Vitiligo Treatment with Monochromatic Excimer Light and Tacrolimus: Results of an Open Randomized Controlled Study

Nisticò, Steven Paul; Chiricozzi, Andrea; Saraceno, Rosita; Schipani, Caterina; Chimenti, Sergio

doi:10.1089/pho.2011.3029

Cited by 64 publications

(91 citation statements)

References 18 publications

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“…Therefore, according to the clinical and histological findings present in our patient and to the findings reported in the literature and similarly to other cases (22)(23)(24)(25)(26)(27), we classified our case as a form of neurocutaneous melanosis in an adult patient and we present it for the rarity of this syndrome, for the difficulty of diagnosis, for the potential aggressive behaviour of intracranial lesions that implies a constant attentive follow-up and for the unusual feature of new developing skin lesion during the course of the disease.…”

Section: Discussionsupporting

confidence: 92%

Neurocutaneous Melanosis in a Woman with Multiple Brain Melanocytomas, Cutaneous Melanocytosis and Oral Involvement

et al. 2013

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A 34-year-old female was referred to us for a consultation of her dermatological lesions (pigmented lesions present in her oral cavity and on her right shoulder) in May 2007. These lesions had been present since childhood. Recently, the patient had developed seizures and a headache. An MRI of the brain showed the presence of two intracranial masses. The intracranial tumours were surgically removed whereas skin and mucosal lesions were biopsied. Histological findings of brain tumours were consistent with a diagnosis of "melanocytoma" while cutaneous lesions presented "benign dermal melanocytic infiltrations". Whole brain irradiation was performed. After 3 months a new melanocytic skin lesion appeared on the scalp with histological picture similar to the other cutaneous ones. At the 5-year follow-up examination no recurrence of intracranial tumour or other skin or mucosal lesions were registered. According to the clinical and histological findings, we classify our case as a form of neurocutaneous melanosis in a young adult patient and we present it for the rarity of this syndrome, for the difficulty of the diagnosis, for the potential aggressive behaviour of intracranial lesions that necessitates a constant attentive follow-up and for the unusual feature of new developing skin lesion during the course of the disease.

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Section: Discussionsupporting

confidence: 92%

Neurocutaneous Melanosis in a Woman with Multiple Brain Melanocytomas, Cutaneous Melanocytosis and Oral Involvement

et al. 2013

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“…Only interdisciplinary integrated approaches, knowledge of mechanisms underlying cutaneous diseases and mechanisms of new therapies, including primary prophylaxis with medical sunscreens, secondary prophylaxis with field management of AK, dermatological follow-up screening -individually adapted to known risk factors -and an individually tailored immunosuppressive therapy protocol will be able to manage the patient's skin cancer burden. Guidelines for the follow-up of these patients have recently been published (21)(22)(23)(24)(25)(26)(27)(28).…”

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confidence: 99%

Management of Non-Melanoma Skin Cancer in Solid Organ Transplant Recipients

Specchio

Saraceno

Chimenti

et al. 2014

Int J Immunopathol Pharmacol

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Non-melanoma skin cancer (NMSC) is the most frequent cancer observed in solid organ transplant recipients (SOTR). Early diagnosis, patient education, and modification of immunosuppression are effective measures for reduction of NMSC incidence. Many risk factors have been identified, including age at transplantation, fair skin, type of immunosuppressive drugs, cumulative sun exposure, viral infections, and various genetic markers. Skin self-examination and photoprotection should be encouraged in all transplanted patients. Long-term skin surveillance, early diagnosis and aggressive treatment of any suspicious lesion, reduction of immunosuppressive therapy, and conversion to mammalian target-of-rapamycin (m-TOR) inhibitors can be also effective measures for reduction of NMSC incidence.

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“…Furthermore, we believe that it would be useful to use a specific scale, that we named OPASI (Oral Psoriasis Area and Severity Index), to determine the oral lesion severity and to monitor their clinical trend. On this basis, we believe that more studies with a large number of patients will be needed to reach a significant statistical data on the association of the two conditions (36)(37)(38)(39)(40).…”

Section: Discussionmentioning

confidence: 99%

Clinical Aspects of the Oral Cavity in Patients with Psoriasis: An Initial Study and a Proposal of a New Evaluation Method

et al. 2013

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The involvement of the oral cavity is rare but possible in patients with psoriasis. Most frequently different clinical entities are reported such as geographic tongue, fissures, angular cheilitis and ectopic geographic tongue. This interdisciplinary study was conducted by dermatologists in collaboration with dental hygienists on 22 patients with psoriasis. We examined 11 men and 11 women aged between 25 and 72 years during a period of 6 months. The involvement of the oral cavity was examined and a full photographic evaluation was carried out. A new assessment evaluation named Oral Psoriasis Area and Severity Index (OPASI) is proposed herein. The results obtained show the presence of oral lesions in 45.6% of the cases. This high involvement could be explained by the interdisciplinary nature of the study. We believe OPASI can be useful to assess the severity of lesions of the oral cavity, and may help to evaluate the response to therapy in relation to the Psoriasis Area and Severity Index (PASI) improvement.

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Vitiligo Treatment with Monochromatic Excimer Light and Tacrolimus: Results of an Open Randomized Controlled Study

Cited by 64 publications

References 18 publications

Neurocutaneous Melanosis in a Woman with Multiple Brain Melanocytomas, Cutaneous Melanocytosis and Oral Involvement

Neurocutaneous Melanosis in a Woman with Multiple Brain Melanocytomas, Cutaneous Melanocytosis and Oral Involvement

Management of Non-Melanoma Skin Cancer in Solid Organ Transplant Recipients

Clinical Aspects of the Oral Cavity in Patients with Psoriasis: An Initial Study and a Proposal of a New Evaluation Method

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