Vitamin B₁₂deficiency in Indian infants and children

Vitamin B12 Deficiency Disguised As Hemolytic Anemia: A Case Presentation

“…Symptoms of severe B12 deficiency in infancy include lethargy, apathy with little interest in their surroundings, failure to thrive, convulsions, and developmental delays, which were consistent with the clinical picture of our patient at the time of presentation as he had global developmental delays with lethargy and hypoactivity that persisted even after his hemoglobin normalized [ 5 ].…”

“…During infancy, cobalamin deficiency is a result of low maternal cobalamin stores during pregnancy, resulting in low liver stores in the infant, and maternal deficiencies after delivery will result in low contents of cobalamin in breast milk leading to low supplies to the already deficient infant who might become symptomatic as soon as two to 12 month of age [ 3 , 4 ]. Consequently, it is more common in exclusively breastfed infants by mothers with a strict vegetarian diet or who do not have access to food of animal origin for socio-economic reasons and is commonly described in India and Pakistan [ 5 , 6 ]. The patient that we describe likely had cobalamin deficiency from a lack of any animal foods in his diet and was solely dependent on breast milk for his nutrition.…”

The Effect of Early Pediatric Rehabilitation in an Infant With Vitamin B12 Deficiency Associated With Developmental Delay: A Case Report

“…As the condition progresses, it affects neurodevelopment, causing infants to lag behind their peers and experience anemia and skin pigmentation changes. If left untreated, multiple symptoms of developmental regression may occur, sometimes triggered by intercurrent illness [4][5][6]. The infants may appear lethargic but become irritable when disturbed.…”

Diet Quality Influences the Occurrence of Food Aversions in Women Undergoing Adjuvant Chemotherapy for Breast Cancer

“…Although the association between adjuvant chemotherapy and food aversions is already well understood [ 7 ], gustatory and olfactory alterations, responsible for food aversions, are also caused by nutritional deficiencies, mainly zinc [ 8 ] and vitamin B 12 [ 9 ]. In addition, one of the main causes of food aversions in response to adjuvant chemotherapy is increased oxidative stress [ 10 ].…”