Vitamin Status in Patients with Chronic Renal Failure

Stein, Günter; Schöne, S.; Sperschneider, H; Richter, Rolf; Fünfstück, R; Günther, K

doi:10.1159/000415745

Cited by 8 publications

(3 citation statements)

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“…Cyanocobalamine (B12) and folic acid levels are normal in CRF, and supplements are not required (126). Ascorbic acid is often low in CRF patients in conservative or dialytic treatment (127) and a supplement of 30-50 mg has been suggested in uraemic patients. (131), especially in the case of calcium carbonate supplementation.…”

Section: Vitaminsmentioning

confidence: 99%

Expert Working Group report on nutrition in adult patients with renal insufficiency (part 1 of 2)

Toigo¹,

Aparicio²,

Attman³

et al. 2000

Clinical Nutrition

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Section: Vitaminsmentioning

confidence: 99%

Expert Working Group report on nutrition in adult patients with renal insufficiency (part 1 of 2)

Toigo¹,

Aparicio²,

Attman³

et al. 2000

Clinical Nutrition

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“…As the cancer-preventive effect of a diet rich in fruits and vegetables has been clearly and consistently demonstrated by many epidemiological studies, the low consumption of these dietary components in MHD patients may also be a factor for their increased cancer risk [39][40][41][42].…”

Section: Impaired Antioxidant Defense and Increased Formation Of Reacmentioning

confidence: 99%

Cancer in End-Stage Renal Disease: Potential Factors Involved

Vamvakas

Bahner²,

Heidland³

1998

Am J Nephrol

166

113

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Increased incidence of cancer at various sites is observed in patients with end-stage renal disease (ESRD). In particular, lymphomas and carcinomas of the kidney, prostate, liver and uterus show an enhanced prevalence in these subjects compared with the general population. A multitude of factors directly or indirectly associated with the renal disease and the treatment regimens may contribute to the increased tumor formation in these patients. Impaired function of the immune system and of DNA repair mechanisms as well as reduced antioxidant defense, accumulation of carcinogenic compounds partly due to reduced renal elimination as well as chronic infections and inflammations are found more frequently in patients with ESRD compared with the general population and may act in concert to accelerate malignant transformation and tumor formation.

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“…27 There is a desperate need for further research and recommendations to resolve this controversy of vitamin C supplementation in ESRD patients. 28 It needs to be determined, whether ascorbic acid levels should be regularly monitored in dialysis patients. Also, which patients should receive vitamin supplementation and at what doses.…”

Section: Discussionmentioning

confidence: 99%

Scurvy in a hemodialysis patient. Rare or ignored?

Panchal

Schneider

Malhotra

2018

Hemodialysis International

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Chronic kidney disease and dialysis brings with it a plethora of complications, including malnutrition. Strict dietary restrictions in hemodialysis (HD) patients further complicate the picture as it increases the risk of deficiency of micronutrients, specifically water‐soluble vitamins. Today, there is a lack of concrete guidelines concerning recommendations on vitamin supplementation in HD patients. This lack of data is partly due to our incomplete understanding of handling of vitamins in a uremic state. There is a dire need for more data on the impact of dialysis and uremic state on water‐soluble vitamins to facilitate appropriate preventative supplementation. We present a case of scurvy in a HD patient that will contribute toward the understanding of vitamin status in HD. We hope it will aid in screening HD patients for vitamin C deficiency and individualizing supplementation of vitamin C.

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Vitamin Status in Patients with Chronic Renal Failure

Cited by 8 publications

References 0 publications

Expert Working Group report on nutrition in adult patients with renal insufficiency (part 1 of 2)

Expert Working Group report on nutrition in adult patients with renal insufficiency (part 1 of 2)

Cancer in End-Stage Renal Disease: Potential Factors Involved

Scurvy in a hemodialysis patient. Rare or ignored?

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