Vitamin D levels in a population from Argentina with metabolic disorders

Abstract

Background: Metabolic disorders are a public health problem worldwide. The vitamin D status in patients with metabolic diseases is not a routine procedure. The aim of this study was to determine the prevalence of vitamin D deficiency and examine the correlation between vitamin D status and cardiometabolic parameters in Latin American population with metabolic disorders.Methods: This observational study with a cross-sectional design included 151 patients with metabolic disorders (type 2 diabetes, hypothyroidism, type 2 diabetes with hypothyroidism, and excess weight). A fasting blood sample was collected and analyzed to determine the levels of 25-hydroxyvitamin D, calcium, glucose, hemoglobin A1c, thyroid-stimulating hormone, and free thyroxine. Anthropometric and blood pressure measurements were also performed.Results: According to vitamin D values established by the Institute of Medicine, subjects with metabolic disorders group showed: 23% risk to bone health (9.42 ± 3.04 ng/mL), 45% risk of insufficiency/deficiency (17.05 ± 2.12 ng/mL), and 32% had sufficient levels (26.34 ± 6.74 ng/mL), whereas healthy subjects group showed significantly higher values than metabolic diseases group (37.25 ± 7.72). In addition, vitamin D levels were inversely correlated with elevated body mass index (29.13 ± 5.15 kg/m 2 ), systolic blood pressure (126.50 ± 15.60 mm Hg), fast blood glucose (106.29 ± 33.80 mg/dL), and hemoglobin A1c (6.40% ± 1.38%) values.Conclusion: Subjects with metabolic disorders and with adequate nutritional intake of vitamin DÀrich foods and frequent exposure to sunlight have low serum vitamin D concentrations compared to the general population and vitamin D status should be assessed in these patients.

Chronic kidney disease prevalence in asymptomatic patients with risk factors—usefulness of serum cystatin C: a cross-sectional study

“…BP was averaged from two seated measurements using an automatic monitor (Omron Healthcare Co., HEM-7120, China). 11 …”

“…BP was averaged from two seated measurements using an automatic monitor (Omron Healthcare Co., HEM-7120, China). 11 According to the World Health Organization (WHO), overweight and obesity are defined as BMI values equal to or higher than 25 and 30 kg/m 2 , respectively. 12 Arterial hypertension was defined as BP $130/85 mm Hg and/or current use of antihypertensive drugs (cutoff values established by International Diabetes Federation and the American Heart Association/National Heart, Lung, and Blood Institute).…”