Visual surround suppression at the neural and perceptual levels

Li, Yang; Dai, Weifeng; Wang, Tian; Wu, Yujie; Dou, Fei; Xing, Dajun

doi:10.1007/s11571-023-10027-3

Cited by 3 publications

(1 citation statement)

References 171 publications

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“…The center–surround suppression may be closely related to information received by neurons, including from feedforward, horizontal, and feedback connections [ 32 , 33 ]. Indeed, the OT is a multi-stratified structure and contains 15 alternating cell and fiber layers [ 34 , 35 ].…”

Section: Discussionmentioning

confidence: 99%

Dynamic Nonlinear Spatial Integrations on Encoding Contrasting Stimuli of Tectal Neurons

Huang,

Hu,

Zhao

et al. 2024

Animals

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Animals detect targets using a variety of visual cues, with the visual salience of these cues determining which environmental features receive priority attention and further processing. Surround modulation plays a crucial role in generating visual saliency, which has been extensively studied in avian tectal neurons. Recent work has reported that the suppression of tectal neurons induced by motion contrasting stimulus is stronger than that by luminance contrasting stimulus. However, the underlying mechanism remains poorly understood. In this study, we built a computational model (called Generalized Linear-Dynamic Modulation) which incorporates independent nonlinear tuning mechanisms for excitatory and inhibitory inputs. This model aims to describe how tectal neurons encode contrasting stimuli. The results showed that: (1) The dynamic nonlinear integration structure substantially improved the accuracy (significant difference (p < 0.001, paired t-test) in the goodness of fit between the two models) of the predicted responses to contrasting stimuli, verifying the nonlinear processing performed by tectal neurons. (2) The modulation difference between luminance and motion contrasting stimuli emerged from the predicted response by the full model but not by that with only excitatory synaptic input (spatial luminance: 89 ± 2.8% (GL_DM) vs. 87 ± 2.1% (GL_DMexc); motion contrasting stimuli: 87 ± 1.7% (GL_DM) vs. 83 ± 2.2% (GL_DMexc)). These results validate the proposed model and further suggest the role of dynamic nonlinear spatial integrations in contextual visual information processing, especially in spatial integration, which is important for object detection performed by birds.

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Section: Discussionmentioning

confidence: 99%

Dynamic Nonlinear Spatial Integrations on Encoding Contrasting Stimuli of Tectal Neurons

Huang,

Hu,

Zhao

et al. 2024

Animals

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Alterations in center-surround contrast suppression in patients with major depressive disorder

Nickel,

Heinrich,

Beringer

et al. 2024

Sci Rep

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Previous pattern electroretinogram studies indicate reduced retinal contrast gain in patients with a major depressive disorder (MDD) which may contribute to alterations in visual perception. In line, psychophysical investigations reported elevated contrast thresholds in MDD. This study aims to gain insights into higher-level processing of visual information in MDD by evaluating contrast suppression. We examined contrast suppression of 21 MDD patients and 23 healthy controls (HC) using four different stimulus conditions (spatial frequencies 6.3 and 12.6 cpd at 30% and 60% background contrast) in a psychophysical test. Participants were instructed to adjust perceived contrasts between two vertical target patches, embedded in a horizontally or vertically oriented grid background. With finer stimulus gratings, MDD patients exhibited less contrast suppression compared to HC, particularly when the stimulus contrast was high (p = 0.006; MDD vs. HC = − 45%). Contrast suppression in the HC group was significantly reduced for the coarse compared to the fine grating, while contrast suppression scores in MDD did not change with the spatial properties of the stimulus. The reduced contrast suppression in patients with MDD supports the hypothesis of altered dopaminergic neurotransmission and could be attributed to alterations in the retinal receptive fields or in dysfunctional adaptation mechanisms in depression.

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Context‐dependent orientation discontinuity encoding by gamma rhythms in mouse primary visual cortex

Liao,

Gong,

Sun

et al. 2024

The Journal of Physiology

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Through the modulation of its surround, an identical visual stimulus can be perceived as more or less salient, allowing it to either stand out or seamlessly integrate with the rest of the visual scene. Gamma rhythms are associated with processing stimulus features across extensive areas of the visual field. Consistent with this concept, the magnitude of visually induced gamma rhythm depends on how well stimulus features aligned both within and outside the classical receptive field (CRF) at the recording site. However, there still exists some uncertainty regarding the encoding of context‐modulated orientation discontinuity by gamma rhythms. To address this concern, we conducted extracellular recordings in layers II/III and IV of area V1 using lightly anaesthetized mice to investigate the gamma tuning for stimuli with orientation discontinuity. Our study revealed that gamma rhythms exhibit a preference for stimuli with orientation discontinuity similar to the spiking responses observed in V1, which contradicts the findings of previous studies. Furthermore, the gamma tuning of discontinuous orientations exhibits a moderate correlation with spike tuning and a positive correlation with the strength of surround suppression. Therefore, our study suggests a close association between gamma tuning and nearby spiking tuning; additionally, it highlights the connection between the encoding of visual features by gamma rhythms and functional architecture, as well as neural signal integration. imageKey points Visual context modulates the gamma rhythms in the primary visual cortex. Discontinuous orientation elicits significantly enhanced gamma rhythms compared to the iso‐orientation stimulus. The gamma tuning of discontinuous orientations exhibits a moderate correlation with spike tuning. Gamma tuning of orientation discontinuity exhibits a positive correlation with the strength of surround suppression.

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Visual surround suppression at the neural and perceptual levels

Cited by 3 publications

References 171 publications

Dynamic Nonlinear Spatial Integrations on Encoding Contrasting Stimuli of Tectal Neurons

Dynamic Nonlinear Spatial Integrations on Encoding Contrasting Stimuli of Tectal Neurons

Alterations in center-surround contrast suppression in patients with major depressive disorder

Context‐dependent orientation discontinuity encoding by gamma rhythms in mouse primary visual cortex

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