Vitamin D Dosing: Basic Principles and a Brief Algorithm (2021 Update)

Bleizgys, Andrius

doi:10.3390/nu13124415

Cited by 38 publications

(20 citation statements)

References 55 publications

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“…The common dose of VD supplementation to raise the serum 25(OH)D by 15-25 nmol/L is 1000 IU; however, recommendations vary across countries in the range of 400 to 2000 IU per day [21]. In the case of VD deficiency or insufficiency, supplementation dose needs to be determined based on the baseline 25(OH)D serum levels and age [41]. Despite the lack of commonly established repletion treatments, both oral and intramuscular cholecalciferol (300,000 IU) effectively increased serum 25(OH)D levels in VD-deficient healthy adults [42].…”

Section: Discussionmentioning

confidence: 99%

Vitamin D Is Associated with Clinical Outcomes in Patients with Primary Biliary Cholangitis

Ebadi

Lytvyak

et al. 2022

Nutrients

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Vitamin D (VD) deficiency has been associated with clinical outcomes in patients with chronic liver disease. This study aims to identify the prevalence of VD deficiency in patients with primary biliary cholangitis (PBC) and its association with treatment response to ursodeoxycholic acid (UDCA), cirrhosis development, and liver-related events (mortality and liver transplantation). Two hundred and fifty-five patients with PBC diagnosis were evaluated. Patients with VD levels below 50 nmol/L were defined as deficient. Treatment response to UDCA was defined according to the Toronto criteria. Independent risk factors were identified using binary logistic and Cox regression analysis. The mean level of serum VD was 77 ± 39 nmol/L, and 64 patients (25%) were VD deficient. Incomplete response to UDCA was more prevalent in VD-deficient patients compared to their counterparts (45% vs. 22%; p < 0.001). The risk of cirrhosis development (hazard ratio (HR) 1.93; 95% confidence interval (CI) 1.17–3.19, p = 0.01) and liver-related mortality or need for liver transplantation (HR 3.33, 95% CI, 1.57–7.07, p = 0.002) was higher in VD-deficient patients after adjusting for confounders. Vitamin D deficiency is frequent in patients with PBC and is associated with incomplete response to UDCA, cirrhosis development, and liver-related mortality or need for liver transplantation.

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Section: Discussionmentioning

confidence: 99%

Vitamin D Is Associated with Clinical Outcomes in Patients with Primary Biliary Cholangitis

Ebadi

Lytvyak

et al. 2022

Nutrients

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“…Concentrations of 25-OH-D between 50 nmol and 75 nmol/L (<30 ng/mL) should be considered as vitamin D insufficiency . Conversely, 25-OH-D concentrations between 75 and 150 nmol/L represent the normal range [ 11 ], whereas 25-OH-D concentrations between 150 and 250 nmol/L should be considered as increased levels, and concentrations greater than 250 nmol/L as overload [ 12 ].…”

Section: Vitamin D Deficiency: Definition and Prevalencementioning

confidence: 99%

Vitamin D Status and Parkinson’s Disease

et al. 2022

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Parkinson’s disease (PD) is a complex and progressive neurodegenerative disease, characterized by resting tremor, rigidity, slowness of movement, and postural instability. Furthermore, PD is associated with a wide spectrum of non-motor symptoms that add to overall disability. In recent years, some investigations, from basic science to clinical applications, have focused on the role of vitamin D in PD, often with controversial findings. Vitamin D has widespread effects on several biological processes in the central nervous system, including neurotransmission in dopaminergic neural circuits. Various studies have recorded lower levels of vitamin D in PD patients than in healthy controls. Low vitamin D status has also been correlated with the risk for PD and motor severity, whereas less is known about the effects vitamin D has on cognitive function and other non-motor symptoms. This review aims to better characterize the correlation between vitamin D and PD, clarify the role of vitamin D in PD prevention and treatment, and discuss avenues for future research in this field.

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“…Low vitamin D levels can be corrected by consuming an oral supplement under medical supervision or by ensuring daily sunlight exposure. Readers may refer to the dosing strategies suggested by Bleizgys (2021) [ 62 ] for vitamin D supplementation.…”

Section: Resultsmentioning

confidence: 99%

Nutrition Recommendations for Table Tennis Players—A Narrative Review

Huang¹,

Ng²,

Lee

2023

Nutrients

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Table tennis (TT) is the second most popular racket sport globally and was the sixth most widely played Olympic sport in 2005. It is an indoor racket sport requiring a mixture of power, agility, alertness and fast reactions. Players need to move quickly around a table to receive the ball and produce powerful returns. New rules such as increased ball size and a change in ball material have changed the ball’s trajectory, increasing the overall duration and intensity of game play. Scientific research on TT is growing but there has been no systematic review of nutrition for the sport. This review provides nutritional recommendations for TT athletes based on the physiological demands of TT, including energy expenditure during training and competitions, and the main metabolic pathways of TT. Guidelines on the daily intakes of carbohydrate, protein and fat are discussed in addition to hydration strategies. Micronutrients of concern for TT athletes include iron, magnesium and vitamin D and their recommended intakes are also provided. The timing and dose of ergogenic aids that may improve TT performance such as caffeine, creatine, lutein and zeaxanthin and beta-alanine are reviewed. Specific nutritional strategies for intakes leading up to competitions, post training and competition recovery and nutritional strategies for travel are also addressed.

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Vitamin D Dosing: Basic Principles and a Brief Algorithm (2021 Update)

Cited by 38 publications

References 55 publications

Vitamin D Is Associated with Clinical Outcomes in Patients with Primary Biliary Cholangitis

Vitamin D Is Associated with Clinical Outcomes in Patients with Primary Biliary Cholangitis

Vitamin D Status and Parkinson’s Disease

Nutrition Recommendations for Table Tennis Players—A Narrative Review

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