Vitamin D and its influence in circulating trace minerals among Arab adults with or without adequate vitamin D levels

Al‐Daghri, Nasser; Alfadul, Hend; Kattak, Malak Nawaz Khan; Yakout, Sobhy M.

doi:10.1016/j.jksus.2022.102012

Cited by 2 publications

(3 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Further research is recommended to better understand the mechanisms of such a unique association. Furthermore, the very low serum 25(OH)D in the current study (15.5 ± 7.8 ng/mL) compared to previous studies in Iran (21.75 ± 12.3 ng/mL) [ 25 ] and Pakistan (35.99 ± 8.08 ng/mL) [ 30 ] suggests that further vitamin D deficiency epidemiological studies are needed. Recently, there has been ongoing debate among experts regarding the definition (cut-off point)of vitamin D deficiency [ 31 ].…”

Section: Discussioncontrasting

confidence: 76%

“…The exact mechanism by which vitamin D may influence blood pressure is not well known; however, several possible explanations have been posited by researchers to explain the association between vitamin D and hypertension, such as the key influential role of vitamin D on the metabolism of lipid and trace minerals (calcium, phosphate, and magnesium) [ 11 , 30 , 32 ]. Such lipid profiles and trace minerals have an impact on blood pressure status [ 32 , 33 ].The anti-inflammatory effects of vitamin D may mitigate the development of hypertension [ 34 ].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Association between serum 25-hydroxyvitamin D concentrations and hypertension among adults in North Sudan: a community-based cross-sectional study

Hassan,

Abdelbagi,

Osman

et al. 2023

BMC Cardiovasc Disord

View full text Add to dashboard Cite

Background Globally, hypertension represents a major public health problem. The association between 25-hydroxyvitamin D (25[OH]D) levels and hypertension remains unclear. The current study aimed to investigate the association between serum 25(OH)D levels and hypertension among adults in Sudan. Methods A community-based cross-sectional study was conducted among adults in North Sudan. Sociodemographic and clinical data were collected using a questionnaire and face-to-face interviews. Serum 25(OH)D was measured using an enzyme-linked immunosorbent assay. Multivariate logistic regression and multiple linear regression analyses were performed. Results Of the total of 391 participants, 202 (51.7%) were females. The median (interquartile range [IQR]) of participants’ ages was 45(32–55) years. Of the total, 219(56.0%) had hypertension. The median (IQR) of serum25(OH)D was 13.3(9.9–19.7) ng/mL, and 295 (75.4%) participants had vitamin D deficiency (< 20 ng/mL). In multivariable logistic regression, the adjusted odds ratio (AOR) for age = 1.05, 95% confidence interval (CI)1.03‒1.061, the AOR for being female = 2.02, 95% CI, 1.12‒3.66, and body mass index was AOR = 1.09, 95% CI, 1.05‒1.14, all of which were significantly associated with hypertension. However, serum 25(OH)D levels were not associated with hypertension (AOR = 1.01, 95% CI 0.99‒1.05, P = 0.317). In multiple linear regression, while systolic blood pressure was negatively associated with 25(OH)D (coefficient = − 0.28, P = 0.017), there was no significant association between serum 25(OH)D level and diastolic blood pressure (coefficient = − 0.10, P = 0.272) or mean blood pressure (coefficient =–0.03, P = 0.686). Conclusion The current study revealed a negative association between vitamin D and systolic blood pressure. The mechanism of such an association needs further study.

show abstract

Section: Discussioncontrasting

confidence: 76%

Section: Discussionmentioning

confidence: 99%

Association between serum 25-hydroxyvitamin D concentrations and hypertension among adults in North Sudan: a community-based cross-sectional study

Hassan,

Abdelbagi,

Osman

et al. 2023

BMC Cardiovasc Disord

View full text Add to dashboard Cite

show abstract

“…Вельми значущими є результати дослідження, згідно з якими, інтенсивність абсорбції таких біоелементів, як магній (Mg), фосфор (P), кальцій (Ca), залізо (Fe), цинк (Zn) і мідь (Cu), контролюється циркулюючим вітаміном D -25-гідроксикальциферолом -і його метаболітами [1]. Як відомо, цей вітамін виконує численні біологічні функції, зокрема, стимулює дозрівання імунних клітин [29].…”

Section: оригінальні дослідженняunclassified

A linear regression analysis of the effect of bioelements on acute respiratory infections incidence in preschool children

Voloshin,

Marushko,

Savchenko

2023

MPU

View full text Add to dashboard Cite

Purpose - to identify the bioelements having the most significant impact on the susceptibility of preschool children to frequent episodes of acute respiratory infections (ARI). Materials and methods. A total of 30 children (14 boys and 16 girls) aged 1-6 years, undergoing inpatient treatment on ARI, were involved in the clinical study. Two integral indicators of acute respiratory infections recurrence, i.e. the infection index and the resistance index, were taken into account for each patient. The children were tested by X-ray fluorescence analysis of 17 bioelements in their hair - Zn, Fe, Cu, Se, Mn, Cr, Co, Br, Ni, Rb, Sr, Sn, Pb, Ca, K, S, and Cl. The statistical processing of the obtained digital material was performed with IBM SPSS Statistics 28 licensed software. A linear regression analysis with stepwise involvement of predictors was applied. Results. In preschool children, there is a moderate negative correlation between hair Rb content and the calculated resistance index (ρ=-0.405; p=0.026; 95% CI: (-0.674)-(-0.042)), according to which lower concentrations of this bioelement are associated with more frequent episodes of ARI. Additionally, Rb has a statistically significant pairwise relationship with several other bioelements studied and the ratios between them. Rb was demonstrated to be directly and most closely correlated with K (ρ=0.842; p<0.001; 95% CI: 0.678-0.926). A prognostic model of the resistance index was obtained, using the linear regression analysis of independent factors. The formula of the prognostic model included only one of the factors studied - the ratio of Mn/Cr content in hair. The informativeness of the mentioned model was 24.9%, which is a quite significant value, taking into consideration a broad range of known predictors for recurrent respiratory infections. Conclusions. The findings are complementary to the available scientific data on the participation of the bioelements in providing resistance to frequent ARI in preschool children. It is planned to continue examining the status of particular bioelements in combination with other potential predictors of recurrent respiratory infections. The study was conducted in accordance with the principles of the Declaration of Helsinki. The study protocol was approved by the local ethics committees of the institutions mentioned in the paper. An informed parental consent was obtained for the study in children. No conflict of interests was declared by the authors.

show abstract

Vitamin D and its influence in circulating trace minerals among Arab adults with or without adequate vitamin D levels

Cited by 2 publications

References 27 publications

Association between serum 25-hydroxyvitamin D concentrations and hypertension among adults in North Sudan: a community-based cross-sectional study

Association between serum 25-hydroxyvitamin D concentrations and hypertension among adults in North Sudan: a community-based cross-sectional study

A linear regression analysis of the effect of bioelements on acute respiratory infections incidence in preschool children

Contact Info

Product

Resources

About