Voltammetry in sheep's blood: Membrane-free amperometric measurement of O2 concentration

Experimental Voltammetry Analyzed Using Artificial Intelligence: Thermodynamics and Kinetics of the Dissociation of Acetic Acid in Aqueous Solution

“…Similarly, the voltammetry of blood reveals signals attributed to the electro-reduction of oxygen released from oxy-hemoglobin close to an electrode. 47 − 49 Again, the chemistry is not simple: four oxygen molecules are bound to each hemoglobin and have different kinetics and thermodynamics of release. A chemically over-simplified analysis using AI trained for a simple mechanism would likely give erroneous or misleading output.…”

“…The application of an AI program trained for a simple dissociative CE process could not capture the essential content of the voltammetry/chronoamperometry and requires chemical expertise from the experimenter. Similarly, the voltammetry of blood reveals signals attributed to the electro-reduction of oxygen released from oxy-hemoglobin close to an electrode. − Again, the chemistry is not simple: four oxygen molecules are bound to each hemoglobin and have different kinetics and thermodynamics of release. A chemically over-simplified analysis using AI trained for a simple mechanism would likely give erroneous or misleading output.…”