Vitamin C and Skin

Sugiura, Keiji; Sugiura, Mariko

doi:10.4172/2155-9554.1000444

Cited by 4 publications

(5 citation statements)

References 47 publications

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“…Vitamin C has a role in stratum corneum formation and epithelial differentiation in general [22]. Vitamin C can lighten the skin by reducing melanin through the tyrosinase enzyme activity and oxidized dopaquinone in the synthetic melanin pathway [22], [23]. Vitamin E is one of the active substances that has benefits in preventing aging because of its photoprotective mechanism, tightening, hydrating, and increasing elasticity.…”

Section: A Vitamin C Level Of Garciniacowa Fruit Flesh Extractmentioning

confidence: 99%

Determination of Vitamin C, Vitamin A and Flavonoid Levels in Garcinia cowa Roxb Fruit Flesh Extract

Minerva¹,

Hefni²

2022

International Journal on Advanced Science, Engineering and Information Technology

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Garcinia cowa Roxb is a plant used as traditional medicine containing antioxidant activity. Plant extracts with antioxidant activity are often used as bioactive ingredients in anti-aging cosmetics. Studies on bioactive compounds and the use of this plant in cosmeceuticals have yet to be widely reported. This study aims to determine and analyze the levels of flavonoids, vitamins C, and vitamin A in G. cowa fruit flesh extract. These three compounds are bioactive ingredients that are beneficial in reducing the symptoms of photoaging on the skin. The G. cowa used in this study was obtained from Tampunik Kambang, Pesisir Selatan Regency, and was extracted by maceration method using 96% ethanol. The testing of vitamin C levels in the extract of G. cowa fruit flesh was carried out through High-Performance Liquid Chromatography (HPLC) method using a UV detector with a wavelength of 264 nm. Quantitative HPLC analysis was carried out based on the resulting peak area data from the chromatogram. Vitamin A and flavonoid levels were measured using ultraviolet-visible spectrophotometry (UV-VIS) at maximum wavelengths of 286 and 429 nm. The results show that the levels of vitamin C and vitamin A in G. cowa was 151.4 mg/100g extract and 1.23 g 100g extract, while the flavonoid level was 69.5 mg/100g extract. The level of vitamins C, vitamin A, and flavonoids in G. cowa can contribute to natural bioactive substances and can be developed further into anti-aging cosmeceutical products.

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Section: A Vitamin C Level Of Garciniacowa Fruit Flesh Extractmentioning

confidence: 99%

Determination of Vitamin C, Vitamin A and Flavonoid Levels in Garcinia cowa Roxb Fruit Flesh Extract

Minerva¹,

Hefni²

2022

International Journal on Advanced Science, Engineering and Information Technology

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“…It is a generous donor of electrons; therefore, it is aiding in the scavenging mechanism [10]. Vitamin C is known as ascorbic acid (AA), which is the reduced form of Vitamin C [19]. It is essential for the normal physiological functions of the body [20].…”

Section: Introductionmentioning

confidence: 99%

The Effects of Zinc and Vitamin C Supplementation on the Glycemic Profile in Type 2 Diabetic Patients

Aruoah

Al-Jowari

2022

eijs

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Diabetes mellitus (DM) is the most common endocrine disorder and one of the highly progressive diseases which is indicated by high blood sugar (hyperglycemia). The present study aims to study the effects of treatment with zinc and vitamin C on glycemic profile [fasting blood sugar (FBS), glycated haemoglobin (HbA1C), and insulin hormone level] in type 2 diabetic patients. The study included 56 diabetic patients [30 without foot ulcers (15 without zinc and vitamin C supplements, 15 with zinc and vitamin C supplements) and 26 with foot ulcers (15 without zinc and vitamin C supplements, 11 with zinc and vitamin C supplements)]. Also, 15 healthy persons were used as a control group. The patients were enrolling to Azadi Teaching Hospital and Kirkuk General Hospital/ Kirkuk city/ Iraq; their ages ranged from 30 to 60 years and weights ranged from 70 to 90 kilogram. Blood samples were collected from the studied subjects to determine fasting blood sugar (FBS) concentration, glycated haemoglobin (HbA1C) level, and insulin hormone level. Zinc and vitamin C supplements were used for four weeks by a group of the patients. The results showed highly significant (P≤0.01) decreases in the values of FBS, HbA1C, and insulin in diabetic patients treated with supplements (both with and without foot ulcers) compared with diabetic patients without supplements (both with and without foot ulcers). It can be concluded that zinc and vitamin C supplements have improving impacts on patients with diabetes mellitus by improving glycemic profile parameters, such as FBS, HbA1C, and insulin.

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“…Vitamin C is used in the treatment of melasma; it acts on melanin especially oxidized type and decreases this dark melanin by acting on copper ions, dopaquinone, and inhibiting tyrosinase enzyme, thus inhibiting melanogenesis 12 . Also, it has a photoprotection effect, anti‐inflammatory effect, and immuno‐modulatory effect; moreover, it stimulates collagen remodeling and production 13,14 …”

Section: Introductionmentioning

confidence: 99%

“…12 Also, it has a photoprotection effect, anti-inflammatory effect, and immuno-modulatory effect; moreover, it stimulates collagen remodeling and production. 13,14 1. 1…”

mentioning

confidence: 99%

Efficacy and Safety of tranexamic acid versus vitamin c after microneedling in treatment of melasma: Clinical and Dermoscopic study

Attar

Doghaim

Far

et al. 2021

J of Cosmetic Dermatology

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Background Melasma is a common acquired symmetrically distributed hyperpigmented macules of sun‐exposed skin. Skin microneedling acts as a transdermal delivery system that facilitates the penetration of lightening agents to deeper layers of skin. Objective Clinical and dermoscopic evaluation of the efficacy and safety of topical tranexamic acid versus topical vitamin C after microneedling for melasma treatment. Patients and Methods Twenty patients with facial melasma were enrolled in a split‐face prospective, randomized uncontrolled study. The right side of the face was treated with topical tranexamic acid after dermapen microneedling, while the left side of the face was treated with topical vitamin C after dermapen microneedling. Sessions were done every 2 weeks for 6 sessions. The Hemi‐MASI score and dermoscopic examination before and after treatment were done. Results Hemi‐MASI score was reduced after treatment on both sides of the face, besides improvement of the pigmented lesions showed by dermoscopy on both sides and improvement of the vascular component on the tranexamic acid treated side. Conclusion Topical tranexamic acid or vitamin C application after dermapen microneedling was an effective and safe technique in melasma treatment with minimal side effects, and vascular component improvement by tranexamic acid.

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Vitamin C and Skin

Cited by 4 publications

References 47 publications

Determination of Vitamin C, Vitamin A and Flavonoid Levels in Garcinia cowa Roxb Fruit Flesh Extract

Determination of Vitamin C, Vitamin A and Flavonoid Levels in Garcinia cowa Roxb Fruit Flesh Extract

The Effects of Zinc and Vitamin C Supplementation on the Glycemic Profile in Type 2 Diabetic Patients

Efficacy and Safety of tranexamic acid versus vitamin c after microneedling in treatment of melasma: Clinical and Dermoscopic study

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