Vitamin K deficiency and covid-19

Anastasi, Emanuela; Ialongo, Cristiano; Labriola, R.; Ferraguti, Giampiero; Lucarelli, Marco; Angeloni, Antonio

doi:10.1080/00365513.2020.1805122

Cited by 46 publications

(34 citation statements)

References 8 publications

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“…IL-6 is a multifunctional cytokine that is promptly and transiently produced by T cell and macrophage in response to infections and tissue injuries, with a key role in host defense through the stimulation of acute phase responses, hematopoiesis, and immune reactions [9]. Several findings underline the pivotal role of IL-6 also in the differentiation of B-cells into antibody producing plasma cells and immunoglobulin secretion [10,11,12]. Aberrant levels of IL-6 have been demonstrated also in several autoimmune disease, in obesity as well as in Multiple Myeloma (MM) [13,14,15].…”

Section: Introductionmentioning

confidence: 99%

Transient plasma cell dyscrasia in COVID-19 patients linked to IL-6 triggering

Farina

Labriola

Ialongo

et al. 2021

Microbes and Infection

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This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

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Section: Introductionmentioning

confidence: 99%

Transient plasma cell dyscrasia in COVID-19 patients linked to IL-6 triggering

Farina

Labriola

Ialongo

et al. 2021

Microbes and Infection

Self Cite

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“…Actually, it has been reported that vitamin K deficiency is strongly associated with admission to ICU [233]. In addition, the low levels of vitamin K seem to contribute to increasing levels of IL-6 release and Th2 storm activation [234].…”

Section: Vitamin Kmentioning

confidence: 99%

Nutraceuticals in the Prevention of Viral Infections, including COVID-19, among the Pediatric Population: A Review of the Literature

Parisi

Carota

Castracani

et al. 2021

IJMS

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In recent years, there has been a growth in scientific interest in nutraceuticals, which are those nutrients in foods that have beneficial effects on health. Nutraceuticals can be extracted, used for food supplements, or added to foods. There has long been interest in the antiviral properties of nutraceuticals, which are especially topical in the context of the ongoing COVID-19 pandemic. Therefore, the purpose of this review is to evaluate the main nutraceuticals to which antiviral roles have been attributed (either by direct action on viruses or by modulating the immune system), with a focus on the pediatric population. Furthermore, the possible applications of these substances against SARS-CoV-2 will be considered.

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“…Low vitamin K, which is mainly known as an effector of blood clotting, has also been shown to be associated with the COVID-19 infection (Anastasi et al, 2020). Some patients who have died or have been hospitalized as a result of the novel coronavirus have reportedly been found to be deficient in vitamin K (see: https://www.foxnews.com/ health/vitamin-k-coronavirus-pandemic-should-you-takeit; and https://www.theguardian.com/science/2020/jun/05/ vitamin-k-could-help-fight-coronavirus-study-suggests).…”

Section: Vitamin Kmentioning

confidence: 99%

Coronavirus management and control: Nutrition and alternative medicines

Guha

Chakraborty

2021

Nutr Health

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Background: In late December 2019, the outbreak of COVID-19 caused by the coronavirus severe acute respiratory syndrome-CoV-2, originated in Wuhan Province, the People’s Republic of China (PRC). The rapid and highly infectious virus quickly spread around the country and has become a global pandemic. Thousands of people have been infected, and have died. Scientists around the world are working on the vaccine; however, an effective cure is yet to be developed. Aims: Search to be made on some alternative antiviral components from the rich sources of traditional herbal medicine in India as well as in the PRC. Here we discuss them with references. Methods: The knowledge gained from the literature search of antiviral known herbal products or Ayurvedic medicines that used to be applied against any viral or bacterial infections in the past, may be considered for deployment against COVID-19, and may be rewarded. Results: Many medicinal compounds are extracted from plants and have led to drug discovery. Similarly, plant products and their analogues have been employed as an early line of defense against COVID-19. Conclusion: Research into ethnobotany, phytochemistry, plant physiology and ecology may be important in protecting the global population from current and future pandemics.

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Vitamin K deficiency and covid-19

Cited by 46 publications

References 8 publications

Transient plasma cell dyscrasia in COVID-19 patients linked to IL-6 triggering

Transient plasma cell dyscrasia in COVID-19 patients linked to IL-6 triggering

Nutraceuticals in the Prevention of Viral Infections, including COVID-19, among the Pediatric Population: A Review of the Literature

Coronavirus management and control: Nutrition and alternative medicines

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