2021
DOI: 10.1371/journal.pntd.0009681
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Vitamin d and leishmaniasis: Neither seasonal nor risk factor in canine host but potential adjuvant treatment through cbd103 expression

Abstract: Vitamin D (VitD) deficiency has been shown to be a risk factor for a plethora of disorders. We have shown that dogs with clinical leishmaniasis presented lower VitD serum levels than non-infected dogs, and even lower than those with asymptomatic infection. However, if VitD deficiency is a risk factor to develop clinical leishmaniasis remains to be answered. It is also unknown if VitD participates in Leishmania control. First, we retrospectively analysed VitD concentration in serum samples from 36 healthy dogs … Show more

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Cited by 4 publications
(2 citation statements)
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“…The use of this drug is widespread in European countries [134]. Vitamin D has also been associated with disease progression, and its supplementation has been suggested as a treatment adjuvant, but a study is needed to confirm this hypothesis [135,136].…”
Section: Treatmentmentioning
confidence: 99%
“…The use of this drug is widespread in European countries [134]. Vitamin D has also been associated with disease progression, and its supplementation has been suggested as a treatment adjuvant, but a study is needed to confirm this hypothesis [135,136].…”
Section: Treatmentmentioning
confidence: 99%
“…According to a canine animal model study, vitamin D level is neither seasonal nor risk predictor to transmit leishmaniasis in canines, but the vitamin D levels decrease along with beginning of the active clinical disease, indicating a function in control of parasite. [83] Vitamin D insufficiency was connected to the advancement of leishmaniasis in many ways. Moreover, there has been no link among the status of vitamin D and the cell immune response to Leishmania.…”
Section: Role Of Vitamin Dmentioning
confidence: 99%