Volume History Response of Airway Resistance

Ahmad, Hamna; Khan, Muhammad Sikander Ghayas; Memon, Muhammad; Khan, Maria

doi:10.1007/978-1-4615-1933-1_23

Cited by 1 publication

(4 citation statements)

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“…Therefore, the pressure Bronchial Hysteresis 201 resulting from the sum of all the pressures is that exerted by the parenchymal attachments (Figure 9), which is transmitted by the bronchial tissue to the internal bronchial wall. (3) The different tissue components of the bronchial wall [2,6,7]. The results obtained from measuring A i (Figure 7) were similar to those obtained by other authors [5,11,16].…”

Section: Discussionsupporting

confidence: 89%

“…In our opinion, the following are the 3 most important factors involved in bronchial hysteresis: (1) Volume history, which refers to the point during the respiratory cycle at which the process is studied [6]. (2) The pressure of the parenchymal attachments.…”

Section: Discussionmentioning

confidence: 99%

“…The bronchial wall may be of influence in bronchial hysteresis due to its intrinsic elasticity [1] and the active contraction of the smooth muscle [6,7].…”

mentioning

confidence: 99%

“…Bronchial hysteresis depends on several factors, such as the volume history or stage in the respiratory cycle [2,6], the tension of the pulmonary parenchyma [1,5], and the contractile and noncontractile elements of the bronchus. The bronchial wall may be of influence in bronchial hysteresis due to its intrinsic elasticity [1] and the active contraction of the smooth muscle [6,7].…”

mentioning

confidence: 99%

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Bronchial Hysteresis: Morphometric Study on the Rat Lung

Guzman

2003

Experimental Lung Research

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The bronchus is an imperfect elastic structure because part of the energy transmitted in inspiration is not recovered in expiration. This phenomenon is known as bronchial hysteresis. The aim of this paper is to demonstrate bronchial hysteresis using morphometric techniques: differences in the wall and the bronchial lumen, between inspiration and expiration. Sixty disease-free Fischer rats were used, organized into 4 groups. The lungs from the first and second groups were fixed in inflation at 10 and 20 cm of H(2)O transpulmonary pressure (Ptp), respectively. Those taken from the third and fourth groups were fixed in deflation at 20 and 10 cm Ptp, respectively. The lungs were removed from the thorax, filled with air, and fixed via the pulmonary artery. A morphometric study of the following variables was performed: pulmonary volume (P(v)), dead space (DS) internal bronchial area (A(i)), which is the area of the bronchial lumen, and total wall area (WA(t)), which is the area of the bronchial wall. The lungs fixed in deflation gave higher values for all the variables than those fixed in inflation. The P(v), DS, and A(i) increased/decreased with the rise/fall of the Ptp; A(i) was the only variable to display statistically significant values (P<.05) when the Ptp was modified. WA(t) showed statistically significant differences between the lungs fixed in inflation and deflation and underwent no modification when the Ptp was varied. This study supports the hypothesis that bronchial hysteresis can be demonstrated using morphometric techniques because differences were observed in the lumen and wall of the bronchus between inflation and deflation.

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Section: Discussionsupporting

confidence: 89%

Section: Discussionmentioning

confidence: 99%

“…The bronchial wall may be of influence in bronchial hysteresis due to its intrinsic elasticity [1] and the active contraction of the smooth muscle [6,7].…”

mentioning

confidence: 99%