Vitamin E Intake and Serum Levels in the General Population: A Global Perspective

Eggersdorfer, Manfred; Weber, Peter

doi:10.1007/978-3-030-05315-4_13

Cited by 5 publications

(9 citation statements)

References 111 publications

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“…The sample size was calculated using the formula N = [ Z 1-α/2 ] 2 × P (1- P )/ d 2 [ 17 ]. Where N is the sample size, Z 1-α/2 (1.96) is the certainty wanted expressed in the percentage point of normal distribution corresponding to the 2-sided level of significant ( α = 0.05); P (13%) is the global prevalence rate of vitamin E deficiency [ 18 ]; d (3%) is the allowable error. Therefore, N = [(1.96) 2 × 0.13 × (1–0.13)]/(0.03) 2 = 483.…”

Section: Methodsmentioning

confidence: 99%

“…The standard weight status categories associated with BMI ranges for adults are: BMI below 18.5 is associated with ‘underweight’ weight status; BMI 18.5–24.9 is associated with ‘normal’ weight status; BMI 25.0–29.9 is associated with ‘overweight’ weight status; BMI 30.0 and above is associated with ‘obese’ weight status [ 21 ]. The vitamin E status categories for healthy adults are classified as follows [ 18 , 22 ]: vitamin E serum concentrations ≤ 12 μmol/L is considered as functional deficiency; between 13 and 29 µmol/L is considered as suboptimal status; ≥ 30 μmol/L is considered as desirable status. The prevalence rate of vitamin E deficiency according to its status categories defined for healthy adults, and its comparison with other countries have been investigated.…”

Section: Methodsmentioning

confidence: 99%

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The low prevalence rate of vitamin E deficiency in urban adults of Wuhan from central China: findings from a single-center, cross-sectional study

et al. 2023

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Background Vitamin E is an essential nutrient in human body famous for its antioxidant and non-antioxidant functions. However, little is known about vitamin E deficiency status in urban adults of Wuhan from central China. Our aim is to describe the distribution of both circulating and lipid-adjusted serum vitamin E concentration in urban adults of Wuhan. Methods We hypothesized that the prevalence rate of vitamin E deficiency would be low in Wuhan in consideration of the Chinese food composition. A cross-sectional study with 846 adults was performed in a single-center. Concentrations of vitamin E were measured by liquid chromatography coupled with tandem mass spectrometry (LC–MS/MS). Results The median (interquartile range, IQR) of serum vitamin E concentration was 27.40 (22.89–33.20) μmol/L while that of serum vitamin E concentration adjusted by total cholesterol or the sum of cholesterol (TC) and triglyceride (TG) (the sum of cholesterol and triglyceride, TLs) were 6.20 (5.30–7.48) and 4.86 (4.10–5.65) mmol/mol, respectively. No significant difference of the circulating and TC-adjusted vitamin E concentration was found between male and female except for vitamin E/TLs. However, concentrations of vitamin E increased significantly (r = 0.137, P < 0.001) with age, but lipid-adjusted concentrations of vitamin E did not. On analysis of risk factors, the subjects characterized by hypercholesterolemia are more likely to exhibit higher circulating but lower lipid-adjusted vitamin E level due to adequacy of the serum carriers for delivery of vitamin E. Only 0.47% of the population were below 12 μmol/L of vitamin E defined as functional deficiency. Conclusion The prevalence rate of vitamin E deficiency in urban adults of Wuhan is low, which is important and useful to clinicians for clinical decision-making in public health practice.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

The low prevalence rate of vitamin E deficiency in urban adults of Wuhan from central China: findings from a single-center, cross-sectional study

et al. 2023

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“…The current adult Dietary Reference Values (DRVs) for vitamin E in UK is determined >3 mg/d, in German-speaking countries 15 mg/d for adult. The French Food Safety Agency (AFSSA) derived a separate reference value of 20-50 mg/d for adults aged 75 years and over [17].…”

Section: Determination Vitamin E Intake Recommendationsmentioning

confidence: 99%

“…Average blood serum concentrations of 20 μmol/L α-tocopherol can be acheived in normal adults on a balanced diet, which includes nuts, seeds and whole grains. Inversely, only 21% of the total data revised in global review [17] indicated a desirable serum concentration of α-tocopherol equal to or above 30 μmol/L. Furthermore, 66% of all subentries ranged between 12 and 30 μmol/L.…”

Section: Vitamin E Status In the Populationmentioning

confidence: 99%

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Vitamin E: Recommended Intake

Schwarzová¹,

Fatrcová-Šramková²,

Tvrdá³

et al. 2021

Biochemistry

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Data of vitamin E intake and status are controversial. Vitamin E is an essential micronutrient for humans and achieving an optimal status is assumed to produce beneficial health outcomes. Dietary intake recommendations for vitamin E vary considerably by different countries and organizations. It appears to be still a challenge to define these despite the wealth of data published. Vitamin E requirements have been proposed to depend on other nutritional factors, such as the intake of polyunsaturated fatty acids (PUFA). Although several foods contain naturally occurring sources of vitamin E, it is frequently the case that the intake recommendations are not achieved. Several other dietary factors affect the need for vitamin E. In this regard, significant challenges to be considered include the efficiency of other tocopherol variants and their properties that could affect the revision of the nutritional recommendations for vitamin E. Particularly, an ever-increasing evidence indicates that other vitamin E homologs may potentially present with a higher biological activity. Low dietary consumption of vitamin E, coupled with compelling evidence that increased intake of vitamin E above current recommendations for the general population may benefit older individuals.

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Global human-edible nutrient supplies, their sources, and correlations with agricultural environmental impact

White

Gleason

2022

Sci Rep

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Food production, sustainable development, population growth, and agricultural environmental impacts are linked global problems that require complex solutions. Many efforts evaluating these challenges primarily evaluate dietary strategies designed for health and environmental objectives without considering the subsequent adaptations required by the global food supply. Here we use a complementary approach to summarize trends and variability in the current agricultural system in the context of the growing population and impending environmental challenges. Globally, agricultural systems produce sufficient nutrients to feed 10 billion people with the exception of Ca, DHA + EPA, vitamins B4, D, and E. In a network analysis, greenhouse gas emissions were conditionally dependent on ruminant meat and milk, while water use was conditionally dependent on vegetable and fruit production; however, supplies of most nutrients were also dependent on these same production categories, suggesting trade-offs between nutritional and environmental objectives. Future work should evaluate strategies to address these compromises (i.e., improving water use efficiency and reducing greenhouse gas emissions), to explore to what extent such compromises are biophysically essential or merely a product of the current agricultural system structures. Given the time-sensitive nature of population growth and environmental concerns, strategies to make more effective use of currently produced agricultural products will also be critical complementary strategies to sustainably feed the growing population which can work in concert with other agricultural-, diet- and policy-focused efforts.

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Vitamin E Intake and Serum Levels in the General Population: A Global Perspective

Cited by 5 publications

References 111 publications

The low prevalence rate of vitamin E deficiency in urban adults of Wuhan from central China: findings from a single-center, cross-sectional study

The low prevalence rate of vitamin E deficiency in urban adults of Wuhan from central China: findings from a single-center, cross-sectional study

Vitamin E: Recommended Intake

Global human-edible nutrient supplies, their sources, and correlations with agricultural environmental impact

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