Voices behind the left shoulder: Two patients with right-sided temporal lobe epilepsy

Hug, Andreas; Bartsch, Andreas J.; Gutschalk, Alexander

doi:10.1016/j.jns.2011.03.029

Cited by 11 publications

(10 citation statements)

References 13 publications

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“…Prevalence rates of hallucinatory experiences range from 3.3% in epilepsy generally, to 14% in temporal lobe epilepsy specifically (Torta and Keller, 1999). Phenomenologically, these occurrences mirror those documented in clinical (schizophrenia/psychosis) groups, with hallucinations ranging in complexity from ringing and tonal sensations, right through to more complex phenomena including musical and melody perceptions and AVH of human voices (Hug et al, 2011). Patients with epilepsy also demonstrate similar results on behavioral and neuroimaging analyses when compared to patients with schizophrenia, providing further evidence for AVH existing trans-diagnostically, that is, a symptom independent of diagnostic categorization.…”

Section: Epilepsymentioning

confidence: 71%

“…Apart from AVH in healthy and psychological clinical groups, AVH have also been reported to occur in temporal lobe epilepsy (Brasic and Perry, 1997; Hug et al, 2011; Hauf et al, 2012). As a neurological disorder, epilepsy can create the biological threshold under which hallucinatory symptoms develop due to neurological abnormalities [such as hyperfusion of the primary auditory cortex (Hauf et al, 2012)].…”

Section: Epilepsymentioning

confidence: 99%

“…Evidence supporting this model is seen in studies comparing AVH in psychosis to those experienced in temporal lobe epilepsy. Through such a comparison, it can be seen that auditory phenomena are usually perceptually lateralised to the left side in epilepsy patients, with this relationship not evident in psychotic groups (Clarke et al, 2003; Florindo et al, 2006; Hug et al, 2011). As such, a clinical differentiation between AVH experiences in epilepsy and psychotic groups seems likely.…”

Section: Epilepsymentioning

confidence: 99%

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A comprehensive review of auditory verbal hallucinations: lifetime prevalence, correlates and mechanisms in healthy and clinical individuals

Leede-Smith¹,

Barkus²

2013

Front. Hum. Neurosci.

166

131

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Over the years, the prevalence of auditory verbal hallucinations (AVHs) have been documented across the lifespan in varied contexts, and with a range of potential long-term outcomes. Initially the emphasis focused on whether AVHs conferred risk for psychosis. However, recent research has identified significant differences in the presentation and outcomes of AVH in patients compared to those in non-clinical populations. For this reason, it has been suggested that auditory hallucinations are an entity by themselves and not necessarily indicative of transition along the psychosis continuum. This review will examine the presentation of auditory hallucinations across the life span, as well as in various clinical groups. The stages described include childhood, adolescence, adult non-clinical populations, hypnagogic/hypnopompic experiences, high schizotypal traits, schizophrenia, substance induced AVH, AVH in epilepsy, and AVH in the elderly. In children, need for care depends upon whether the child associates the voice with negative beliefs, appraisals and other symptoms of psychosis. This theme appears to carry right through to healthy voice hearers in adulthood, in which a negative impact of the voice usually only exists if the individual has negative experiences as a result of their voice(s). This includes features of the voices such as the negative content, frequency, and emotional valence as well as anxiety and depression, independently or caused by voices presence. It seems possible that the mechanisms which maintain AVH in non-clinical populations are different from those which are behind AVH presentations in psychotic illness. For example, the existence of maladaptive coping strategies in patient populations is one significant difference between clinical and non-clinical groups which is associated with a need for care. Whether or not these mechanisms start out the same and have differential trajectories is not yet evidenced. Future research needs to focus on the comparison of underlying factors and mechanisms that lead to the onset of AVH in both patient and non-clinical populations.

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Section: Epilepsymentioning

confidence: 71%

Section: Epilepsymentioning

confidence: 99%

Section: Epilepsymentioning

confidence: 99%

See 1 more Smart Citation

A comprehensive review of auditory verbal hallucinations: lifetime prevalence, correlates and mechanisms in healthy and clinical individuals

Leede-Smith¹,

Barkus²

2013

Front. Hum. Neurosci.

166

131

View full text Add to dashboard Cite

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“…Such propagation is illustrated by the evolving phenomenology of epileptic seizures where a hallucination may progress from tinnitus to the perception of noise and then finally to noises that sound like incomprehensible voices. 68 This phenomenological progression matches the shift in representation from tones (primary cortex) to the higher order cortical auditory representation of verbal sounds and voices.…”

Section: Beyond Localized Activity—hallucinations Within Networkmentioning

confidence: 55%

From Tones in Tinnitus to Sensed Social Interaction in Schizophrenia: How Understanding Cortical Organization Can Inform the Study of Hallucinations and Psychosis

ffytche

Wible

2014

Schizophrenia Bulletin

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The content, modality, and perceptual attributes of hallucinations and other psychotic symptoms may be related to neural representation at a single cell and population level in the cerebral cortex. A brief survey of some principles and examples of cortical representation and organization will be presented together with evidence for a correspondence between the neurobiology of brain areas activated at the time of a hallucination and the content of the corresponding hallucinatory and psychotic experiences. Contrasting the hallucinations of schizophrenia with other conditions, we highlight phenomenological aspects of hallucinations that are ignored in clinical practice but carry potentially important information about the brain regions and dysfunctions underlying them. Knowledge of cortical representation and organization are being used to develop animal models of hallucination and to test treatments that are now beginning to translate to the clinical domain.

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“…В этом случае тиннитус является лишь симптомом болезни. Это подтверждается результатами работы [20], где были определены слуховые галлюцинации при височной эпилепсии у пациентов.…”

Section: рисunclassified

The Method to Reveal Pathologic Activity of Human Brain in the Magnetic Encephalography Data

Pankratova¹

2013

Math.Biol.Bioinf.

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Аннотация. Предложена методика нахождения опорных точек для выделения сигнала усреднением на фоне шумов большой амплитуды без использования внешней информации о моментах его возникновения. В качестве признаков сигнала используются собственные функции Карунена-Лоэва. Методика позволяет выделять сигнал из экспериментальных данных как с вызванной, так и спонтанной активностью. Применение методики к данным с патологией тиннитус позволяет разделять категорию этих больных на два класса. ВВЕДЕНИЕВ основе электромагнитной активности живых клеток лежит перемещение ионов через клеточную мембрану. Эти заряженные частицы создают внутриклеточный ток, порождающий электромагнитное поле. Работающий нейрон также является слабым источником тока, диполем, который создает вокруг себя электрическое и магнитное поля. Хаотично ориентированные диполи создают поля, векторы напряженности которых в сумме дают ноль, и не регистрируются ни магнитной, ни электрической энцефалографией. Если диполи одинаково ориентированы, их поля суммируются и создают поле, которое может быть измерено приборами, работа которых основана на эффекте Джозефсона -явлении сверхпроводимости металлов в условиях низких температур [1]. Детектором слабых магнитных полей является сверхпроводящий квантовый интерферометр (СКВИД-магнитометр, от англ. SQUID -Superconducting Quantum Interference Device). Его используют в установке для измерения магнитного поля на поверхности головы человека, которая получила название магнитного энцефалографа. СКВИД-магнитометр позволяет измерять магнитное поле с точностью до 10 -15 Тл, тогда как порядок сигналов, регистрируемых на поверхности головы, составляет 10 -12 Тл. Основной задачей анализа данных магнитной энцефалографии (МЭГ) является выделение полезного сигнала на фоне общей спонтанной активности мозга. Известно, что в экспериментах с вызванной активностью мозга искомый сигнал имеет амплитуду на порядок слабее амплитуды фоновой активности и лежит в той же полосе частот [2]. При этом эксперименты с вызванными потенциалами (ВП) имеют в качестве необходимых для усреднения опорных точек запись моментов подачи стимула. При * pnm@impb.ru

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Voices behind the left shoulder: Two patients with right-sided temporal lobe epilepsy

Cited by 11 publications

References 13 publications

A comprehensive review of auditory verbal hallucinations: lifetime prevalence, correlates and mechanisms in healthy and clinical individuals

A comprehensive review of auditory verbal hallucinations: lifetime prevalence, correlates and mechanisms in healthy and clinical individuals

From Tones in Tinnitus to Sensed Social Interaction in Schizophrenia: How Understanding Cortical Organization Can Inform the Study of Hallucinations and Psychosis

The Method to Reveal Pathologic Activity of Human Brain in the Magnetic Encephalography Data

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