Vitamin K1 Prophylaxis in the Newborn

Vietti, Teresa J.; Stephens, John Craig; Bennett, Kenneth R.

doi:10.1001/jama.1961.03040220039007

JAMA

1961

DOI: 10.1001/jama.1961.03040220039007

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Vitamin K1 Prophylaxis in the Newborn

Teresa J. Vietti¹,

John Craig Stephens²,

Kenneth R. Bennett³

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Cited by 11 publications

References 6 publications

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Role of Feeding and Vitamin K in Hypoprothrombinemia of the Newborn

Keenan¹,

Jewett²,

Glueck³

1971

Arch Pediatr Adolesc Med

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Whole blood prothrombin times were determined serially in five groups of randomly selected well newborn "term" infants, none of whom had clinical evidence of bleeding. Prothrombin values in infants given menadione sodium bisulfite (vitamin K) parenterally shortly after birth were stable. The remainder of the infants who were not given vitamin K were divided into subgroups. Twenty-four hours after the first feeding, prothrombin activity of infants fed cow's milk did not differ significantly from that of infants given vitamin K at birth. In contrast, prothrombin times 24 hours after the first feeding of breast fed infants, of infants given bottled human milk, or of infants receiving only sterile water, were all significantly longer than that of infants given vitamin K parenterally. The responses of these newly born infants to the various feeding regimens appear to represent an in vivo assay for dietary vitamin K. The data document hypoprothrombinemia in the majority of infants who do not receive vitamin K parenterally and emphasize the importance of the administration of a small prophylactic dose of the vitamin to all newly born infants.

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Role of Feeding and Vitamin K in Hypoprothrombinemia of the Newborn

Keenan¹,

Jewett²,

Glueck³

1971

Arch Pediatr Adolesc Med

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show abstract

Abdominal delivery

Adcock¹

1962

American Journal of Obstetrics and Gynecology

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Parental Refusal for Treatments, Procedures, and Vaccines in the Newborn Nursery

Burton

Saini

Maldonado

et al. 2018

Advances in Pediatrics

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Vitamin K1 Prophylaxis in the Newborn

Cited by 11 publications

References 6 publications

Role of Feeding and Vitamin K in Hypoprothrombinemia of the Newborn

Role of Feeding and Vitamin K in Hypoprothrombinemia of the Newborn

Abdominal delivery

Parental Refusal for Treatments, Procedures, and Vaccines in the Newborn Nursery

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