Vitamin D deficiency in Egyptian and Yemeni primary knee osteoarthritis patients: Relation to physical function and radiographic severity

Sakr, Basma R.; Al-Ashmory, Nabil M.; Hassan, Samia Z.; Al-Akwa, Ahmed A.; Shaker, Olfat

doi:10.1016/j.ejr.2020.06.005

Cited by 2 publications

(1 citation statement)

References 36 publications

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“…Dietary sources of these nutrients include dairy products, salmon fish, mushrooms, almonds, etc., which are not accessible to most of the underprivileged population. In some instances, calcium deficiency could lead to severe comorbidities like osteoporosis (OP) and osteoarthritis (OA) (Sakr et al, 2020;Saleh et al, 2020). OP is a serious illness developed due to calcium deficiency in bones.…”

Section: Introductionmentioning

confidence: 99%

Fortification of raw rice and rice flour using Cissus quadrangularis L. (veldt grape) stem powder to overcome osteoporosis and its associated skeletal complication through staple diet

et al. 2021

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This study aimed to prepare the fortified rice/flour with Cissus quadrangularis (CQ) stem powder to eliminate nutritional deficiency and improve bone health. Mineral analysis by atomic absorption spectroscopy revealed that the CQ stem has adequate quantities of calcium, magnesium, and a moderate amount of phosphorous to meet the Recommended Dietary Allowance (RDA). Thus, the rice and flour were fortified with freeze-dried CQ stem powder to improve its nutraceutical contents. The fortification was done using standard vacuum impregnation and blending process. Furthermore, the recuperative activity of prepared fortified rice (CQFR) and flour (CQFF) was tested in chemically induced osteoporosis and osteoarthritis animal models. The efficiency of CQ fortified diet against these complications was confirmed by hematology, radiology, and histopathological analysis. The rat groups fed with CQFF/CQFR diet showed significant improvement from calcium deficiency and its allied physiological damage.Thus, this study confirms that the CQ fortified rice would provide recovery from skeletal complications associated with calcium deficiency through fixing both homeostasis and bio-accessibility of the calcium.

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Section: Introductionmentioning

confidence: 99%

Fortification of raw rice and rice flour using Cissus quadrangularis L. (veldt grape) stem powder to overcome osteoporosis and its associated skeletal complication through staple diet

et al. 2021

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Associations between biomarkers and skeletal muscle function in individuals with osteoarthritis: a systematic review and meta-analysis

Smith,

Paul,

Steultjens

et al. 2024

Arthritis Res Ther

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Objectives Skeletal muscle dysfunction is the primary cause of functional limitations in osteoarthritis, associated biomarkers have the potential as targets for early disease identification, diagnosis, and prevention of osteoarthritis disability. This review aimed to identify associations between biomarkers and lower limb skeletal muscle function in individuals with osteoarthritis. Methods A systematic literature review and meta-analysis conducted in PubMed, MEDLINE, CINAHL, EMBASE, Scopus, SPORTDiscus and Web of Science databases from inception to 8th August 2023. Two independent reviewers performed the title, abstract, full-text screening, data extraction and methodological quality assessment. A meta-analysis was undertaken based on the available data. Results Twenty-four studies with 4101 participants with osteoarthritis were included (females: 78%; age range; 49 to 71 years). One study reported muscle-specific biomarkers (n = 3), whilst six studies reported osteoarthritis-specific markers (n = 5). Overall, 93 biomarkers were reported, predominately characterised as inflammatory (n = 35), metabolic (n = 15), and hormones (n = 10). Muscle strength and vitamin D reported a significant association (Hedge’s g: 0.58 (Standard Error (SE): 0.27; P = 0.03), k = 3 studies). Walking speed and high-sensitivity C-reactive protein reported no significant associations (Hedge’s g: -0.02 (SE: 0.05; P = 0.73), k = 3 studies). Conclusion Associations between biomarkers and lower limb skeletal muscle function in individuals with osteoarthritis was limited, the few studies exploring lower limb muscle measures were mainly secondary outcomes. Furthermore, biomarkers were largely related to overall health, with a lack of muscle specific biomarkers. As such, the mechanistic pathways through which these associations occur are less evident, and difficult to draw clear conclusions on these relationships. Trial registration Registered on PROSPERO (CRD42022359405).

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Vitamin D deficiency in Egyptian and Yemeni primary knee osteoarthritis patients: Relation to physical function and radiographic severity

Cited by 2 publications

References 36 publications

Fortification of raw rice and rice flour using Cissus quadrangularis L. (veldt grape) stem powder to overcome osteoporosis and its associated skeletal complication through staple diet

Fortification of raw rice and rice flour using Cissus quadrangularis L. (veldt grape) stem powder to overcome osteoporosis and its associated skeletal complication through staple diet

Associations between biomarkers and skeletal muscle function in individuals with osteoarthritis: a systematic review and meta-analysis

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