 1,604 villagers aged ≥20 years, 1,462 (91%) were enrolled. Forty-one persons with epilepsy (PWE) were identified, for a crude prevalence of epilepsy of 28 per 1,000 population (95% C.I.: 20.7 – 38.2). A head CT was performed in 1,228 (84%) out of 1,462 participants, including 39 of 41 PWE. CT showed lesions consistent with calcified parenchymal brain cysticerci in 118 (9.6%) cases (95% C.I.: 8.1% – 11.4%). No patient had other forms of NCC. Nine of 39 PWE, as opposed to 109 of 1,189 participants without epilepsy, had NCC (23.1% versus 9.2%, p=0.004). This difference persisted in the adjusted logistic regression model (OR: 3.04; 95% C.I.: 1.35 – 6.81; p=0.007). Significance This large CT-based study demonstrates that PWE had three times the odds of having NCC than those without epilepsy, providing robust epidemiological evidence favoring the relationship between NCC and epilepsy.

show abstract

Section: Discussionmentioning

confidence: 99%

On the relationship between calcified neurocysticercosis and epilepsy in an endemic village: A large‐scale, computed tomography–based population study in rural Ecuador

Brutto

Arroyo²,

Brutto

et al. 2017

Epilepsia

View full text Add to dashboard Cite

show abstract

Localizing value of disturbances of self‐integration, depersonalization, and forced thinking: A systematic review

Etholm,

Ivanovic,

Larsen

et al. 2024

Epileptic Disorders

View full text Add to dashboard Cite

We performed a systematic review of the localizational value of disturbances of self‐integration, depersonalization and forced thinking in focal epilepsy with the aim to summarize the state‐of‐the‐art anatomo‐clinical correlations in the field and help guide interpretation of ictal semiology within the framework of pre‐surgical evaluation. The review was performed using a PRISMA‐ and QUADAS2‐based approach. Three separate PubMed and EMBASE searches were undertaken using the keywords self‐integration, depersonalization and forced thinking, along with synonyms, in combination with terms to identify epileptogenic zone as defined by surgical outcome, MRI‐findings or intracranially recorded EEG. Studies published in peer‐reviewed journals with an abstract available, limited to English, French, German, Spanish, or Italian were included for review. Abstracts from scientific meetings were included if precise data on semiology in addition to either localization or surgical outcome was presented. Cases were regarded as eligible if data informing on anatomo‐clinical correlations were sufficient to allow determination of an epileptogenic zone and evaluate its level of confidence. For disturbances of self‐integration, the search identified 18 publications containing 23 eligible cases, with 10 additional cases identified in the literature. For depersonalization, a single case from a two patient study fulfilled inclusion criteria. For forced thinking, the search identified two publications containing four eligible cases, with six additional cases identified through literature searches. The retrieved cases suggest that disturbances of self‐integration often reflect an epileptogenic zone centered around the temporoparietal region, where neighboring areas in the parietal lobe, the posterior insula, and likely depending on the type of disturbance also the adjoining occipital lobe, the anterior and middle cingulum, premotor and supplementary motor in addition to medial temporal structures could be involved. When present, lateralized symptomatology reflects a contralateral focus. Depersonalization, as a localizing ictal phenomenon was quite elusive. Forced thinking either pointed to premotor frontal or temporal epileptogenic zones. Currently, outlined epileptogenic zones of ictal disturbances of self‐integration and forced thinking are quite widespread and should be regarded with a low‐to‐moderate degree of reliability. A focus on such rarer ictal phenomena, in combination with improved imaging techniques and increased use of SEEG, will hopefully lead to an accumulation of cases with better defined epileptogenic zones.

show abstract

Disorders Due to Brain Damage and Dysfunction and to Physical Diseases (Excluding Neurocognitive Disorders)

Seidel

Buono

Città

et al. 2022

Textbook of Psychiatry for Intellectual Disability and Autism Spectrum Disorder

View full text Add to dashboard Cite

Visual hallucinations of autobiographic memory and asomatognosia: a case of epilepsy due to brain cysticercosis

Cited by 10 publications

References 34 publications

On the relationship between calcified neurocysticercosis and epilepsy in an endemic village: A large‐scale, computed tomography–based population study in rural Ecuador

On the relationship between calcified neurocysticercosis and epilepsy in an endemic village: A large‐scale, computed tomography–based population study in rural Ecuador

Localizing value of disturbances of self‐integration, depersonalization, and forced thinking: A systematic review

Disorders Due to Brain Damage and Dysfunction and to Physical Diseases (Excluding Neurocognitive Disorders)

Contact Info

Product

Resources

About