Volatile oils from leaves and stem barks of Cedrela fissilis (Meliaceae): chemical composition and antibacterial activities

Abstract

The volatile oils from the leaves and stem barks of Cedrela fissilis were submitted to GC-MS analysis and separation by adsorption chromatography. The fractions were analysed by GC, 1 H-and 13 C-NMR as well as GC-MS. The major components found in the leaf oil were β β β β β-caryophyllene (26.3%) and bicyclogermacrene (34.6%), while in the stem bark oil the major compounds were β β β β β-bisabolene (10.9%) and globulol (10.9%). In an antibacterial assay, only the leaf oil was able to inhibit growth of Staphylococcus aureus and Eschorichia coli.

Identification of the main volatile compounds in the leaf and flower of Tithonia diversifolia (Hemsl) Gray

“…In fact the essential oils of Pinus pinea and Bulpleurum frutescescens, whose major constituents are a-pinene and b-caryophyllene, are useful both as antimicrobials and anti-inflammatories [13,14]. The germacrene D-, b-caryophyllene-and bicyclogermacrene-rich essential oils of some Stachys species, Cedrela fissilis and Origanum · dolichosiphon are also effective at inhibiting the growth of some microbes [15][16][17]. In addition, the anti-inflammatory and anti-ulcer activities of the leaf oil of Casearia sylvestris have been attributed to the presence, in large quantities, of the three sesquiterpene hydrocarbon compounds described above [18].…”

In vitro control of food-borne and food spoilage bacteria by essential oil and ethanol extracts of Lonicera japonica Thunb.

“…chloroform and ethyl acetate have potential activity against some representative food-borne pathogens, except for Pseudomonas and E. coli O157. The antibacterial activity L. japonica essential oil could be contributed to the presence of some major components, such as trans-nerolidol, caryophyllene oxide, linalool, p-cymene, hexadecanoic acid, eugenol, geraniol, trans-linalo oloxide, globulol, pentadecanoic acid, veridiflorol, benzyl alcohol and phenylethyl alcohol (El-Sakhawy, El-Tantawy, Ross, & El-Sohly, 1998;Lago et al, 2004;Melliou, Stratis, & Chinou, 2007). On the other hand, the components in lower amounts such as citronellyl acetate, geranylacetone, hexahydrofarnesyl acetone, 1,8-cineole, a-cadinol, tetradecanoic acid, dodecanal, and aromadendrene may also contribute to antimicrobial activity of the oil (Melliou et al, 2007;Vardar-Ünlü, Silici, & Ünlü, 2008).…”

Chemical Compounds and Biologic Activities: A Review of Cedrela Genus

“…Stem bark oil [39] γ-Muurolene (36) C. odorata L. Bark and sapwood essential oil [21] α-Copaene (37)…”