Visuospatial versus visuomotor activity in the premotor and prefrontal cortex of a primate

Abstract

We thank Mr. William Burriss for his assistance. We also thank Dr. Eilon Vaadia for his critical reading of the manuscript. G.dP.

The role of prefrontal cortex in working-memory capacity, executive attention, and general fluid intelligence: An individual-differences perspective

“…K. Miller, Li, & Desimone, 1993). Such disruption is not seen in delayresponsive dPFC cells (di Pellegrino & Wise, 1993a, 1993bE. K. Miller et al, 1996).…”

Generalizing the dynamic field theory of spatial cognition across real and developmental time scales

“…On one hand, several characteristics of dynamic activation patterns in our model reflect processes that have been linked to different cortical areas. For instance, the selfsustaining working memory peaks discussed here can survive intervening presentations of stimuli, a characteristic of spatial representations in dorso-lateral prefrontal cortex (di Pellegrino & Wise, 1993). By contrast, although activation patterns in our perceptual field can be sustained under some conditions (see the generation of a "different" response in Fig.…”

“…For instance, it is likely that the development of the dorso-lateral prefrontal cortex plays a central role in the tasks we discuss because this region of cortex is heavily involved in the on-line maintenance of spatial information (Awh, et al, 1999;di Pellegrino & Wise, 1993;Kessels, Postma, Wijnalda & de Haan, 2000;Nelson, et al, 2000). Moreover, the development of the prefrontal cortex shows a protracted course that continues into the postadolescent years (Gogtay, et al, 2004;Rakic, 1995;Sowell, Thompson, Tessner & Toga, 2001).…”

“…Importantly, this link has been tested in both motor cortex and visual cortex (Bastian, et al, 1998;Bastian, et al, 2003;. There is also evidence that space is neurally represented across continuous, metric feature dimensions, though it is important to emphasis that this topography is functional rather than anatomical in most cortical areas (di Pellegrino & Wise, 1993;Georgopoulos, Lurito, Petrides, Schwartz & Massey, 1989;Georgopoulos, Taira & Lukashin, 1993;Wilson, Scalaidhe & Goldman-Rakic, 1993). Similarly, there is strong evidence from studies of cortical neurons for the basic local excitation / lateral inhibition form of neural interaction used in dynamic field models (e.g., Durstewitz, Seamans & Sejnowski, 2000).…”

Decoding Movement Intent From Human Premotor Cortex Neurons for Neural Prosthetic Applications

“…Andersen and colleagues demonstrated that signals in parietal cortex of monkeys could provide a command that signaled upcoming movement intent for specific movement directions and expected reward value (Musallam et al, 2004). Large extents of frontal cortex outside of MI are active in movement planning (Kurata & Wise, 1988;Fu et al, 1995;Toni et al, 1999;Crammond & Kalaska, 2000;Harrington et al, 2000) and movement intent (di Pellegrino & Wise, 1993;Rao, et al, 1997;Kalaska & Crammond, 1995;Crammond & Kalaska, 2000), suggesting that useful movement signals may be available in these areas as well. Indeed, premotor and primary motor areas in the monkey provide different types of movement information .…”