Visualisation of the visual system

Thompson, Benjamin

doi:10.1111/opo.12586

Cited by 1 publication

(1 citation statement)

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“…Optical coherence tomography (OCT) en face visualisation of hyporeflectivity in the retinal nerve fibre layer (RNFL) is an appealing alternative for effectively guiding perimetric sampling for several reasons. These include the spatial detail in the pattern of RNFL hyporeflectivity, 13,14 as well as the limited contribution of non-fibre component to the reflectance signature assessed by the OCT en face visualisation of the RNFL. 15 Recent studies have found that the spatial pattern of the RNFL hyporeflectivity seen in the en face images was also seen in results from static perimetry.…”

Section: Introductionmentioning

confidence: 99%

Functional characteristics of glaucoma related arcuate defects seen on OCT en face visualisation of the retinal nerve fibre layer

Ashimatey

King

Swanson

2021

Ophthalmic Physiologic Optic

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Purpose To assess continuity of perimetric defects corresponding to arcuate defects seen on optical coherence tomography (OCT) en face reflectance images of the retinal nerve fibre layer (RNFL) in patients with glaucoma. Methods Seven patients with glaucoma who had arcuate structural defects on OCT RNFL en face images were recruited. Static suprathreshold stimuli were presented along different meridians to localise perimetric defects in the corresponding hemifield. Then two contrasts, one 6 dB greater than the other, were used with kinetic perimetry to assess the slope of the defect. Findings with kinetic and 24‐2 perimetry were compared. Results Static perimetry found that regions of perimetric abnormality spatially corresponded with the regions of en face RNFL hyporeflectivity. Kinetic perimetry found that the slopes of the edges of the defects ranged from 3–12 dB degree−1, and that the functional abnormalities were continuous with the physiologic blind spot even when the 24‐2 protocol only showed paracentral defects. Conclusions Perimetric abnormalities and arcuate RNFL en face defects were spatially correspondent. Perimetric testing guided by OCT en face reflectance images can reveal greater functional detail of glaucomatous abnormality than 24‐2 testing.

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Section: Introductionmentioning

confidence: 99%