VLDLR gene polymorphism associated with abdominal fat in Gaoyou domestic duck breed

Zhao, Nannan; Lin, Shaochong; Wang, Z. Q.; Zhang, T. J.

doi:10.17221/8132-cjas

Cited by 6 publications

(4 citation statements)

References 18 publications

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“…Gong et al (2014) found significant effects of three polymorphisms within the MSTN gene on body weight of duck in consecutive weeks of age (from 5 to 11 weeks), whereas no effects have been estimated for younger birds. Furthermore, Zhao et al (2015) detected significant associations between the VLDLR gene (for four diplotypes) and body weight at 10 weeks in Gaoyou domestic duck breed. Also, considerable effects of these traits were estimated by Huang et al (2007aHuang et al ( , 2007b.…”

Section: Successful Identification Of Duck Genome Region Determining mentioning

confidence: 85%

Successful Identification of Duck Genome Region Determining Desirable Uniformity of Meat Performance Traits

Dobek

Gornowicz

Moliński

et al. 2017

Rev. Bras. Cienc. Avic.

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The objective of this study was to identify genome regions determining duck meat performance traits with possible small variation. In total, 368 crossbred ducks of F2 generation obtained from two parental lines: Pekin-type ducks of Polish origin (A55) and Pekin-type ducks of French origin (GL-30) were recorded. The following seven traits were analyzed: body weight, breast muscle weight, leg muscle weight, water holding capacity in the breast and leg muscles, and color lightness L* of the breast and leg muscles. All birds (including parental and F1 generations) were genotyped (29 microsatellite markers). Means and coefficients of variation (CV) were calculated for 28 full-sibs (four sires by six dams and one sire by four dams). Number of progeny per fullsib group ranged from 7 to 17. The multivariate cluster analysis using grouping by k-means algorithm was used on transformed data. The multivariate cluster analysis gave two clusters: first group with 10 fullsibs and second one with 18 families. Differences among half-sibs in the CV of the recorded traits were determined. It should be noted that one out of five sire groups showed statistically significant differences from the other ones. Moreover, the CVs in this group were smaller. The analysis of microsatellite markers indicated three alleles from three loci were present only in the "superior" sire group. The obtained results indicate a promising opportunity of effective selection for improving carcass technological quality using molecular markers.

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Section: Successful Identification Of Duck Genome Region Determining mentioning

confidence: 85%

Successful Identification of Duck Genome Region Determining Desirable Uniformity of Meat Performance Traits

Dobek

Gornowicz

Moliński

et al. 2017

Rev. Bras. Cienc. Avic.

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“…Many studies have shown associations of VLDLR gene mutations with adiposity and body weight in humans, as previously mentioned in this paper. In a previous study (Zhao et al, 2015), we identified eight SNPs in the homologous domain of VLDLR EGF precursor and showed that there was a significant association between the VLDLR EGF precursor homologous domain and abdominal fat percentage (AFP) in ducks. Similar results were obtained in the present study by analyzing the polymorphism of signal peptide regions.…”

Section: Discussionmentioning

confidence: 99%

“…Our previous study indicated that the VLDLR gene may be associated with abdominal fat in duck (Zhao et al, 2015). The objectives of the present study were to detect different polymorphic sites and investigate its association with growth and carcass traits of Gaoyou ducks, and to conduct further research on the possibility of using VLDLR gene as molecular genetic markers for growth and main carcass traits (abdominal fat percentage -AFP, eviscerated weight percentage -EWP).…”

Section: Introductionmentioning

confidence: 97%

A Novel Polymorphism of VLDLR Signal Peptide Coding Region and Its Association with Growth and Abdominal Fat Traits of Gaoyou Domestic Ducks

Mingliang

Cong

Xuan

et al. 2017

Rev. Bras. Cienc. Avic.

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The VLDLR gene plays important roles in the growth and adiposity in humans and mice. The purpose of this study was to investigate the relationship between VLDLR gene genetic polymorphisms and growth and abdominal fat traits of the Gaoyou domestic duck. A total of 267 Gaoyou ducks were employed for testing. A 18bp deletion was identified in VLDLR signal peptide coding region. The results of χ 2 test suggested that the genotype frequencies of VLDLR signal peptide coding region were not in Hardy-Weinberg equilibrium. Least squares analysis showed that body weight (BW) of -18bp/-18bp genotype ducks was significantly higher than those of other genotypes from six (BW6) (p<0.05) to ten weeks of age (BW10) (p<0.01). The association analysis was performed taken body weight as covariant for abdominal percentage (AFP). Results showed that there was not interaction between genotype (p>0.05) and body weight for AFP and different genotypes had a significant effect on AFP (p<0.05). The results of Bonferroni t-test revealed that the abdominal fat percentage (AFP) of -18bp/-18bp genotype was significantly lower than those of +18bp/-18bp (p<0.05). Preliminary studies have shown that VLDLR may be a candidate gene for the selection for growth and abdominal fat, and the results of the present study indicate that VLDLR strongly influences carcass abdominal fat content of Gaoyou ducks.

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“…Качка -один з найбільш економічно важливих видів свійської водоплавної птиці, оскільки слугує джерелом для отримання якісного м'яса, яєць та пір'я (Huang et al, 2013;Purwantini et al, 2013;Zhao et al, 2015;Ren et al, 2017). Близько 70% качок розводять у Китаї (Tunca et al, 2015;Zeng et al, 2016), за даними ФАО (2015) ця країна є лідером з вирощування молодняку качок.…”

Section: вступunclassified

Shaoxing breed duck polymorphism by microsatellite loci

Chepiha¹,

Kostenko²,

Doroshenko³

et al. 2018

SMLNUVMBA

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Microsatellite markers are now been widely used for the detection and description of micropopulation processes occurring in the populations of domestic animals for the effects of various factors of breeding pressure. Microsatellite loci distributed throughout eukaryotic genomes, making them the preferred genetic marker for high resolution genetic mapping. In recent years, rapid advances have been made in the development of molecular genetic maps. High-density linkage maps are now available for many farm animals, such as cattle, pigs, and goats. In contrast, mapping studies in avian species are much less advanced except in the chicken. According to FAO about 70% of ducks are bred in China. This country is a leader in growing ducks. The Shaoxing breed is one of the three major duck breeds in China. Ducks of this breed are characterized by high performance. According to the Bureau of Product Quality, the age of maturity (the beginning of egg laying) in these birds occurs at 130-140 days. The characteristics of the Shaoxing breed include the fact that the peak period of laying eggs lasts from eight to ten months. On average, one duck in 500 days gives from 290 to 310 eggs, which is one of the highest rates for egg breeds. That is why the purpose of our study was the microsatellite analysis of two populations of Shaoxing breed with 9 locuses was conducted. The selection of birds for the study were carried out on a duck farms in Zhejiang Generation Biological Science and Technology Co., Ltd. and Zhuji Guowei Poultry Development Co, Ltd., and at the laboratory of the Jjejiang Academy of Sciences Institute. Samples collection and DNA preparation: Venous blood samples were collected from 480 ducks (240 ducks of population I and 240 ducks of population II of the Shaoxing breeds) of both populations into 3 ml tubes containing EDTA as anticoagulant agent. In total of 9 investigated loci in the Shaoxing breed population, only one locus was monomorphic (SMO10). The number of different alleles (Na) for each polymorphic locus ranged from 2 (SMO12) to 13 (APL79, CMO11) in population I and from 2 (APL78, SMO12) to 7 (APL79) in population II. On average, one locus had 5.889 alleles in population I and 3.889 of alleles in the population II. The effective number of alleles (Nе) was 1.735 in population I and 1.599 in population II. The number of alleles and the expected heterozygosity (Hexp) values can provide important information for the discrimination of individuals and breeds. The index of expected heterozygosity in population I was 0.336 and 0.307 in population II. The information index (I) was 0,702 in population I and 0,576 in population II. For each population was found private alleles, in population I 6 alleles and in population II just 4 alleles. The results show high level of polymorphism of the studied populations of ducks. The obtained results can be used in the creation of new lines of ducks.

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VLDLR gene polymorphism associated with abdominal fat in Gaoyou domestic duck breed

Cited by 6 publications

References 18 publications

Successful Identification of Duck Genome Region Determining Desirable Uniformity of Meat Performance Traits

Successful Identification of Duck Genome Region Determining Desirable Uniformity of Meat Performance Traits

A Novel Polymorphism of VLDLR Signal Peptide Coding Region and Its Association with Growth and Abdominal Fat Traits of Gaoyou Domestic Ducks

Shaoxing breed duck polymorphism by microsatellite loci

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