Vitamin D Role in Chronic Dacryocystitis

Abstract

Introduction: Vitamin D deficiency has been associated with dry eye disease or Sjogren's syndrome. Due to the anti-inflammatory role of vitamin D in eye diseases, it has been proposed to study the role of this vitamin in chronic dacryocystitis, which is an infectious and inflammatory process affecting the nasolacrimal system. Objective: Determine the association between vitamin D levels with the presence of chronic dacryocystititis.Materials and Methods: A cross-sectional descriptive observational study analyzed a sample of 40 individuals, of whom had been diagnosed with chronic dacryocystitis. Biochemical tests for serum 25-hydroxyvitamin D (vitamin D) were subjected to the entire sample. The difference in the means was calculated using the T-test for associated data. The reference significance value was 0.05.Results: Chronic dacryocystitis commonly occurs in the age group of 51 to 67 years. Women were more vulnerable to infection than men. No association was found between the presence of chronic dacriocystitis and vitamin D levels (p-0.755). It is recommended to use larger cohorts as well as multicenter studies evaluating this association, such as supplemental use of vitamin D on a large scale.Conclusions: Low vitamin D levels are not associated with the presence of chronic dacriocystitis.