Vitrectomy for the removal of idiopathic epiretinal membrane with or without internal limiting membrane peeling: a meta-analysis

Christodoulou, Eleni; Batsos, Georgios; Galanis, Petros; Kalogeropoulos, Chris; Katsanos, Andreas; Alamanos, Yannis; Stefaniotou, Maria

doi:10.1177/2515841420927133

Cited by 7 publications

(3 citation statements)

References 61 publications

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“…Trotz des offensichtlichen Vorteils einer Reduktion der ERM-Rezidivrate sollte aber insbesondere in Fällen, in denen eine sehr starke Adhäsion der ILM vorliegt, die Entscheidung zu einem forcierten und möglicherweise risikoreichen Peeling immer auch im individuellen Fall abgewogen werden, da eine Schädigung durch die chirurgische Manipulation bei der Mobilisierung eines ILM-Flaps nicht ausgeschlossen werden kann [22,137]. Auch die Frage, ob das zusätzliche Peeling der ILM mit einem höheren Risiko für die Entstehung von Mikroskotomen assoziiert ist, war Gegenstand verschiedener Studien und ist nicht abschließend geklärt [16,21,78].…”

Section: Entfernen Der Membrana Limitans Interna (Ilm-peeling)unclassified

Stellungnahme von BVA, DOG und RG zur Entwicklung, Diagnostik und Behandlung der epiretinalen Gliose

2021

Klin Monbl Augenheilkd

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Section: Entfernen Der Membrana Limitans Interna (Ilm-peeling)unclassified

Stellungnahme von BVA, DOG und RG zur Entwicklung, Diagnostik und Behandlung der epiretinalen Gliose

2021

Klin Monbl Augenheilkd

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“…Proliferative cells migrating along the surface of the ILM cause wrinkling, and consequently, vitrectomy with peeling of the ILM might be an effective procedure to release the macular traction [3]. ILM peeling during ERM surgery can decrease recurrence rates and ensure complete removal of ERM fragments [4,5]. Also, ILM peeling in MH surgery has been demonstrated to improve hole closure rates, especially for large (>400 mm) and chronic MH [6][7][8][9][10].…”

Section: Introductionmentioning

confidence: 99%

Perifoveal Microvascular Changes following Internal Limiting Membrane Peeling Surgery for Epiretinal Membrane and Macular Hole

Kim,

Yoon,

Park

et al. 2023

Ophthalmologica

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Introduction: To evaluate perifoveal microvasculature changes following pars plana vitrectomy with internal limiting membrane (ILM) peeling for epiretinal membrane (ERM) and macular hole (MH). Methods: This retrospective study included 59 eyes from 59 patients. Subjects were divided into two groups: a ERM group (n = 43) and a MH group (n = 16) based on the initial diagnosis. Swept-source optical coherence tomography angiography (SS-OCTA) was performed in the macular area, pre- and postoperatively. Perifoveal microvascular changes were calculated using MATLAB from the 6 × 6 mm SS-OCTA images, excluding the foveal avascular zone. Pre- and postoperative perifoveal vessel density (pfVD) was separately analyzed in six sectors (superior, superiotemporal, inferiotemporal, inferior, inferionasal and superionasal) in the superficial capillary plexus (SCP) and deep capillary plexus (DCP). The baseline characteristics and other clinical factors were compared between the ERM and MH groups. Results: The postoperative best corrected visual acuity significantly improved in both groups (p < 0.05). One year after surgery, the pfVD in the SCP of ERM group significantly decreased in the inferotemporal sector (p = 0.049). The postoperative pfVD in the DCP of the MH group significantly decreased in temporal sectors (p < 0.05, respectively). The postoperative mean pfVD in the SCP in the MH group was significantly lower than that in the ERM group (p = 0.003). The presence of a dissociated optic nerve fiber layer (DONFL) was 75% in the MH group and 22% in the ERM group (p = 0.018). The correlation between the pfVD and DONFL was not statistically significant. Conclusion: Postoperative pfVD reduction in the temporal sector, a corresponding area in which DONFL is present after MH surgery, was significantly observed. After vitreoretinal surgery in MH patients, OCTA may serve as a useful tool for monitoring perifoveal microvascular changes, especially in temporal sectors.

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“…The gold standard of therapy for symptomatic ERM is a pars-plana vitrectomy with membranectomy and peeling of the inner limiting membrane (ILM peeling) [ 12 , 13 ]. However, this usually leads to cataract development in phakic eyes.…”

Section: Introductionmentioning

confidence: 99%

Influence of Preoperative Foveal Layers’ Thickness on Visual Function and Macular Morphology by Phacovitrectomy for Epiretinal Membrane

Zhmurin

Grajewski

Krause

2022

Journal of Ophthalmology

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Background. The aim of this retrospective study with short, differently dispersed follow-up is to record the relationships between the pathologies of the individual foveal layers, measured by spectral domain optical coherence tomography (SD-OCT), and to investigate their influence on pre- and postoperative best-corrected decimal far visual acuity (BCVA) by phacovitrectomy for epiretinal membrane (ERM) in comorbidity with cataract. Patients and Methods. 208 eyes of 173 patients with symptomatic idiopathic ERM and moderate cataract were included. Results. In all OCT morphological stages of ERM, as well as in their combination with macular lamellar hole (MLH) and vitreomacular traction (VMT), a significant difference in the thickness of the individual fovea layers was found. In addition, the entire fovea thickening led to the proportional thickening of the individual fovea layers ( p < 0.001 ). The larger the central foveolar (CFT, R2 = −0.238, p = 0.002 ), maximum foveal (MFT, R2 = −0.267, p = 0.001 ), and ONL thickness (R2 = −0.16, p = 0.044 ) were preoperatively, the worse the initial visual acuity was at all OCT stages of ERM. This was even more significant in the presence of a tractive component in the case of MLH or VMT ( p < 0.001 ). In ERM without a traction component, only ONL thickening led to significant postoperative visual acuity reduction (R2 = −0.163, p = 0.047 ). The foveolar retinal thickening (CFT and MFT) of the pure ERM is directly associated with distortion of the retinal layers (R2 = 0.292, p < 0.001 and R2 = 0.287, p < 0.001 ) as well as with separation of the ERM (R2 = 0.168, p = 0.034 and R2 = 0.187, p = 0.018 ). When ERM was combined with tractive component, CFT, ONL, and INL thickness correlated (positively) with the integrity of ellipsoid zone (R2 = 0.342, p < 0.05 ) and external limiting membrane (R2 = 0.548, p < 0.001 ). Conclusions. ONL thickening in ERM without a tractive component serves as a limited prognostic factor of postoperative visual acuity decrease. The preoperative BCVA in the groups of ERM with traction component showed significant correlation with CFT as well as with the thickness of individual foveal layers. VMT in ERM correlates with the disintegration of the ellipsoid zone.

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Vitrectomy for the removal of idiopathic epiretinal membrane with or without internal limiting membrane peeling: a meta-analysis

Cited by 7 publications

References 61 publications

Stellungnahme von BVA, DOG und RG zur Entwicklung, Diagnostik und Behandlung der epiretinalen Gliose

Stellungnahme von BVA, DOG und RG zur Entwicklung, Diagnostik und Behandlung der epiretinalen Gliose

Perifoveal Microvascular Changes following Internal Limiting Membrane Peeling Surgery for Epiretinal Membrane and Macular Hole

Influence of Preoperative Foveal Layers’ Thickness on Visual Function and Macular Morphology by Phacovitrectomy for Epiretinal Membrane

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