“…Accurate volume measurements usually are possible with 3-D EUS, being useful for treatment planning and monitoring of tumor response. 65,71 However, based on the limited published data, it is not yet clear whether the results obtained by 3-D EUS are significantly better as compared with the results of 2-dimensional EUS. Consequently, 3-D EUS should be validated in blinded, multicenter studies including large numbers of patients, in comparison with other cross-sectional imaging methods (eg, magnetic resonance imaging) and pathology validation.…”