Visual Sensitivity and Epilepsy: A Proposed Terminology and Classification for Clinical and EEG Phenomenology

Trenité, Dorothee Kasteleijn‐Nolst; Guerrini, Renzo; Binnie, C.D.; Genton, Pierre

doi:10.1046/j.1528-1157.2001.30600.x

Cited by 135 publications

(42 citation statements)

References 79 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Photosensitivity or visual sensitivity (VS) is an abnormal sensitivity to light stimuli, detected usually with electroencephalography (EEG) as a paroxysmal reaction to Intermittent Photic Stimulation (IPS) (Quirk et al, 1995a;Shiraishi et al, 2001). This EEG response, elicited by IPS or by other visual stimuli of daily life, is called Photo Paroxysmal Response (PPR) (Fylan et al, 1999;Kasteleijn-Nolst Trenite´et al, 2001).…”

Section: Definition and Epidemiologymentioning

confidence: 99%

“…Rarely, the VS detected in normal individuals evolves into epilepsy (So et al, 1993;Verrotti et al, 2002). On the contrary, it is possible that the PPRs, detected in epileptic children, are an incidental finding, but more frequently the presence of PPRs is strictly related to that type of epilepsy (Kasteleijn-Nolst Trenite´et al, 2001).…”

Section: Definition and Epidemiologymentioning

confidence: 99%

See 1 more Smart Citation

Human photosensitivity: from pathophysiology to treatment

Verrotti

Salladini

et al. 2005

Euro J of Neurology

View full text Add to dashboard Cite

Photosensitivity is a condition detected on the electroencephalography (EEG) as a paroxysmal reaction to Intermittent Photic Stimulation (IPS). This EEG response, elicited by IPS or by other visual stimuli of daily life, is called Photo Paroxysmal Response (PPR). PPRs are well documented in epileptic and non-epileptic subjects. Photosensitivity rarely in normal individuals evolves into epilepsy. Photosensitive epilepsy is a rare refex epilepsy characterized by seizures in photosensitive individuals. The development of modern technology has increased the exposition to potential seizure precipitants in people of all ages, but especially in children and adolescents. Actually, videogames, computers and televisions are the most common triggers in daily life of susceptible persons. The mechanisms of generation of PPR are poorly understood, but genetic factors play an important rule. The control of visually induced seizures has, generally a good prognosis. In patients known to be visually sensitive, avoidance of obvious source and stimulus modifications are very important and useful to seizure prevention, but in the large majority of patients with epilepsy and photosensitivity antiepileptic drugs are needed.

show abstract

Section: Definition and Epidemiologymentioning

confidence: 99%

Section: Definition and Epidemiologymentioning

confidence: 99%

Human photosensitivity: from pathophysiology to treatment

Verrotti

Salladini

et al. 2005

Euro J of Neurology

View full text Add to dashboard Cite

show abstract

“…In de recent gepubliceerde richtlijnen betreffende de terminologie wordt een duidelijk onderscheid gemaakt tussen de verschillende soorten informatie (Kasteleijn, Guerrini, Binnie & Genton, 2001). Eenduidigheid in terminologie is daarbij gewenst.…”

Section: Definitiesunclassified

Epilepsie en visuele gevoeligheid

Trenité¹

2002

NEPR

View full text Add to dashboard Cite

Epilepsie en visuele gevoeligheid Dorothe´e Kasteleijn-Nolst TreniteÁ bstract Reeds in de Oudheid wist men dat flikkerend licht epileptische aanvallen kon opwekken. Alvorens een slaaf werd gekocht, werd gekeken of hij epileptische aanvallen kreeg door kwalijke dampen die opstegen uit asfalt of verbrande geitenlever, door het kijken naar een hond, een arend, een pottenbakkerswiel of naar zonlicht op dansende golven (Troch, 1975).

show abstract

“…The leading symptom is represented by myoclonus, a sudden, brief (shock-like), involuntary muscle jerk resulting from a burst of muscular activity (positive myoclonus) or from brief cessation of ongoing muscular activity (negative myoclonus) [4]. Myoclonic jerks may manifest at rest, when maintaining a posture or, more commonly, during action; moreover, they can be either spontaneous or provoked by specific stimuli such as intermittent light stimulation [5,6]. Many seizure types may occur in PMEs, the most common being generalized (especially tonicclonic and absence) seizures, although focal seizures may occur in some PMEs (i.e.…”

Section: Introductionmentioning

confidence: 99%

Update on Pharmacological Treatment of Progressive Myoclonus Epilepsies

Ferlazzo

Trenité²,

Haan

et al. 2018

CPD

View full text Add to dashboard Cite

Background Progressive myoclonus epilepsies (PMEs) are a group of rare inherited diseases featuring a combination of myoclonus, seizures and variable degree of cognitive impairment. Despite extensive investigations, a large number of PMEs remain undiagnosed. In this review, we focus on the current pharmacological approach to PMEs. Methods References were mainly identified through PubMed search until February 2017 and backtracking of references in pertinent studies. Results The majority of available data on the efficacy of antiepileptic medications in PMEs are primarily anecdotal or observational, based on individual responses in small series. Valproic acid is the drug of choice, except for PMEs due to mitochondrial diseases. Levetiracetam and clonazepam should be considered as the first add-on treatment. Zonisamide and perampanel represent promising alternatives. Phenobarbital and primidone should be reserved to patients with resistant disabling myoclonus or seizures. Lamotrigine should be used with caution due to its unpredictable effect on myoclonus. Avoidance of drugs known to aggravate myoclonus and seizures, such as carbamazepine and phenytoin, is paramount. Psychiatric (in particular depression) and other comorbidities need to be adequately managed. Although a 3- to 4-drug regimen is often necessary to control seizures and myoclonus, particular care should be paid to avoid excessive pharmacological load and neurotoxic side effects. Target therapy is possible only for a minority of PMEs. Conclusions Overall, the treatment of PMEs remains symptomatic (i.e. pharmacological treatment of seizures and myoclonus). Further dissection of the genetic background of the different PMEs might hopefully help in the future with individualised treatment options.

show abstract

Visual Sensitivity and Epilepsy: A Proposed Terminology and Classification for Clinical and EEG Phenomenology

Cited by 135 publications

References 79 publications

Human photosensitivity: from pathophysiology to treatment

Human photosensitivity: from pathophysiology to treatment

Epilepsie en visuele gevoeligheid

Update on Pharmacological Treatment of Progressive Myoclonus Epilepsies

Contact Info

Product

Resources

About