2023
DOI: 10.21203/rs.3.rs-2558916/v1
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Vitexin isolated from Acanthus ilicifolius L. leaf enhances GLUT-4 translocation in experimental diabetic rats

Abstract: Acanthus ilicifolius L. leaf is extensively used in the Indian and Chinese medicine systems to treat diabetes mellitus. In this study, the antidiabetic effect of vitexin isolated from A.ilicifolius leaf extract and their effect on GLUT-4 translocation and PPAR-γ expression was evaluated high-fat diet-streptozotocinocin (HFD-STZ) induced rats. In vitro antidiabetic effect of vitexin was investigated through glucose uptake activity in L6 (rat skeletal muscle) cell lines. Vitexin (10 and 20 mg/kg BW was administe… Show more

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