Vitreoretinal Surgery for Complications of Choroidal Tumor Biopsy

Intraocular biopsy of uveal melanoma Risk assessment and identification of genetic prognostic markers

“…This is in accordance with a large case series of 739 consecutive biopsies which reported only one case of endophthalmitis (Grixti et al. ). It is feasible that the heavy radiation following biopsy of uveal melanoma kills potential exogenous bacteria.…”

“…A large series of 448 consecutive TVRC vitrectomy‐assisted biopsies identified a frequency of retinal detachment surgery in 0.4% of cases (Grixti et al. ). Due to limited follow‐up information including potential cases lost to follow‐up, there is risk of a potential underreporting of complications in this study.…”

Concordant chromosome 3 results in paired choroidal melanoma biopsies and subsequent tumour resection specimens

“…Biopsies were performed either transretinally or transsclerally, depending on the size and location of tumour, treatment methods and surgeons’ preference. Briefly, transretinal biopsies were performed under local anaesthesia with a 25-gauge vitreous cutter using a three-port sutureless vitrectomy kit, as previously described 13 14. Transscleral biopsies were performed either as fine needle aspiration biopsy with a 25-gauge needle attached to a 20 mL syringe by flexible plastic tubing; or as an incisional scleral flap biopsy, where a lamellar scleral flap was created, and tumour samples were obtained with Essen forceps as previously described 15.…”

The Histopathological Finding of the Surgically Extracted Atypical Dome-Shaped Choroidal Osteoma

“…However, we eventually needed two additional operations to maintain her visual function. So, we emphasize that the extraction of the tumor could be one of the considerable options when the conclusive diagnosis is needed, but these kinds of invasive techniques should be carefully performed because of concerns for iatrogenic vision-threatening ocular complications or extraocular seeding of tumor cells following tumor sampling [9, 13–18]. …”