Vitamin D deficiency is associated with diagnosis and severity of childhood atopic dermatitis

Abstract

Vitamin D deficiency and insufficiency are prevalent in Hong Kong Chinese children. Vitamin D deficiency is associated with childhood AD and high total IgE. Serum 25(OH)D levels correlate inversely with both long- and short-term AD severity.

Estimation of Calcidiol Level in Serum of Atopic Dermatitis Patients before and after NB-UVB Phototherapy in Comparison to Oral Vitamin D Therapy

“…The consistency of such a finding in a large number of studies [5][6][7][17][18][19][20][21][22], confirms that the low level of calcidiol in such a disease is not a coincidence, and that calcidiol deficiency has a possible role in the pathogenesis of AD. The controversy in the serum level of calcidiol in AD patients is mainly viewed among adult AD patients, where several studies showed the non-significant alteration of calcidiol levels among patient and control groups [8,9].…”

Missing key factors in nutritional assessment and bone density in children with eczema

“…Vitamin D deficiency, which was prevalent in local children, 6 was a significant covariate for this finding.…”

Assessment of dietary food and nutrient intake and bone density in children with eczema

“…These results echoed those of our recent study in which low serum vitamin D level was highly prevalent in both Hong Kong children with eczema and non-allergic controls. 24 Vitamin D deficiency was associated with disease severity in our eczema children. Our study found eczema severity to be associated with several single-nucleotide polymorphisms of vitamin D pathway genes.…”