Vitamin D and Obesity

Abstract

Objective: The prevalence of overweight and obesity is considered an important public issue in the United States and is increasing among both children and adults. There is evidence of aberrations in the vitamin D-endocrine system in obese subjects. Therefore, we will review the role of vitamin D in the adipose tissue. Methods Conclusion:Vitamin D plays a role in the regulation of adipose tissue. Obese individuals may need higher doses of vitamin D supplementation than do lean individuals to achieve optimal levels of 25OHD 3 .Calcitriol modulates adipokine expression and inhibits anti-inflammatory cytokine expression. Calcitriol definitely has a role in the human adipose tissue because of its active form of vitamin D 3 metabolite, their receptors presented in adipocytes, and itse suppression of PTH levels.

Vitamina D y su relación con factores de riesgo metabólicos para enfermedad cardiovascular en mujeres adultas

“…Por otro lado, algunos estudios han demostrado una asociación positiva entre los niveles de 25 (OH)-D con el C-HDL y una asociación negativa con los triglicéridos 11,12 . En cuanto a la obesidad, existen reportes que señalan una disminución de la 25 (OH)-D en personas obesas tanto adultas como en niños; ello probablemente debido a la captación de vitamina D por el tejido adiposo 13,14 .…”