Vitamin D status in adults and children in Transcarpathia, Ukraine in 2019

Shchubelka, Khrystyna

doi:10.1186/s40795-020-00380-5

Cited by 13 publications

(31 citation statements)

References 26 publications

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“…Apart from that, use of sunscreen products and sun avoidant behavior is more common among females than males [ 36 ]. Similar results are found in numerous previous studies [ 36 – 38 ]. However, in some other studies, the results were other way round, i.e.…”

Section: Discussionsupporting

confidence: 93%

Concentration levels of serum 25-Hydroxyvitamin-D and vitamin D deficiency among children and adolescents of India: a descriptive cross-sectional study

Mustafa

Shekhar

2021

BMC Pediatr

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Background Vitamin D is an essential micronutrient for the overall health and well-being of individuals. For strong musculoskeletal and neurological development of human body, vitamin D levels during childhood and adolescence have key importance. This is the first national-level study that analyzes the deficiency and concentration of serum 25-Hydroxyvitamin D [25(OH)D)] among Indian children and adolescents with respect to various demographic and socioeconomic characteristics. Methods Data of Comprehensive National Nutrition Survey (CNNS, 2016–18) was utilized for the present study. Vitamin D levels were assessed based on serum 25-hydroxyvitamin D concentration. Prevalence of vitamin D deficiency has been shown for the three age groups: 0–4 years (n = 12,764), 5–9 years (n = 13,482), 10–19 years (n = 13,065). Vitamin D deficiency was defined as: serum 25(OH)D < 12 ng/mL; and insufficiency as: 12 ng/ml ≤ 25(OH) < 20 ng/ml. 25(OH) D level higher than 20 ng/mL was accepted as adequate. Random slope multilevel logistic regression models were employed to assess the demographic and socioeconomic correlates of vitamin D deficiency. Results Mean serum 25(OH)D concentration level was found to be 19.51 ± 8.76, 17.73 ± 7.91, and 17.07 ± 8.16 ng/ml in age group 0–4 years, 5–9 years and 10–19 years respectively. 49.12% of the children aged 0–4 years were having insufficient level of vitamin D. Prevalence of vitamin D deficiency was comparatively higher among female adolescents (76.16%), adolescents living in rural region (67.48), Sikh individuals (0–4 years: 76.28%; 5–9 years: 90.26%; 10–19 years: 89.56%), and adolescents coming from rich households. North-Indian individuals were having substantially higher odds of vitamin D deficiency in all the three age groups. Conclusion The present study demonstrated that the prevalence of vitamin D deficiency is considerably high among children and adolescents of India. The study highlights high-risk group which require prompt policy interventions.

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Section: Discussionsupporting

confidence: 93%

Concentration levels of serum 25-Hydroxyvitamin-D and vitamin D deficiency among children and adolescents of India: a descriptive cross-sectional study

Mustafa

Shekhar

2021

BMC Pediatr

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“…A total of 24 European countries, satisfying the inclusion/exclusion criteria were selected for the analysis 24-47 ( Table 1 ). Countries excluded due to their limited population and/or lower number of COVID-19 tests were Andorra, Channel Islands, Faeroe Islands, Gibraltar, Iceland, Isle of Man, Liechtenstein Luxembourg, Malta, Monaco, Montenegro, San Marino, and Vatical city.…”

Section: Resultsmentioning

confidence: 99%

“…<20 ng/ml or <50 nmol/l). 25,27,31,34,39-41,43,45-47 The size of study population which was used to retrieve data for the prevalence of Vit D deficiency varied from 280 (Slovenia) 43 to 74.235 subjects (Italy). 37…”

Section: Resultsmentioning

confidence: 99%

“…According to the outcomes of our study, in several of the European countries included in this analysis, more than 50% of the adult population was Vit D deficient, which constitutes a factor that should not be disregarded in the planning of public health preventive measures. 25,27,31,34,39-41,43,45-47 Factors that can influence Vit D concentration include the fluctuations of sunlight exposure among seasons, 48 especially the negligible amount of sunlight during winter and cloud covers during summer could potentially reduce the cutaneous synthesis of Vit D in some less south located countries, 49,50 as well as extend of clothing coverage and sunscreen use. 51,52 Furthermore, dietary sources of Vit D are limited and the obesity epidemic in the Europe, which is also related to poorer dietary choices, can worsen its deficiency.…”

Section: Discussionmentioning

confidence: 99%

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Prevalence of vitamin D is not associated with the COVID-19 epidemic in Europe. A critical update of the existing evidence

Bakaloudi

Chourdakis

2021

Preprint

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Background: COVID-19 has emerged as a global pandemic, affecting nearly 104 million people worldwide as of February 4th 2021. In previous published studies, the association between the mean Vit D status of each country and COVID-19 infection rate, and mortality among the adult population in European countries was examined. The aim of this study was to re-examine the relationship between the Vit D status of each country and COVID-19 infection, recovery, and mortality using updated data and a different methodological approach. Methods: Information only form the last decade on Vit D concentration/deficiency for each country was retrieved through literature search on PubMed database. As of February, 4th 2021, COVID-19 infections and mortalities per one million population as well as total recoveries were extracted from the Worldometer website. The association between vitamin D deficiency and COVID-19 infection, recovery, and mortality were explored using correlation coefficients and scatterplots. Results: The prevalence of vitamin D deficiency among European countries ranged from 6.0 (Finland) to 75.5% (Turkey), with several countries facing more than 50% of vitamin D deficiency among their population. Non-significant correlations were observed between the number of COVID-19 infections (r=0.190; p=0.374), recoveries (rs=0.317, p=0.131), and mortalities (r=0.129; p=0.549) per one million population, with the prevalence of vitamin D deficiency. Conclusions: Prevalence of vitamin D deficiency was not significantly associated with either number of infections, recoveries or mortality rate of COVID-19 among European countries. Thus, it is an important parameter to be considered when implementing preventive measures to face COVID-19.

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“…We searched the literature to find studies that report monthly 25(OH)D concentration. We found 15 studies [ 11 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 ] and extracted average monthly 25(OH)D concentration. We also calculated mean 25(OH)D for each month in the UK Biobank dataset (data not shown).…”

Section: Methodsmentioning

confidence: 99%

Comprehensive Analysis of Seasonal and Geographical Variation in UVB Radiation Relevant for Vitamin D Production in Europe

et al. 2022

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Dermal synthesis, following sun exposure, is the main source of vitamin D. This study characterizes ambient UVB radiation relevant for vitamin D production in Europe. A biological weighing function was applied to data from the Tropospheric Emissions Monitoring Internet Service (TEMIS) for 46 capital cities over an 18-year period (2004–2021) to isolate wavelengths relevant for vitamin D production (D-UVB). Cumulative and weighted D-UVB (CW-D-UVB) were calculated to approximate seasonal vitamin D accumulation and diminution. Monthly 25(OH)D concentration measurements were extracted from published reports. All data were analyzed by location and time. Despite a moderate latitudinal range (35–64° N), we observed large—up to five-fold—regional differences: the highest mean diurnal D-UVB dose of 5.57 kJ/m2 (SD = 3.55 kJ/m2) was observed in Nicosia (Cyprus) and the lowest in Reykjavik (Iceland, 1.16 ± 1.29 kJ/m2). Seasonal differences in diurnal D-UVB dose were even more pronounced, with a median 36-fold difference between annual peak and trough depending on a location (range: 10- to 525-fold). The mean duration of “vitamin D winter” was 126 days but varied widely (4 to 215 days). Monthly CW-D-UVB and 25(OH)D changes were very strongly correlated: the changes in 25(OH)D concentration increased by 12.6 nmol/L for every 100 kJ/m2 increment of CW-D-UVB in population-based studies (r2 = 0.79, p-value = 1.16 × 10−37). Understanding the differences in D-UVB radiation can help understand determinants of vitamin D status and guide region- and season-specific safe and effective sunlight exposure recommendations and vitamin D supplementation guidelines.

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Vitamin D status in adults and children in Transcarpathia, Ukraine in 2019

Cited by 13 publications

References 26 publications

Concentration levels of serum 25-Hydroxyvitamin-D and vitamin D deficiency among children and adolescents of India: a descriptive cross-sectional study

Concentration levels of serum 25-Hydroxyvitamin-D and vitamin D deficiency among children and adolescents of India: a descriptive cross-sectional study

Prevalence of vitamin D is not associated with the COVID-19 epidemic in Europe. A critical update of the existing evidence

Comprehensive Analysis of Seasonal and Geographical Variation in UVB Radiation Relevant for Vitamin D Production in Europe

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