Voltammetric Oxidation of Ambroxol and Application to Its Determination in Pharmaceuticals and in Drug Dissolution Studies

Demircigil, B. Tolga; Uslu, Bengi; Özkan, Yalçın; Şentürk, Zühre

doi:10.1002/elan.200390029

Cited by 27 publications

(5 citation statements)

References 22 publications

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“…Analgesics (acetaminophen, morfine) C Garcia-Fernandez et al 2000, Ni et al 2004, Uliana et al 2010, Ozcan and Sahin 2011GC Garrido et al 2002, Garrido et al 2003a,b, Torriero et al 2006, Kashefi-Kheyrabadi and Mehrgardi 2012BDD Wangfuengkanagul and Chailapakul 2002, Lourenção et al 2009, Sartori et al 2009, Švorc et al 2012aCNT Wan et al 2009a,b, Goyal et al 2010a,b,c,d,e, Sanghavi and Srivastava 2010,b, Shahrokhian and Asadian 2010, Habibi et al 2011, Lu and Tsai 2011, Arvand and Gholizadeh, 2013 Vela et al 2001, El-Enany et al 2002, Ozaltin et al 2002, Ozaltin et al 2002, Morais et al 2003, Nouws et al 2005a,b, 2006a Belal et al 2001a,b, 2002a, 2001b, 2003, Dumitrescu et al 2001, Ghandour et al 2001, El-Ries et al 2002, Tamer et al 2002, Demircigil et al 2003, Ghoneim and Tawfik 2003a,b, Ioannides et al 2003, Prieto et al 2003, Razak et al 2003 Several general aspects dealing with the voltammetric screening of pharmaceuticals can be applied: -Electrode modification strategies generally used to promote an electrocatalytic effect on the oxidation or reduction of the analyte. In most cases, synergistic eff...…”

Section: Family (Representative Analytes) Electrode Referencementioning

confidence: 97%

Voltammetric/amperometric screening of compounds of pharmacological interest

Doménech‐Carbó

Carvalho

Martini

et al. 2014

Reviews in Analytical Chemistry

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Voltammetric and amperometric methods for screening compounds of pharmacological interest are reviewed on the basis of the types of electrodes and analytical strategies. The scope of conventional voltammetric and amperometric methods has been considerably expanded in the last years due to the development of a plethora of modified electrodes, in particular, those involving nanocomposites. The application of solid state voltammetric techniques for pharmacological screening has been also reviewed.

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Section: Family (Representative Analytes) Electrode Referencementioning

confidence: 97%

Voltammetric/amperometric screening of compounds of pharmacological interest

Doménech‐Carbó

Carvalho

Martini

et al. 2014

Reviews in Analytical Chemistry

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“…Proposed mechanisms and a similar type of mechanism are also given for the oxidation of pyrrole ring in literature 11,[20][21][22][23][24] .…”

Section: Proposed Mechanismmentioning

confidence: 97%

Electrochemical oxidation of atorvastatin and its adsorptive stripping determination in pharmaceutical dosage forms and biological fluids

Eskiköy

Durmuș

Kılıç

2011

Collect. Czech. Chem. Commun.

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Electrochemical behavior of atorvastatin (AT) and optimum conditions to its quantitative determination were investigated using voltammetric methods. Some electrochemical parameters such as diffusion coefficient, surface coverage of adsorbed molecules, electron transfer coefficient, standard rate constant and number of electrons were calculated using the results of cyclic voltammetry. A tentative mechanism for the oxidation for AT has been suggested. The oxidation signal of AT molecule was used to develop fully validated, new, rapid, selective and simple square-wave anodic adsorptive stripping voltammetric (AdsSWV) and differential pulse anodic stripping voltammetric (AdsDPV) methods to direct determination of AT in pharmaceutical dosage forms and biological samples. For the AdsDPV and AdsSWV techniques, linear working ranges were found to be 1.0 × 10 -7 -5.0 × 10 -6 and 3.0 × 10 -7 -5.0 × 10 -6 mol l -1 , respectively. The detection limits obtained from AdsDPV and AdsSWV were calculated to be 6.55 × 10 -8 and 1.53 × 10 -7 mol l -1 , respectively. The methods were successfully applied to assay the drug in tablets, human blood serum and human urine.

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“…Com o advento das técnicas eletroanalíticas, os sensores eletroquímicos ganharam novos espaços nas diversas áreas de pesquisas. Dessa forma, vários trabalhos vêm sendo publicados em revistas especializadas, em que os autores relatam diferentes tipos de eletrodos utilizados na quantificação de espécies eletroativas [3][4][5][6][7] . Podese destacar entre eles os eletrodos de pasta de carbono (EPCs) [8][9][10][11][12] .…”

Section: Breve Histórico Sobre Os Eletrodos De Pasta De Carbono Modifunclassified

Eletrodos de pasta de carbono modificados com ácidos húmicos: estudo e determinação de metais em meio aquoso

Crespilho¹,

Rezende²

2004

Quím. Nova

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carbon paste electrodes modified with humic acids have been used for studying the behavior of metals in aqueous solutions. Many parameters influence the performance of the electrodes, such as the humic acid ratio, the nature of the humic acid, the accumulation time, the pH, the scan rate, and the preparation of the electrodes itself. There are various methos of preparing the electrodes. The goal of this paper is to review some of them. The advantages of using electrodes modified with humic acids as electrochemical sensors for evaluating metals in aqueous solution are stressed.Keywords: humic acid; modified electrode; metals. INTRODUÇÃO Breve histórico sobre os eletrodos de pasta de carbono modificadosA Química Analítica vem aperfeiçoando cada vez mais os méto-dos e técnicas que possam determinar quantidades muito pequenas de analitos em soluções aquosas. As técnicas eletroanalíticas, principalmente aquelas em que a varredura de potenciais gera sinais analí-ticos na forma de correntes, têm sido empregadas na determinação de diversos analitos ; EPC modificados com ácidos húmicos para estudo com metais e pesticidas [9][10][11][12] , entre outros. A partir de 1992, alguns pesquisadores descobriram grandes vantagens em se modificar um EPC com ácidos húmicos (AH) [9][10][11][12] . Para entender o porquê de se modificar um EPC com AH, é preciso compreender as características estruturais e a reatividade dessas moléculas. VANTAGENS DA UTILIZAÇÃO DE ÁCIDOS HÚMICOS COMO MODIFICADORES EM EPCsEmbora não haja um modelo definido sobre a estrutura dos AH [29][30][31] , existe um fato que muito interessa àqueles que trabalham com

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Voltammetric Oxidation of Ambroxol and Application to Its Determination in Pharmaceuticals and in Drug Dissolution Studies

Cited by 27 publications

References 22 publications

Voltammetric/amperometric screening of compounds of pharmacological interest

Voltammetric/amperometric screening of compounds of pharmacological interest

Electrochemical oxidation of atorvastatin and its adsorptive stripping determination in pharmaceutical dosage forms and biological fluids

Eletrodos de pasta de carbono modificados com ácidos húmicos: estudo e determinação de metais em meio aquoso

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