Vitreoretinal aspects of permanent keratoprosthesis

Ultra-Widefield Imaging of Posterior Segment Pathology in the Setting of the Boston Keratoprosthesis

“…The multidisciplinary KPro team may face a variety of posterior segment complications including retroprosthetic membrane, infectious endophthalmitis, and retinal detachment and choroidal detachment. [4][5][6] Vitreoretinal complications may be challenging to diagnose in KPro eyes because of difficulties in visualizing the posterior pole through the small 3.35 mm central diameter stem of the keratoprosthesis. Thus, examination of the peripheral retina with traditional techniques such as indirect ophthalmoscopy with a small pupil setting is often marginal or inadequate to fully characterize posterior segment pathology, especially in the far periphery.…”

Boston keratoprosthesis type 1: outcomes of the first 38 cases performed at Moorfields Eye Hospital

“…All had significant proliferative vitreoretinopathy [13]. Retinal detachments in the context of K-Pros are mostly either tractional or rhegmatogenous in origin and tend to have poorer outcomes [14][15][16]. Often patients do not notice any symptoms until the detachment is extensive and severe, despite close follow-up.…”

Bioengineered Corneas Entering the Clinical Realm

“…All of the different designs, however, tend to come with a high risk of severe complications including glaucoma, retroprosthetic membrane formation, retinal detachment and extrusion, leading to a high risk of failure (Matthyssen et al 2018). Several recent reviews of the performance and advances in keratoprostheses can be found (Klufas et al 2015; Salvador-Culla and Kolovou 2016), including a policy article from the NHS in the UK on when KPros would be used (Specialised Commissioning Team 2018).…”