2023
DOI: 10.15789/2220-7619-vds-2033
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Vitamin D signal cascade in macrophages against <i>Mycobacterium tuberculosis</i>

Abstract: Mycobacterium tuberculosis is the causative agent of human tuberculosis; enabling multilayered mechanisms to evade from immune response along with reactivation of the process with subsequent pathogen dissemination. Modification of immune responses through imbalanced intracellular signaling pathways and reprogramming of differential gene expression is one of such mechanisms. Modification targets for M. tuberculosis are the genes which products are involved in lipid metabolism and apoptosis, a key to eliminate i… Show more

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