Visusevaluierung in einer historischen Kohorte von 137 okkludierten Patienten, 30 - 35 Jahre nach Ende der Okklusionsbehandlung

Simonsz-Tòth, Brigitte; Loudon, Sjoukje E.; Saar, Hanneke van Kempen-du; Graaf, Elizabeth S. van de; Groenewoud, Johanna H.; Simonsz, Huib

doi:10.1055/s-2006-927209

Cited by 11 publications

(7 citation statements)

References 13 publications

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“…Die Pathogenese der exzentrischen Fixation ist bis heute nicht genau geklärt [9], sie kommt aber sowohl bei Suppressionsamblyopien bei Strabismus als auch bei Deprivationsamblyopien [3,6,9,14] vor. Die langfristige schlechte Visusprognose bei exzentrischer oder ehemals exzentrischer Fixation ist belegt [24,26]. In den 60er-Jahren wurde nachgewiesen, dass die Okklusion des führenden Auges der des exzentrisch fixierenden, sogenannte inverse Okklusion, überlegen ist [13,15,16].…”

Section: Korrelation Zu Hyperopie Und Anisometropie Astigmatismusunclassified

Ergebnisse später Therapie von exzentrischer Fixation bei verschiedenen Amblyopieformen

Gusek-Schneider¹

2010

Klin Monatsbl Augenheilkd

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The typical age at the time of the first visit to the clinic in this study was around 5 years for most of the excentric fixations investigated. This requires greater intervention of occlusion therapy. In this study, the patients with anisomyopia and infantile esotropia showed the best success rates, and the children with microstrabismus showed the poorest success rates. The fixations close to the papilla, temporal macular wall, and over the foveola were shown to be favourable in relation to the prognosis. With microstrabism, a quasi-burned in nasal excentric fixation with binocularity dominated the unsuccessful attempts. With the primary forms of esotropia, a highly hyperopic amblyopic eye is unfavourable in relation to the prognosis.

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Section: Korrelation Zu Hyperopie Und Anisometropie Astigmatismusunclassified

Ergebnisse später Therapie von exzentrischer Fixation bei verschiedenen Amblyopieformen

Gusek-Schneider¹

2010

Klin Monatsbl Augenheilkd

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“…Of these 471 persons, 203 could be contacted 30–35 years after treatment. Of these 203 persons, 173 completed the A&SQ in 2002 [ 3 ], and 137 of these were orthoptically re-examined in 2003 [ 11 , 12 ]. The 173 persons were contacted again for the purpose of the present study and were invited to complete the AS-20, which was sent to them, accompanied by a letter to inform about and obtain consent to participate in the study.…”

Section: Methodsmentioning

confidence: 99%

Differences in quality-of-life dimensions of Adult Strabismus Quality of Life and Amblyopia & Strabismus Questionnaires

Graaf

Borsboom

Sterre

et al. 2017

Graefes Arch Clin Exp Ophthalmol

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PurposeThe Adult Strabismus Quality of Life Questionnaire (AS-20) and the Amblyopia & Strabismus Questionnaire (A&SQ) both measure health-related quality of life in strabismus patients. We evaluated to what extent these instruments cover similar domains by identifying the underlying quality-of-life factors of the combined questionnaires.MethodsParticipants were adults from a historic cohort with available orthoptic childhood data documenting strabismus and/or amblyopia. They had previously completed the A&SQ and were now asked to complete the AS-20. Factor analysis was performed on the correlation-matrix of the combined AS-20 and A&SQ data to identify common underlying factors. The identified factors were correlated with the clinical variables of angle of strabismus, degree of binocular vision, and visual acuity of the worse eye.ResultsOne hundred ten patients completed both questionnaires (mean age, 44 years; range, 38–51 years). Six factors were found that together explained 78% of the total variance. The factor structure was dominated by the first four factors. One factor contained psychosocial and social-contact items, and another factor depth-perception items from both questionnaires. A third factor contained seven items—only from the AS-20—on eye strain, stress, and difficulties with reading and with concentrating. A fourth factor contained seven items—only from the A&SQ—on fear of losing the better eye and visual disorientation, specific for amblyopia. Current visual acuity of the worse eye correlated with depth-perception items and vision-related items, whereas current binocular vision correlated with psychosocial and social-contact items, in 93 patients.ConclusionsFactor analysis suggests that the AS-20 and A&SQ measure a similar psychosocial quality-of-life domain. However, functional problems like avoidance of reading, difficulty in concentrating, eye stress, reading problems, inability to enjoy hobbies, and need for frequent breaks when reading are represented only in the AS-20. During the development of the A&SQ, asthenopia items were considered insufficiently specific for strabismus and were excluded a priori. The patients who generated the items for the AS-20 had, in majority, adulthood-onset strabismus and diplopia and were, hence, more likely to develop such complaints than our adult patients with childhood-onset strabismus and/or amblyopia.

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“…One hundred and seventy four of these had filled out the A&SQ [7, 8]. One hundred and thirty seven of them had been orthoptically re-examined by orthoptists [6, 10]. The historic cohort formed an almost non-select sample of all patients occluded at that time, because all children with insufficient visual acuity or strabismus from the entire region around Purmerend had been referred to a single practicing ophthalmologist and orthoptist at the time.…”

Section: Methodsmentioning

confidence: 99%

“…These indicated that the historic cohort was representative for the children with amblyopia within the entire population in the region at that time. Of the children born in this region in 1965, 1966 and 1967, 4.8 % had received occlusion therapy [10]. …”

Section: Methodsmentioning

confidence: 99%

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Utility analysis of disability caused by amblyopia and/or strabismus in a population-based, historic cohort

Graaf

Saar

Looman

et al. 2010

Graefes Arch Clin Exp Ophthalmol

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BackgroundAmblyopia (prevalence 3.4%) is in principle treatable, but approximately one quarter of children do not reach reading acuity in the amblyopic eye. Adults with persistent amblyopia and/or strabismus experience a decrease in quality of life. This was now quantified by patient-perceived utility values.MethodsSubjects were born 1962–1972 and had been treated by occlusion therapy for amblyopia by one orthoptist 30–35 years ago. All children in Waterland with amblyopia and/or strabismus had been referred to this orthoptist. Utilities were derived by methods of time trade-off, TTO (lifetime traded against perfect vision) and standard gamble, SG (death risk accepted for perfect vision). Most troubling eye disorder (low acuity of the amblyopic eye, lacking stereopsis or strabismus) was chosen and ranked among nine chronic disorders according to the subject’s perceived severity.ResultsFrom 201 patients that could be contacted 35 years after occlusion therapy — out of 471 who had been occluded — 135 were included: 17 could not be reached, 34 refused, and 15 had other reasons to not participate. Mean age was 40.86 years; 53% were male. Seventy percent were willing to trade lifetime according to the TTO method; its mean (log) utility was 0.963, i.e., a decrease in quality of life of 3.7%. Thirty-seven percent accepted death risk according to the SG method; its mean utility was 0.9996. TTO outcomes correlated with current near and distance visual acuity. Low acuity of the amblyopic eye, chosen as most troubling eye disorder, ranked slightly less severe than tooth decay.ConclusionAmblyopia and/or strabismus patients had a slightly decreased utility. The decrease is small but still important in the cost-effectiveness of vision screening because these conditions occur very frequently.

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Visusevaluierung in einer historischen Kohorte von 137 okkludierten Patienten, 30 - 35 Jahre nach Ende der Okklusionsbehandlung

Abstract: A decrease in visual acuity after cessation of occlusion therapy occurred in patients with a combined cause of amblyopia or with an increase in anisohypermetropia.

Cited by 11 publications

References 13 publications

Ergebnisse später Therapie von exzentrischer Fixation bei verschiedenen Amblyopieformen

Ergebnisse später Therapie von exzentrischer Fixation bei verschiedenen Amblyopieformen

Differences in quality-of-life dimensions of Adult Strabismus Quality of Life and Amblyopia & Strabismus Questionnaires

Utility analysis of disability caused by amblyopia and/or strabismus in a population-based, historic cohort

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