Vitamins and tuberculosis

Abstract

The importance of vitamins to the development, progression and treatment of tuberculosis is indisputable due to the presence of hypovitaminosis in people with malnutrition or the increase of vitamin deficiency in the setting of the disease. It was established that vitamin preparations exhibit antimicrobial activity, potentiate efficacy and reduce the toxicity of antituberculous drugs. Recent studies have proved the role of vitamins in the metabolism and multiplication of mycobacteria, suggesting the possibility of developing antitubercular compounds based on vitamin preparations with new mechanisms of action. These data are important for the possibility of combating resistance and multidrug resistance in Mycobacterium tuberculosis.