Visual impairment and vision‐related quality of life in the Early Manifest Glaucoma Trial after 20 years of follow‐up

Peters, Dorothea; Heijl, Anders; Brenner, Lena; Bengtsson, Bo

doi:10.1111/aos.12839

Cited by 83 publications

(81 citation statements)

References 37 publications

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“…about this tipping point and how it could be better quantified in the busy clinic. 54,67 This might need a rethink about the visual field requirements needed to cope with the real world instead of detecting fixed lights in the bowl of a perimeter.…”

Section: Discussionmentioning

confidence: 99%

A view on glaucoma—are we seeing it clearly?

Crabb

2015

Eye

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Successful clinical management of glaucoma should not simply be about control of intraocular pressure, but must equate to correct decisions about intensifying treatment when patients are at risk of developing 'visual disability'. Yet little is known about what visual field defects, at different stages of glaucoma, specifically affect patients' abilities to perform everyday visual tasks. One way to do this is to measure patient performance in tasks in a lab setting. Another way is to ask patients themselves. The latter can be revealing and demystify views about how patients perceive the world. This short commentary highlights some of the current research in this area.

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Section: Discussionmentioning

confidence: 99%

A view on glaucoma—are we seeing it clearly?

Crabb

2015

Eye

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“…[23] In fact, the very aim of glaucoma is not to keep IOP at optimum limits or to achieve perfect functional studies; it is to preserve the patient's autonomy and vision-related quality of life. [22,23] …”

Section: Discussionmentioning

confidence: 99%

Cost of glaucoma treatment in a developing country over a 5-year period

et al. 2016

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The aim of the study was to disclose a realistic estimate of primary open-angle glaucoma treatment, follow-up costs, and patients’ monthly glaucoma-economic burden in an ophthalmology hospital in Mexico City.Prospective survey of 462 primary open-angle glaucoma patients from 2007 to 2012 was carried out. Costs from visits, glaucoma follow-up studies, laser, and glaucoma surgical procedures were obtained from hospital pricings. Education, employment, and monthly income were interrogated. Total cost was divided into hypotensive treatment cost, nonpharmacologic treatment cost (laser and surgeries), and follow-up studies and consults. Average wholesale price for drugs analyzed was obtained from IMS Health data; monthly cost was calculated using: Monthly cost = ([average wholesale price/number of drops per eye dropper] × number of daily applications) × 30 days.Patients were classified according to their glaucoma severity, and data were analyzed based on monthly income (average annual exchange rate: 12.85 Mexican pesos = 1 USD).The mean age was 70 ± 10 years, women = 81%, elementary school = 39%, and unemployed = 53%. Low-income group = 266 patients (57%), 146 with mild glaucoma; moderate-income group = 176 patients (38%), 81 with mild glaucoma; high-income group = 20 patients (4.3%), 10 with mild glaucoma. Patients’ monthly average economic burden in glaucoma treatment: low-income patients = 61.5%, moderate-income patients = 19.5%, and high-income patients = 7.9%.Glaucoma-economic burden is substantial not only for health systems, but for the family and the patient. Therefore, screening plans for earlier diagnosis, and health policies that lessen the cost of disease management and increase adherence to treatment, and reduce the prevalence of blindness attributed to glaucoma are essential. These would improve quality of life, reduce personal and national expenditure, and help increase national economy.

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“…The QoL scores obtained with NEI-VFQ-25 ranged between 69.8 ± 1.9 and 90.7 ± 8.1 for glaucoma patients and between 51.8 ± 2.0 and 79.4 in AMD patients. 4,[14][15][16][17][18][19][20][21] These studies were mainly conducted in advanced forms of these diseases. 4,[14][15][16][17][18] There is little information about vision-specific QoL among patients with early stages of glaucoma and AMD.…”

Section: Introductionmentioning

confidence: 99%

“…4,[14][15][16][17][18] There is little information about vision-specific QoL among patients with early stages of glaucoma and AMD. [19][20][21] There is even less information about the QoL of comparable groups of glaucoma and primary open-angle glaucoma (POAG) patients, and the impact of involvement of different sites, that is, peripheral visual field vs central retina on QoL. The influence of visual disability to perform activities of daily living was generally assessed by tests that evaluated visual acuity and visual field sensitivity.…”

Section: Introductionmentioning

confidence: 99%

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Comparison of vision-related quality of life in primary open-angle glaucoma and dry-type age-related macular degeneration

Uğurlu

Altundal

Ekin

2016

Eye

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Purpose To compare quality of life (QoL) in patients with primary open-angle glaucoma (POAG) and dry-type age-related macular degeneration (AMD) with similar bestcorrected visual acuity. Methods Age-, sex-, and visual acuitymatched POAG and dry AMD patients were included in the study. Each patient performed 24-2 and 10-2 SITA standard visual field tests. Contrast sensitivity was evaluated with CSV-1000 HGT instrument. The 25 item National Eye Institute Visual Function Questionnaire (NEI-VFQ-25) was used to analyze QoL. Overall and subscale scores were converted to scores between 0 and 100, the higher scores indicating better visionrelated QoL. Results Overall NEI-VFQ-25 scores were 86.44 and 84.66 in glaucoma and AMD groups, respectively (P = 0.244). The highest scores were obtained in 'vision-related dependency' subgroup in glaucoma and 'color and peripheral vision' in AMD group, whereas the lowest scores were noted 'in peripheral vision' in both glaucoma and AMD patients. Glaucoma patients had significantly lower scores in ocular pain, color vision, and peripheral vision subgroups compared with the AMD group, whereas AMD patients had lower scores in near and distance vision activities, vision-related social activity, and dependency subgroups. Contrast sensitivity results and mean defect values showed correlation with NEI-VFQ-25 scores in both groups. Conclusions Glaucoma and AMD patients with similar visual acuity experienced similar overall impairment in QoL. However, glaucoma patients described more difficulty with peripheral vision and ocular pain, whereas AMD patients complained more about near and distance vision and dependency items.

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Visual impairment and vision‐related quality of life in the Early Manifest Glaucoma Trial after 20 years of follow‐up

Cited by 83 publications

References 37 publications

A view on glaucoma—are we seeing it clearly?

A view on glaucoma—are we seeing it clearly?

Cost of glaucoma treatment in a developing country over a 5-year period

Comparison of vision-related quality of life in primary open-angle glaucoma and dry-type age-related macular degeneration

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