Vitamin D and seasonal variation among Greek female patients with osteoporosis

Papadakis, Georgios; Keramidas, Ioannis; Kakava, Kassiani; Παππά, Θεοδώρα; Villiotou, Vassiliki; Manitarou, Paraskevi; Kalaitzidou, Styliani; Triantafillou, Eleni; Kaltzidou, Victoria; Pappas, Anastasios

doi:10.1530/endoabs.37.ep235

Cited by 11 publications

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“…Figure 1 showed a fluctuation of 25(OH)D concentrations and mUVI along the blood collection period. The variation of 25(OH)D from December to June was similar to previous studies, which have also found a minimum in March (or late winter/early spring) [ 59 , 60 ] and an increase in spring and summer [ 1 , 48 , 61 ]. Similarly to another Portuguese work, frequency of sufficiency of vitamin D (≥ 75 nmol/L) was below 50% in every month [ 62 ].…”

Section: Discussionsupporting

confidence: 89%

Association between serum 25-hidroxyvitamin D concentrations and ultraviolet index in Portuguese older adults: a cross-sectional study

et al. 2017

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BackgroundThe older population is a risk group for hypovitaminosis D. The Ultraviolet Index (UVI) can be an indicator of potential for cutaneous synthesis of vitamin D but physiological and other environmental factors also influence vitamin D synthesis and status. Knowledge about vitamin D status in Portuguese older adults is limited. This study aims to explore the association between Ultraviolet Index and serum 25-hidroxyvitamin D3 [25(OH)D] levels accounting for other potential influential factors.MethodsA cross-sectional study was conducted between December 2015 and June 2016, in 1497 Portuguese older adults (≥ 65 years) within Nutrition UP 65 project. For each participant, serum 25(OH)D was determined and the mean UVI (mUVI) in the respective residence district was calculated for the previous 30 days. Stepwise linear regression analyses were conducted for the following periods of blood collection: between December and June, December and March and April and June. Standardized regression coefficients (Sβ) and 95% confidence intervals were calculated.ResultsThe median 25(OH)D concentration was 35.9 nmol/L. The UVI was independently and positively associated with 25(OH)D in the models for December–June (Sβ = 0.244, 95% CI: 0.198; 0.291, P < 0.001) and April–June (Sβ = 0.295, 95% CI: 0.299; 0.362, P < 0.001) and independently and negatively associated in December–March period (Sβ = −0.149, 95% CI: -0.211; −0.087, P < 0.001).ConclusionsIn this sample with high vitamin D deficiency frequency, the UVI was a predictor of 25(OH)D levels but the direction of the association varied according to the blood collection period. Our results suggest that accounting for the time of year in future research regarding vitamin status and related public health recommendations may be relevant.Electronic supplementary materialThe online version of this article (10.1186/s12877-017-0644-8) contains supplementary material, which is available to authorized users.

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Section: Discussionsupporting

confidence: 89%

Association between serum 25-hidroxyvitamin D concentrations and ultraviolet index in Portuguese older adults: a cross-sectional study

et al. 2017

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“…Furthermore, according to our study the lower preoperative values of cCa were positively related to PostHypo, while a great percentage of patients had a VitD deficiency, which is common in Greece throughout the year (50). Therefore, we suggest a routine control of Ca metabolism for all patients who are candidates for thyroidectomy.…”

Section: Discussionsupporting

confidence: 50%

Identification of Patients at High Risk for Postsurgical Hypoparathyroidism

Kakava

Tournis

Makris

et al. 2020

In Vivo

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Background/Aim: Postsurgical hypoparathyroidism (PostHypo) is a common complication after total thyroidectomy. We studied the risk factors associated with PostHypo. Patients and Methods: The study included 109 women, (mean age: 50.7±10.75 years), who underwent total thyroidectomy for thyroid diseases. Results: Based on the development of biochemical hypocalcemia on the first postoperative day following total thyroidectomy, (cCa<8.4 mg/dl), 37 women developed PostHypo and 72 did not. Younger age, a lower preoperative corrected calcium and the presence of parathyroid glands in the specimens were related to the development of PostHypo. Of all patients, 51.4% had a vitamin D deficiency. A parathyroid hormone (PTH) value ≤9.4 pg/ml was 84.9% sensitive and 71.4% specific to predict PostHypo on the 1 st postoperative day. A 50% reduction of the PTH value on the 1 st postoperative day from the preoperative level could identify patients who develop PostHypo with 76% sensitivity and 75% specificity. Conclusion: PTH postoperative measurement and its alteration from the preoperative level can be used to identify patients who are at increased risk to develop PostHypo.

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“…In a feed-forward loop mechanism, metabolic improvement can affect the release of OC from the bone [30]. Moreover, the effect of the decrease in skin vitamin D synthesis connected with the fall in ultraviolet B radiation could also play a role (the study was conducted from September to March) [31].…”

Section: Discussionmentioning

confidence: 99%

Bone Mineral Density and Bone Turnover Markers in Postmenopausal Women Subjected to an Aqua Fitness Training Program

Wochna¹,

Nowak²,

Huta-Osiecka³

et al. 2019

IJERPH

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The purpose of this study was to analyze the influence of aqua fitness training in deep water on bone tissue. The study was performed with 18 postmenopausal women separated into two groups: training and control groups. Before and after the training program, the hip and spine areal bone mineral density were measured along with the biochemical parameters of serum concentration of osteocalcin (OC) and C-terminal telopeptide of type I collagen (CTX). The most significant effect was found in differences between the two groups of women in terms of femur strength index (p < 0.05) during the period of the training program. The study demonstrated that an aqua fitness training program caused favorable changes in femur strength index in postmenopausal women, and this kind of exercise could be a useful form of physical activity for postmenopausal women.

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Vitamin D and seasonal variation among Greek female patients with osteoporosis

Cited by 11 publications

References 0 publications

Association between serum 25-hidroxyvitamin D concentrations and ultraviolet index in Portuguese older adults: a cross-sectional study

Association between serum 25-hidroxyvitamin D concentrations and ultraviolet index in Portuguese older adults: a cross-sectional study

Identification of Patients at High Risk for Postsurgical Hypoparathyroidism

Bone Mineral Density and Bone Turnover Markers in Postmenopausal Women Subjected to an Aqua Fitness Training Program

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