“…In times where software is abundant and accessible, the focus of introductory statistics courses should be primarily on statistical reasoning, as made most clear by computational, simulation-based methods such as bootstrap, permutation tests, simulation-based sample size calculation, ..., on concepts of bias (e.g., selection bias, confounding bias) and imprecision, on the translation of scientific questions into statistical estimands, on key assumptions linked to study design (e.g., independence assumptions), on flexible (statistical or machine) learning methods for prediction, which form a cornerstone of the methods of Section 3, ... For the smaller minority of students who are mathematically-minded and/or wish to engage in methods development, a core training in asymptotic statistics obviously remains indispensable. I believe that a central focus of such training should lie on nonparametric estimation and efficiency theory (Bickel et al, 1993;Kennedy, 2016;Fisher and Kennedy, 2020).…”