Visualization of mucosal vasculature with narrow band imaging: a theoretical study

Wang, Quanzeng; Le, Du; Ramella‐Roman, Jessica C.; Pfefer, Joshua

doi:10.1117/12.906817

Cited by 4 publications

(4 citation statements)

References 31 publications

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“…The scattering coefficient was calculated with equation (2). Thus, the error from the overestimation of the total transmission should be nearly negligible.…”

Section: Scattering Coefficientmentioning

confidence: 99%

“…These missing optical properties of all layers can lead to a wrong calculation in further investigations. In particular, Wang et al [2] investigating NBI with Monte-CarloSimulations could not do a precise simulation because m s and g are missing for all layers of the esophagus. Due to their usage of only m a and m 0 s for the simulation of small volumes, this approach can lead to systematic errors because for small distances the right phase-function is important [9,10].…”

Section: Introductionmentioning

confidence: 99%

“…This includes light dosimetry calculations for PhotoDynamic Therapy (PDT) [1] or the evaluation of the factors that affect the performance of Narrow Band Imaging (NBI) [2]. For developing new optical based clinical techniques, tissue phantoms are often used in experiments to prove concepts and perform optimizations of new diagnostic techniques [3,4].…”

Section: Introductionmentioning

confidence: 99%

“…On the one hand, this allows a correct simulative evaluation of NBI [2] with lower potential systematic errors present in the actual evaluations. Also the treatment-planning of PDT can be more precise because the scattering of the incident light can be considered with a higher precision.…”

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confidence: 99%

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Measurement of optical properties of pig esophagus by using a modified spectrometer set‐up

Hohmann

Lengenfelder

Kanawade

et al. 2017

Journal of Biophotonics

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Optical properties (m a , m s and g) of certain human tissue types such as skin and blood have been very well investigated. However until today, for internal body organs such as the esophagus they are not well characterized. For ex-vivo measurements "Inverse Adding Doubling" (IAD) and Inverse Monte-Carlo-Simulation (IMCS) are state of the art. Both methods need the measurement of the collimated transmission. Current methods lack a proper way of measuring the collimated transmission. Hence, this measurement of the g-factor has a systematic error. Therefore, for the measurement of the collimated transmission, a new approach has been developed and evaluated with intralipid. Finally, the optical properties of mucosa, sub mucosa, muscularis and adventitia of pig esophagus tissue are calculated with IAD. The results are promising and in agreement with published literature.

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“…The scattering coefficient was calculated with equation (2). Thus, the error from the overestimation of the total transmission should be nearly negligible.…”

Section: Scattering Coefficientmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

mentioning

confidence: 99%

See 2 more Smart Citations

Measurement of optical properties of pig esophagus by using a modified spectrometer set‐up

Hohmann

Lengenfelder

Kanawade

et al. 2017

Journal of Biophotonics

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Narrow band imaging for the diagnosis of head and neck squamous cell carcinoma: A systematic review

2016

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Narrow band imaging (NBI) is reported to improve the diagnostic accuracy of head and neck cancers. The purpose of this review was to evaluate the diagnostic accuracy of NBI in the literature. A systematic review was performed in PubMed, Web of Knowledge, and the Cochrane Library until March 2015. Two reviewers independently assessed articles and extracted data. Meta-analyses were performed in MetaDisc 1.6. Five hundred seventeen studies were identified and 17 were included in this study. Combined use of NBI and white light imaging (WLI) showed high diagnostic accuracies for primary, recurrent, and nasopharyngeal lesions. Methodological heterogeneity exists and meta-analyses were only appropriate for cancers of unknown primary (CUP) in which NBI performed on 115 patients across 4 studies demonstrated high sensitivity (74.1%; 95% confidence interval [CI] = 52.5% to 100%) and specificity (94.1%; 95% CI = 23.7% to 100%). NBI may further help identify lesions in CUP not seen by positron emission tomography (PET)-CT. NBI offers a high level of diagnostic accuracy for head and neck cancers. © 2016 Wiley Periodicals, Inc. Head Neck 38: E2358-E2367, 2016.

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In‐vivo multispectral video endoscopy towards in‐vivo hyperspectral video endoscopy

Hohmann

Kanawade

Klämpfl

et al. 2016

Journal of Biophotonics

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For in‐vivo diagnostics of cancer and pre‐cancer in the stomach, there is no endoscopic procedure offering both high sensitivity and high specificity. Our data suggest that multispectral or hyperspectral imaging may be helpful to solve this problem. It is successfully applied to the detection and analysis of easily reachable carcinomas, ex‐vivo samples of hollow organ mucosal carcinomas and also histological samples. An endoscopy system which allows flexible multispectral videoendoscopy for in‐vivo diagnostics has so far been unavailable. To overcome this problem, we modified a standard Olympus endoscopy system to conduct in‐vivo multispectral imaging of the upper GI tract. The pilot study is performed on 14 patients with adeno carcinomas in the stomach. For analysis, Support Vector Machine with linear and Gaussian Kernel, AdaBoost, RobustBoost and Random‐Forest‐walk are used and compared for the data classification with a leave‐one‐out strategy. The margin of the carcinoma for the training of the classifier is drawn by expert‐labeling. The cancer findings are cross‐checked by biopsies. We expect that the present study will help to improve the further development of hyperspectral endoscopy and to overcome some of the problems to be faced in this process.

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Visualization of mucosal vasculature with narrow band imaging: a theoretical study

Cited by 4 publications

References 31 publications

Measurement of optical properties of pig esophagus by using a modified spectrometer set‐up

Measurement of optical properties of pig esophagus by using a modified spectrometer set‐up

Narrow band imaging for the diagnosis of head and neck squamous cell carcinoma: A systematic review

In‐vivo multispectral video endoscopy towards in‐vivo hyperspectral video endoscopy

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