Voigt‐Futcher pigmentary demarcation lines

Zieleniewski, Łukasz; Schwartz, Robert A.; Goldberg, David J.; Handler, Marc Z.

doi:10.1111/jocd.12884

Cited by 15 publications

(19 citation statements)

References 26 publications

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“…Medicine's classification of common, harmless, non-White characteristics as aberrant is not unique to BEN. It is seen in diagnoses such as Voigt-Futcher lines, the normal demarcations between areas of differing pigmentation such as between the anterior and posterior arm, 27 or steatopygia, which describes a higher accumulation of adipose tissue in the buttocks than what is typically seen in White people. 28 It is no surprise that systemic racism, structures of discriminatory policies and practices that assign privilege on the basis of skin color, is insidiously embedded in systems that we blithely invoke in our daily practice.…”

Section: Introductionmentioning

confidence: 99%

When non-Whiteness becomes a condition

Merz

Achebe

2021

Blood

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The term "benign ethnic neutropenia" describes the phenotype of having an ANC less than 1500 cells/uL with no increased risk of infection. This is most commonly seen in those of African ancestry. In addition, ANC ranges from countries in Africa emphasize that ANC levels below 1500 cell/uL are common and harmless. The lower ANC levels are driven by the Duffy null [Fy(a-b-)] phenotype which is protective against malaria and seen in 80-100% of those of Sub-Saharan African ancestry and <1% of those of Caucasian descent. Benign ethnic neutropenia is clinically insignificant, but the average ANC values differ from what is typically seen in those of European descent. Thus, the predominantly white American medical system has described this as a condition. This labelling implicitly indicates that common phenotypes in non-white populations are abnormal or wrong. We feel that it is important to examine and rectify practices in hematology that contribute to systemic racism.

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Section: Introductionmentioning

confidence: 99%

When non-Whiteness becomes a condition

Merz

Achebe

2021

Blood

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“…ND should be distinguished from a variety of disorders, including nevus anemicus, hypomelanosis of Ito, Fitzpatrick patches (ash leaf spots) of tuberous sclerosis, vitiligo, indeterminate leprosy, and pigmentary demarcation lines (Table ) …”

Section: Differential Diagnosismentioning

confidence: 99%

“…Pigmentary demarcation lines (PDLs), also known as Futcher's lines, are physiological transitions from skin that is of deeper pigmentation to that of lighter pigmentation (Fig. ).…”

Section: Differential Diagnosismentioning

confidence: 99%

Nevus depigmentosus: review of a mark of distinction

Ullah

Schwartz

2019

Int J Dermatology

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Nevus depigmentosus (ND), also known as nevus achromicus or achromic nevus, is an uncommon congenital hypomelanosis of the skin that is often characterized as being nonprogressive and having serrated borders. It needs to be distinguished from other hypopigmented skin conditions such as nevus anemicus, hypomelanosis of Ito, Fitzpatrick patches (ash leaf spots) of tuberous sclerosis, vitiligo, indeterminate leprosy, and pigment demarcation lines. Treatment may be desired for aesthetic and possible psychosocial considerations. We review and update knowledge about ND and its simulants.

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“…1 Pigmentary demarcation lines (PDL) are defined as physiological, abrupt transition zones from deeper pigmented skin to lighter skin. 2 Types A to E occur on the body, while types F, G and H occur on the face. The axial-neural theory and pigmentary mosaicism have been implicated in the unclear pathogenesis.…”

Section: Introductionmentioning

confidence: 99%

“…Pigmentary demarcation lines (PDL) are defined as physiological, abrupt transition zones from deeper pigmented skin to lighter skin 2 . Types A to E occur on the body, while types F, G and H occur on the face.…”

Section: Introductionmentioning

confidence: 99%

A clinical, dermoscopic, histopathological and immunohistochemical study of melasma and facial pigmentary demarcation lines in the skin of color

Khunger

Kandhari²,

Singh

et al. 2020

Dermatologic Therapy

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Melasma and facial pigmentary demarcation lines (FPDL) are common causes of patterned facial pigmentation that may mimic each other. There is a paucity of studies investigating these two conditions. The objective of this study was to make a detailed comparative analysis of these disorders. A clinical, dermoscopic, histopathological and immunohistochemical analysis of lesional and perilesional skin was conducted in 20 patients each of melasma and FDPL. The most common morphological patterns were centrofacial in melasma and W-shaped pattern in FPDL. Dermoscopy in melasma revealed similar patterns in lesional and perilesional skin, whereas FPDL did not. Histopathology of melasma revealed increased melanin in the suprabasal and basal layers (100%), melanophages in the upper dermis and solar elastosis (65%) in contrast to FPDL, wherein increased basilar melanin (75%) and dermal melanophages were the key findings. Expression of vascular endothelial growth factor and stem cell factor was slightly increased in lesional melasma skin, but not in FPDL. The study was limited by its small sample size and immunohistochemistry carried out in a few patients. Melasma and FPDL, although similar in presentation, are distinct entities. Dermoscopy, histology and immunohistochemistry reveal subtle differences.

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Voigt‐Futcher pigmentary demarcation lines

Cited by 15 publications

References 26 publications

When non-Whiteness becomes a condition

When non-Whiteness becomes a condition

Nevus depigmentosus: review of a mark of distinction

A clinical, dermoscopic, histopathological and immunohistochemical study of melasma and facial pigmentary demarcation lines in the skin of color

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