Voltammetric analysis of antihistamine drug cetirizine and paracetamol at poly(L-Leucine) layered carbon nanotube paste electrode

Pushpanjali, Pemmatte A.; Manjunatha, Jamballi G.; Hareesha, N.; Souza, Edwin S. D’; Charithra, M. M.; Prinith, Nambudumada S.

doi:10.1016/j.surfin.2021.101154

Cited by 62 publications

(18 citation statements)

References 34 publications

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“…Electrochemical approaches, on the other hand, have several benefits, such as affordability, simplicity, rapidity, and user friendliness, being preferred to classical analysis methods. Over the past decades, a variety of materials have been employed as electrode modifiers in order to enhance AMP detection: bismuth oxide nanoparticles [ 24 ], molecularly imprinted polymeric micelles [ 25 ], electropolymerized-molecularly imprinted polypyrrole [ 26 ], poly(Patton and Reeder’s reagent) [ 27 ], carbon nanotubes [ 28 ]; poly (L-Leucine)-layered carbon nanotube [ 29 ], multiwalled carbon nanotube and β-cyclodextrin [ 30 ], nafion/TiO 2 -graphene [ 31 ], and graphene oxide-Y 2 O 3 nanocomposite [ 32 ].…”

Section: Introductionmentioning

confidence: 99%

Enhanced Acetaminophen Electrochemical Sensing Based on Nitrogen-Doped Graphene

Măgeruşan

Pogăcean

Pruneanu

2022

IJMS

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Because of the widespread acetaminophen usage and the danger of harmful overdosing effects, developing appropriate procedures for its quantitative and qualitative assay has always been an intriguing and fascinating problem. A quick, inexpensive, and environmentally friendly approach based on direct voltage anodic graphite rod exfoliation in the presence of inorganic salt aqueous solution ((NH4)2SO4–0.3 M) has been established for the preparation of nitrogen-doped graphene (exf-NGr). The XRD analysis shows that the working material appears as a mixture of few (76.43%) and multi-layers (23.57%) of N-doped graphenes. From XPS, the C/O ratio was calculated to be 0.39, indicating a significant number of structural defects and the existence of multiple oxygen-containing groups at the surface of graphene sheets caused by heteroatom doping. Furthermore, the electrochemical performances of glassy carbon electrodes (GCEs) modified with exf-NGr for acetaminophen (AMP) detection and quantification have been assessed. The exf-NGr/GCE-modified electrode shows excellent reproducibility, stability, and anti-interfering characteristics with improved electrocatalytic activity over a wide detection range (0.1–100 µM), with a low limit for AMP detection (LOD = 3.03 nM). In addition, the developed sensor has been successfully applied in real sample analysis for the AMP quantification from different commercially available pharmaceutical formulations.

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Section: Introductionmentioning

confidence: 99%

Enhanced Acetaminophen Electrochemical Sensing Based on Nitrogen-Doped Graphene

Măgeruşan

Pogăcean

Pruneanu

2022

IJMS

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“…Compared to these methods electrochemical methods are respectable and give a suitable platform for quantification, fast response, low finding limits, and outstanding stability. [13][14][15][16][17] Also, which is important for several benefits, such as lesser instrumentation cost, shorter working time, and problem-free working procedures with low LOD, high sensitivity, selectivity, reproducibility, and stability for the examination of different electro and bioactive molecules. [18][19][20][21][22][23][24][25][26][27] RT is an electroactive constituent and most possibly provides redox behaviour at the electrode surface through electrocatalysis and thus the electrochemical methods become a more significant for RT investigation.…”

Section: Introductionmentioning

confidence: 99%

“…These methods need a lengthy process and usually require costly instrumentation, and more pre‐treatment procedures. Compared to these methods electrochemical methods are respectable and give a suitable platform for quantification, fast response, low finding limits, and outstanding stability [13–17] . Also, which is important for several benefits, such as lesser instrumentation cost, shorter working time, and problem‐free working procedures with low LOD, high sensitivity, selectivity, reproducibility, and stability for the examination of different electro and bioactive molecules [18–27] …”

Section: Introductionmentioning

confidence: 99%

Electrochemically Polymerized DL‐Phenylalanine‐Deposited Graphene Paste Electrode for the Detection of Rutin

et al. 2023

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The sensitive, economical, green, and simple voltammetric sensor for the detection of the redox behaviour of rutin (RT) was prepared by the electrochemical polymerization approach. The constructed polymerized DL-phenylalanine (DL-PN) modified graphene paste electrode (MGPE) and bare graphene paste electrode (BGPE) were elucidated using cyclic voltammetry (CV), differential pulse voltammetry (DPV), electrochemical impedance spectroscopic (EIS) and field emission scanning electron microscopic (FE-SEM) approaches. The analysis of RT in phosphate-buffered saline (PBS) of pH 6.5 was demonstrated by the application of a modified electrode (Poly(DL-PN)MGPE) with higher electrocatalytic activity and active sites as compared to BGPE. The important electrochemical parameters such as the influence of PBS, pH, scan rate, and concentration of RT on Poly(DL-PN)MGPE were evaluated. The variation of scan rate and PBS pH assessment discloses that the RT redox nature at Poly(DL-PN)MGPE surface has proceeded via pH-dependant and adsorption-controlled pathways. The Poly(DL-PN)MGPE senses RT in the range from 0.2 to 10.0 μM with a lower limit of detection (LOD) value of 8.31 nM and a limit of quantification (LOQ) of 27.70 nM. The Poly(DL-PN)MGPE shows excellent reproducibility, antifouling nature, repeatability, and stability for the detection of RT. Also, the Poly(DL-PN)MGPE analytical applicability was discussed for RT detection in citrus fruit juice samples.

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“…Various analytical methods may be used for the determination of CTZ, among them: high performance liquid chromatography (HPLC) [ 5 , 6 , 7 ], liquid chromatography (LC) [ 8 , 9 ], spectrophotometry [ 10 , 11 ], capillary electrophoresis [ 12 , 13 ], and voltammetry [ 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 ]. Although the methods mentioned can be applied successfully in the determination of CTZ, some of them may suffer from several disadvantages.…”

Section: Introductionmentioning

confidence: 99%

“…The literature reports that CTZ was determined using voltammetric techniques and different types of solid electrodes: the boron-doped diamond electrode [ 19 ], the graphite pencil electrode [ 20 ], and the modified GCE [ 15 , 17 , 21 , 23 ] and CPE [ 14 , 16 , 18 , 22 , 24 ].…”

Section: Introductionmentioning

confidence: 99%

New Electrochemical Sensor Based on Hierarchical Carbon Nanofibers with NiCo Nanoparticles and Its Application for Cetirizine Hydrochloride Determination

et al. 2022

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A new electrochemical sensor based on hierarchical carbon nanofibers with Ni and Co nanoparticles (eCNF/CNT/NiCo-GCE) was developed. The presented sensor may be characterized by high sensitivity, good electrical conductivity, and electrocatalytic properties. Reproducibility of its preparation expressed as %RSD (relative standard deviation) was equal to 9.7% (n = 5). The repeatability of the signal register on eCNF/CNT/NiCo-GCE was equal to 3.4% (n = 9). The developed sensor was applied in the determination of the antihistamine drug—cetirizine hydrochloride (CTZ). Measurement conditions, such as DPV (differential pulse voltammetry) parameters, supporting electrolyte composition and concentration were optimized. CTZ exhibits a linear response in three concentration ranges: 0.05–6 µM (r = 0.988); 7–32 (r = 0.992); and 42–112 (r = 0.999). Based on the calibration performed, the limit of detection (LOD) and limit of quantification (LOQ) were calculated and were equal to 14 nM and 42 nM, respectively. The applicability of the optimized method for the determination of CTZ was proven by analysis of its concentration in real samples, such as pharmaceutical products and body fluids (urine and plasma). The results were satisfactory and the calculated recoveries (97–115%) suggest that the method may be considered accurate. The obtained results proved that the developed sensor and optimized method may be used in routine laboratory practice.

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Voltammetric analysis of antihistamine drug cetirizine and paracetamol at poly(L-Leucine) layered carbon nanotube paste electrode

Cited by 62 publications

References 34 publications

Enhanced Acetaminophen Electrochemical Sensing Based on Nitrogen-Doped Graphene

Enhanced Acetaminophen Electrochemical Sensing Based on Nitrogen-Doped Graphene

Electrochemically Polymerized DL‐Phenylalanine‐Deposited Graphene Paste Electrode for the Detection of Rutin

New Electrochemical Sensor Based on Hierarchical Carbon Nanofibers with NiCo Nanoparticles and Its Application for Cetirizine Hydrochloride Determination

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