1970
DOI: 10.1037/h0029465
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Visual perception in the retinal degenerate C3H mouse.

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Cited by 72 publications
(32 citation statements)
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“…Individual comparisons within these interactions showed that activity differences due to illumination level became reliable by 16 days of age for the 10-33 group 0, < .Ol) and by 20 days of age for the 14-33 group (p < .025), and remained reliable on all succeeding days. At all other ages, the Illumination X Test Day interactions were not significant, indicating that differences in activity due to illumination level were consistent over test days in agreement with Nagy and Misanin (1970).…”
Section: Activitysupporting
confidence: 79%
See 1 more Smart Citation
“…Individual comparisons within these interactions showed that activity differences due to illumination level became reliable by 16 days of age for the 10-33 group 0, < .Ol) and by 20 days of age for the 14-33 group (p < .025), and remained reliable on all succeeding days. At all other ages, the Illumination X Test Day interactions were not significant, indicating that differences in activity due to illumination level were consistent over test days in agreement with Nagy and Misanin (1970).…”
Section: Activitysupporting
confidence: 79%
“…The present study indicates lhat the pattern of decreasing activity over test days (Nagy & Misanin, 1970) is a function of both age and prior experience. For example, over the first 4 days of testing, mice beginning at 10 and 14 days of age showed increases in activity (both p's < .05), those beginning at 18 days of age showed a nonsignificant increase, whereas groups beginning at 22, 26, and 30 days of age showed decreases in activity (all p's < .05).…”
Section: Activitymentioning
confidence: 91%
“…Degeneration occurs so rapidly that only a thin layer of scattered rod photoreceptor cell bodies (lacking outer segments) remains at postnatal day 15, and the rod cell bodies disappear completely from the central retina by 36 d (Caley et al, 1972;Carter-Dawson et al, 1978), leading to blindness. Behavioral measurement to assess vision capabilities using the visual cliff task showed that rd1 mice were no longer capable of pattern recognition shortly after 40 d of age (Nagy and Misanin, 1970).…”
Section: Resultsmentioning
confidence: 99%
“…Evidence for a few remaining cone outer segments has also been reported in these mice using immunohistochemical probes that bind to cone outer segments (Pickard, Lemmon & Denoso, 1986). These photoreceptor losses result in a deterioration of visual function, as measured by ERG (Noell, 1958), single-cell recordings from the optic tectum (Drager & Hubel, 1978) and behavioural responses (Bonaventure & Karli, 1961;Nagy & Misanin, 1970). The threshold for inducing all of these visual responses increases dramatically (to sometimes immeasurable levels) in mice with degenerate retinae.…”
Section: Sensitivity To Stimulus Irradiancementioning
confidence: 99%