Vitamin D status and vitamin D deficiency risk factors among pregnancy of Shanghai in China

Yang, Chun; Wu, Jianhua; Ge, Shengfang; Sun, Wenguang

doi:10.1186/s12884-021-03889-0

Cited by 20 publications

(22 citation statements)

References 51 publications

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“…More than two-thirds of the 125 enrolled pregnant women presented with VD deficiency or severe VD deficiency. The high prevalence of VD deficiency and insufficiency among pregnant women in this study is similar to those of studies conducted in Switzerland in 2012–2015, China in 2016, Japanese in 2019, and Napel in 2020 [ 30 , 31 , 32 , 33 ]. Swiss women had a mean serum 25(OH)D level of approximately 37 nmol/L (15 ng/mL) and one-third of the overall study population ( n = 1382) had a serum 25(OH)D level < 25 nmol/L (<10 ng/mL); thus, they were seriously vitamin D deficient [ 30 ].…”

Section: Discussionsupporting

confidence: 87%

Associations between Vitamin D Deficiency and Carbohydrate Intake and Dietary Factors in Taiwanese Pregnant Women

Lin

Lee

et al. 2023

Medicina

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This cross-sectional observation study investigated the vitamin D (VD) status in Taiwanese pregnant women and the effects of VD supplementation and macronutrient intake on serum 25-hydroxy-vitamin D (25[OH]D) level. Data on VD intake, daily sunlight exposure, and carbohydrate intake were obtained from 125 pregnant women at 30–37 weeks’ gestation. Serum 25[OH]D level was measured before delivery in all enrolled women; and the mean 25(OH)D level was 43 nmol/L or 17.2 ng/mL. The 25(OH)D level was significantly correlated with total VD intake of pregnant women (r = 0.239; p = 0.007). The severe VD deficiency group (n = 16; mean of 25(OH)D level = 8.5 ng/mL) had significantly lower total VD intake and supplementation than the groups with VD deficiency (n = 69), insufficiency (n = 32), and sufficiency (n = 8). Those with ≥400 IU/day total VD intake (including VD from food and supplementation) had significantly higher 25(OH)D concentration than those with <400 IU/day total VD intake. Those with 400 IU/day VD supplementation could significantly increase serum 25(OH)D concentrations for pregnant women. Among 85 pregnant women with carbohydrate intake of ≥300 g/day, serum 25(OH)D levels were negatively correlated with carbohydrate intake (p = 0.031). In conclusion, VD deficiency was highly prevalent in Taiwanese pregnant women. VD supplementation was the most effective method for increasing 25(OH)D concentration in pregnant women. Higher carbohydrate intake might reduce 25(OH)D levels.

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Section: Discussionsupporting

confidence: 87%

Associations between Vitamin D Deficiency and Carbohydrate Intake and Dietary Factors in Taiwanese Pregnant Women

Lin

Lee

et al. 2023

Medicina

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“…A high prevalence of vitamin D deficiency up to 62.34% was reported in South China [23] . Recent evidence showed that pregnant women in Shanghai are generally deficient in vitamin D, the result suggest that 72.5% of the participants were vitamin D deficient [24] . At present, the classification standard for the determination of serum 25(OH)D concentration recommended by the IOM is still an indicator commonly used internationally to categorize the vitamin D status in adults.…”

Section: 【【【Discussion】】】mentioning

confidence: 97%

Is low vitamin D status in pregnancy associated with adverse outcomes? ：a prospective cohort study

Shi¹,

Yao²,

Lei³

et al. 2022

Preprint

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Objectives: The relative contributions of vitamin D status to pregnancy complications are not fully understood. We investigated the correlation between vitamin D status and pregnancy outcomes. Design: Prospective analysis of cases Setting: China Population or Sample: A total of 1766 pregnant women admitted to The Eighth Affiliated Hospital, Sun Yat-sen University and Guangdong Women and Children Hospital between January 2019 and December 2020. Methods: This prospective cohort study was performed on women who paid antennal visits during their whole gestation. Serum 25-hydroxyvitamin D [25(OH)D] concentrations were measured among women before 24 weeks of gestation. Associations between maternal vitamin D status, maternal characteristics, and pregnancy outcomes were assessed. The adjusted odds ratio (OR) for adverse pregnancy outcomes was calculated using the logistic regression analysis. Results: Among all the participants ,192(10.87%), 1023(57.93%) and 551(31.20%) were defined as vitamin D sufficiency, insufficiency, and deficiency, respectively. There was no significant difference in vitamin D between pregnant women with adverse pregnancy outcomes and those without adverse pregnancy outcome. Neither vitamin D deficiency nor insufficiency was associated with adverse pregnancy outcomes compared with vitamin D sufficiency. Risks of adverse outcomes were as follows: GDM (OR=0.72 95%CI 0.46-1.14; OR=0.86 95%CI 0.57-1.30), SGA (OR=1.38 95%CI 0.73-2.60; OR=1.28 95%CI 0.70-2.34), early preterm delivery (OR=0.59 95%CI 0.13-2.70; OR=0.84 95%CI 0.23-3.00), PE (OR=3.44 95%CI 0.43-27.52; OR=2.40 95%CI 0.31-18.50), and postpartum hemorrhage (OR=0.58 95%CI 0.33-1.03; OR=0.81 95%CI 0.49-1.35). Conclusions: Low vitamin D status may not be associated with adverse pregnancy outcomes. Vitamin D screening in all pregnant women seems not reasonable.

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“…Several researchers have highlighted the growing prevalence of vitamin D deficiency throughout the human population irrespective of age, gender, and ethnicity (A. Gupta, 2014b;Holick, 2007;Jin, 2021;Mendes et al, 2020;Palacios & Gonzalez, 2014;Prentice, 2008;Sizar et al, 2021;Stoffers et al, 2022;C. Yang et al, 2021).…”

Section: Introductionmentioning

confidence: 99%

“…This oil‐soluble vitamin plays multiple roles in human health and well‐being, which have been discussed in detail elsewhere (Gil et al., 2018; Glade, 2013; Hanel & Carlberg, 2020; Hii & Ferrante, 2016; Holick, 2008; Hossein‐nezhad & Holick, 2013; Lappe, 2011; Nair & Maseeh, 2012; Reichrath et al., 2008; H. Wang et al., 2017; White, 2013; Zmijewski, 2019). Several researchers have highlighted the growing prevalence of vitamin D deficiency throughout the human population irrespective of age, gender, and ethnicity (A. Gupta, 2014b; Holick, 2007; Jin, 2021; Mendes et al., 2020; Palacios & Gonzalez, 2014; Prentice, 2008; Sizar et al., 2021; Stoffers et al., 2022; C. Yang et al., 2021). The indispensable role of vitamin D in bone health, calcium–phosphorus homeostasis, and parathyroid homeostasis is well‐reported in the literature (Holick, 2002).…”

Section: Introductionmentioning

confidence: 99%

Fortification by design: A rational approach to designing vitamin D delivery systems for foods and beverages

Maurya

Shakya

Bashir³

et al. 2022

Comp Rev Food Sci Food Safe

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Over the past few decades, vitamin D deficiency has been recognized as a serious global public health challenge. The World Health Organization has recommended fortification of foods with vitamin D, but this is often challenging because of its low water solubility, poor chemical stability, and low bioavailability. Studies have shown that these challenges can be overcome by encapsulating vitamin D within well‐designed delivery systems containing nanoscale or microscale particles. The characteristics of these particles, such as their composition, size, structure, interfacial properties, and charge, can be controlled to attain desired functionality for specific applications. Recently, there has been great interest in the design, production, and application of vitamin‐D loaded delivery systems. Many of the delivery systems reported in the literature are unsuitable for widespread application due to the complexity and high costs of the processing operations required to fabricate them, or because they are incompatible with food matrices. In this article, the concept of “fortification by design” is introduced, which involves a systematic approach to the design, production, and testing of colloidal delivery systems for the encapsulation and fortification of oil‐soluble vitamins, using vitamin D as a model. Initially, the challenges associated with the incorporation of vitamin D into foods and beverages are reviewed. The fortification by design concept is then described, which involves several steps: (i) selection of appropriate vitamin D form; (ii) selection of appropriate food matrix; (iii) identification of appropriate delivery system; (iv) identification of appropriate production method; (vii) establishment of appropriate testing procedures; and (viii) system optimization.

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Vitamin D status and vitamin D deficiency risk factors among pregnancy of Shanghai in China

Cited by 20 publications

References 51 publications

Associations between Vitamin D Deficiency and Carbohydrate Intake and Dietary Factors in Taiwanese Pregnant Women

Associations between Vitamin D Deficiency and Carbohydrate Intake and Dietary Factors in Taiwanese Pregnant Women

Is low vitamin D status in pregnancy associated with adverse outcomes? ：a prospective cohort study

Fortification by design: A rational approach to designing vitamin D delivery systems for foods and beverages

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