Vitamin C-reduced graphene oxide improves the performance and stability of multimodal neural microelectrodes

Murphy, Brendan B.; Apollo, Nicholas V.; Unegbu, Placid; Posey, Tessa; Rodriguez-Perez, Nancy; Hendricks, Quincy; Cimino, Francesca; Richardson, Andrew G.; Vitale, Flavia

doi:10.1016/j.isci.2022.104652

Cited by 7 publications

(6 citation statements)

References 125 publications

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“…First, an aqueous dispersion of GO (4 mg/mL) was vortexed (5 min) with l -ascorbic acid (LAA) solution (50 mM) in a 1:1 volume ratio. Afterward, the GO/LAA solution (120 μL) was uniformly dispensed onto previously prepared Ti 3 CNT x thin films and spin-coated at 2000 rpm for 30 s. The previous study demonstrated that LAA is a safe, cost-effective, and efficient reducing agent . After the spinning, the sample was placed on a hot plate at 150 °C for 20 min to complete the in situ reduction process.…”

Section: Methodsmentioning

confidence: 99%

“…The thin rGO film shows low gas permeability when exposed to air, and it has been used to protect other environmentally sensitive materials such as Ag nanowires and perovskites. − Because the rGO is a derivative of 2D graphene oxide (GO), initial interactions of the material with GO can facilitate intimate interfacial bonding with the T x groups of Ti 3 CNT x MXene. Recently, the possibility of obtaining rGO from graphene oxide (GO) at a low temperature (150 °C) with l -ascorbic acid as a reducing agent has been demonstrated . In addition, it can protect MXene from oxidation during processing .…”

Section: Introductionmentioning

confidence: 99%

“…Recently, the possibility of obtaining rGO from graphene oxide (GO) at a low temperature (150 °C) with l -ascorbic acid as a reducing agent has been demonstrated. 35 In addition, it can protect MXene from oxidation during processing. 13 Therefore, the reduction of GO to rGO with l -ascorbic acid could be applied as the next step, strengthening the connection between rGO and MXene.…”

Section: Introductionmentioning

confidence: 99%

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Ambient Processed rGO/Ti₃CNT_x MXene Thin Film with High Oxidation Stability, Photosensitivity, and Self-Cleaning Potential

Purbayanto,

Bury,

Chandel

et al. 2023

ACS Appl. Mater. Interfaces

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Solution-based processing offers advantages for producing thin films due to scalability, low cost, simplicity, and benignity to the environment. Here, we develop conductive and photoactivated self-cleaning reduced graphene oxide (rGO)/Ti3CNT x MXene thin films via spin coating under ambient conditions. The addition of a thin rGO layer on top of Ti3CNT x resulted in up to 45-fold improvement in the environmental stability of the film compared to the bare Ti3CNT x film. The optimized rGO/Ti3CNT x thin film exhibits an optical transmittance of 74% in the visible region of the spectrum and a sheet resistance of 19 kΩ/sq. The rGO/Ti3CNT x films show high rhodamine B discoloration activity upon light irradiation. Under UV irradiation, the electrically conductive MXene in combination with in situ formed semiconducting titanium oxide induces photogenerated charge carriers, which could potentially be used in photocatalysis. On the other hand, due to film transparency, white light irradiation can bleach the adsorbed dye via photolysis. This study opens the door for using MXene thin films as multifunctional coatings with conductive and potentially self-cleaning properties.

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Ambient Processed rGO/Ti₃CNT_x MXene Thin Film with High Oxidation Stability, Photosensitivity, and Self-Cleaning Potential

Purbayanto,

Bury,

Chandel

et al. 2023

ACS Appl. Mater. Interfaces

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“…In this field, the use of hydrazine as a reducing agent has been mainly addressed; however, its toxic nature has led to the pursuit of alternative replacing substances. The use of ascorbic acid (AA) as a green reducing agent of GO has been demonstrated to be a valuable option to get rid of hazardous substances, which allowed obtaining rGO materials with resistivity values and reduction degrees comparable to those produced by hydrazine. − …”

Section: Introductionmentioning

confidence: 99%

Noble-Metal-Free Reduced Graphene Oxide Platforms for Room-Temperature H₂ Sensing in High-Humidity Conditions

Schipani

Puig

Morales

et al. 2023

ACS Appl. Electron. Mater.

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Reduced graphene oxide (rGO) sensorsfree from noble-metal nanoparticleswere prepared and tested at room temperature (21 °C) against hydrogen (H2) in high-humidity conditions (above 90% r.h.). The rGO material was obtained through a simple chemical/thermal protocol from graphene oxide (GO) as the starting material, using ascorbic acid as the reducing agent. The degree of reduction of GO was tuned by modifying the chemo-thermal conditions, which allowed shaping the sensing response. The latter was demonstrated to scale with the sp2 carbon (Csp2) content of the rGO structure, which varied from ∼40%-Csp2 for the least-reduced sample to ∼70%-Csp2 for the highest-reduced material. Current–voltage measurements revealed the influence of the reduction on the electronic conduction mechanisms, evidencing a shift from a strong nonlinear behavior (with a component characteristic of a space charge limited conduction mechanism, SCLC) to a pure ohmic-like response as the reduction of GO proceeded. To evaluate the selectivity of the sensors to the target molecule, different oxidizing and reducing gases other than H2 (CO, CO2, and NO2) were also tested. The highest-reduced sample showed a superior response when exposed to a range of H2 concentrations in an atmosphere with humidity levels above 90% r.h. In these conditions, a negligible cross-sensitivity to CO, CO2, and NO2 was achieved. For the top-performance sensor, the response (t 66) and recovery (t rec) times were calculated to be 72 and 374 s (at 0.05% H2), respectively, with a sensitivity of 0.7% and an estimated detection limit of 2.5 ppm of H2.

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“…Furthermore, organic solvents such as ethanol [17], isopropanol [9], or acetone and acetonitrile [13] have been shown to slow down degradation of Ti 3 C 2 T x suspensions. Several studies have also demonstrated the improved oxidation resistance and stable conductivity of Ti 3 C 2 T x dispersions in presence of antioxidant and capping agents, such as sodium ascorbate [19] and L-ascorbic acid [19][20][21], tannic acid [19]; sodium phosphate, oxalate, and citrate [22]; and sodium polyphosphates, borates, and silicates [23]. The main effect of antioxidants is to protect Ti on the Ti 3 C 2 T x edges from oxide formation.…”

Section: Introductionmentioning

confidence: 99%

Effect of the deposition process on the stability of Ti₃C₂T _x MXene films for bioelectronics

et al. 2023

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Ti3C2T x MXene is emerging as the enabling material in a broad range of wearable and implantable medical technologies, thanks to its outstanding electrical, electrochemical, and optoelectronic properties, and its compatibility with high-throughput solution-based processing. While the prevalence of Ti3C2T x MXene in biomedical research, and in particular bioelectronics, has steadily increased, the long-term stability and degradation of Ti3C2T x MXene films have not yet been thoroughly investigated, limiting its use for chronic applications. Here, we investigate the stability of Ti3C2T x films and electrodes under environmental conditions that are relevant to medical and bioelectronic technologies: storage in ambient atmosphere (shelf-life), submersion in saline (akin to the in vivo environment), and storage in a desiccator (low-humidity). Furthermore, to evaluate the effect of the MXene deposition method and thickness on the film stability in the different conditions, we compare thin (25 nm), and thick (1.0 µm) films and electrodes fabricated via spray-coating and blade-coating. Our findings indicate that film processing method and thickness play a significant role in determining the long-term performance of Ti3C2T x films and electrodes, with highly aligned, thick films from blade coating remarkably retaining their conductivity, electrochemical impedance, and morphological integrity even after 30 days in saline. Our extensive spectroscopic analysis reveals that the degradation of Ti3C2T x films in high-humidity environments is primarily driven by moisture intercalation, ingress, and film delamination, with evidence of only minimal to moderate oxidation.

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Vitamin C-reduced graphene oxide improves the performance and stability of multimodal neural microelectrodes

Cited by 7 publications

References 125 publications

Ambient Processed rGO/Ti₃CNT_x MXene Thin Film with High Oxidation Stability, Photosensitivity, and Self-Cleaning Potential

Ambient Processed rGO/Ti₃CNT_x MXene Thin Film with High Oxidation Stability, Photosensitivity, and Self-Cleaning Potential

Noble-Metal-Free Reduced Graphene Oxide Platforms for Room-Temperature H₂ Sensing in High-Humidity Conditions

Effect of the deposition process on the stability of Ti₃C₂T _x MXene films for bioelectronics

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Vitamin C-reduced graphene oxide improves the performance and stability of multimodal neural microelectrodes

Cited by 7 publications

References 125 publications

Ambient Processed rGO/Ti3CNTx MXene Thin Film with High Oxidation Stability, Photosensitivity, and Self-Cleaning Potential

Ambient Processed rGO/Ti3CNTx MXene Thin Film with High Oxidation Stability, Photosensitivity, and Self-Cleaning Potential

Noble-Metal-Free Reduced Graphene Oxide Platforms for Room-Temperature H2 Sensing in High-Humidity Conditions

Effect of the deposition process on the stability of Ti3C2T x MXene films for bioelectronics

Contact Info

Product

Resources

About

Ambient Processed rGO/Ti₃CNT_x MXene Thin Film with High Oxidation Stability, Photosensitivity, and Self-Cleaning Potential

Ambient Processed rGO/Ti₃CNT_x MXene Thin Film with High Oxidation Stability, Photosensitivity, and Self-Cleaning Potential

Noble-Metal-Free Reduced Graphene Oxide Platforms for Room-Temperature H₂ Sensing in High-Humidity Conditions

Effect of the deposition process on the stability of Ti₃C₂T _x MXene films for bioelectronics